Prof David Finn

B.Sc. (Hons)., Ph.D.

Contact Details

Personal Professor
Dept. of Pharmacology &
Therapeutics
NUI, Galway

T: Ext. 5280
E: david.finn@nuigalway.ie
Professor of Pharmacology and Therapeutics
Pharmacology

T: Ext. 5280
E: david.finn@nuigalway.ie
 
researcher

Biography

Background
Professor David Finn is Professor of Pharmacology and Therapeutics, Science Foundation Ireland Principal Investigator and Co-Founder and Co-Director of the Centre for Pain Research ( http://www.nuigalway.ie/centre-for-pain-research ) at NUI Galway.  Professor Finn graduated with a BSc (Hons) in Biotechnology from NUI Galway in 1997 and a PhD in Neuroscience from the University of Bristol in 2001.  From 2001 to 2004, Professor Finn worked as a Post-doctoral Research Fellow at the Institute of Neuroscience, University of Nottingham.  In 2004, he was appointed to a Lectureship (Below the Bar) in the Department of Physiology, NUI, Galway.  In 2007, he was appointed to a Lectureship (Above the Bar) in Pharmacology and Therapeutics and to a Personal Professorship in Pharmacology and Therapeutics in 2014.  The overall aim of Professor Finn’s research is to increase our understanding of the neurobiology of pain and psychiatric disorders including anxiety and depression.  Professor Finn is a former recipient of the President of Ireland Young Researcher Award from Science Foundation Ireland, the Wyeth Award for outstanding research in Preclinical Psychopharmacology from the British Association for Psychopharmacology and the Pain Research Medal from the Irish Pain Society.  He is currently President of the Irish Pain Society, and he sits on the Scientific Advisory Panel of the European College of Neuropsychopharmacology, as well as the Council of the Biomedical Sciences Section of the Royal Academy of Medicine in Ireland.  He is also a member of the International Cannabinoid Research Society, the Society for Neuroscience and the International Association for the Study of Pain and a member of the Editorial Board of the Journal of Psychopharmacology and Frontiers in Neuropharmacology.  From 2012 - 2013 Prof. Finn served as Director of the Galway Neuroscience Centre (http://ncbes.nuigalway.ie/research/galway-neuroscience-centre/).  In addition to directing his research programme, Professor Finn teaches a range of Pharmacology topics to undergraduate and postgraduate science and medical students.  Summary of Research Interests The overall objective of Professor Finn’s research is to increase understanding of the neurobiological mechanisms underlying the development and treatment of pain, inflammation, mood disorders and impaired cognition.  This work is concerned with elucidating the role of a number of different receptor types (cannabinoid, opioid, adrenoceptor, imidazoline, serotonin, vanilloid, N-type Ca2+channels) in mediating and modulating behavioural, neurochemical and neuroendocrine responses relevant to pain, anxiety, depression and cognition. An integrative, whole systems neuroscience approach is employed, combining behavioural models with in vivo and ex vivo measurement of neurotransmitters, lipids (e.g. endocannabinoids), proteins or genes (e.g. cytokines, receptors, enzymes, signal transduction molecules, immediate early genes and transription factors) in discrete brain regions and assessment of hypothalamo-pituitary-adrenal axis function.  This research, which is funded from a number of competitive sources including Science Foundation Ireland, the Irish Health Research Board, The Wellcome Trust, the Higher Education Authority, the Irish Research Council and Industry (e.g. Covidien, Alkermes) aims to make a significant contribution to the knowledge-base on pain and stress-related psychiatric disorders and support the development of novel therapeutic agents for their treatment.  Research Techniques Behavioural models of pain, inflammation, aversion and cognition; Systemic and central administration of drugs; In vivo microdialysis; HPLC; Liquid chromatography  with tandem mass spectrometry for measurment of endocannabinoids and related lipids; In vitro receptor autoradiography and [35S]GTPyS autoradiography; ELISA; Western blotting; Radioimmunoassay; Radiometric enzyme activity assays;  In situ hybridisation; Immunohistochemistry.  
 

Research Interests

Summary of Research Interests

The overall objective of Professor Finn’s research is to increase understanding of the neurobiological mechanisms underlying the development and treatment of pain, inflammation, mood disorders and impaired cognition.  This work is concerned with elucidating the role of a number of different receptor types (cannabinoid, opioid, adrenoceptor, imidazoline, serotonin, vanilloid, N-type Ca2+channels) in mediating and modulating behavioural, neurochemical and neuroendocrine responses relevant to pain, anxiety, depression and cognition. An integrative, whole systems neuroscience approach is employed, combining behavioural models with in vivo and ex vivo measurement of neurotransmitters, lipids (e.g. endocannabinoids), proteins or genes (e.g. cytokines, receptors, enzymes, signal transduction molecules, immediate early genes and transcription factors) in discrete brain regions and assessment of hypothalamo-pituitary-adrenal axis function.  This research, which is funded from a number of competitive sources including Science Foundation Ireland, the Irish Health Research Board, The Wellcome Trust, the Higher Education Authority, the Irish Research Council and Industry (e.g. Covidien, Alkermes) aims to make a significant contribution to the knowledge-base on pain and stress-related psychiatric disorders and support the development of novel therapeutic agents for their treatment.

Research Techniques

Behavioural models of pain, inflammation, aversion and cognition; Systemic and central administration of drugs; In vivo microdialysis; HPLC; Liquid chromatography  with tandem mass spectrometry for measurement of endocannabinoids and related lipids; In vitro receptor autoradiography and [35S]GTPyS autoradiography; ELISA; Western blotting; Radioimmunoassay; Radiometric enzyme activity assays;  In situ hybridisation; Immunohistochemistry.

Peer Reviewed Journals

  Year Publication
(2015) 'Differential upregulation of the cannabinoid CB2 receptor in neurotoxic and inflammation-driven rat models of Parkinson's disease'
Concannon, RM,Okine, BN,Finn, DP,Dowd, E (2015) 'Differential upregulation of the cannabinoid CB2 receptor in neurotoxic and inflammation-driven rat models of Parkinson's disease'. Experimental Neurology, 269 :133-141 [DOI] [Details]
(2015) 'Synthesis of polymer-silica hybrid microparticles with defined geometry using surface initiated atom transfer radical polymerization'
Lang, Y,del Monte, F,Finn, DP,Wang, W,Pandit, A (2015) 'Synthesis of polymer-silica hybrid microparticles with defined geometry using surface initiated atom transfer radical polymerization'. Polymer Chemistry, 6 :3014-3017 [DOI] [Details]
(2015) 'CB1 and CB2 Cannabinoid Receptor Antagonists Prevent Minocycline-Induced Neuroprotection Following Traumatic Brain Injury in Mice'
Lopez-Rodriguez, AB,Siopi, E,Finn, DP,Marchand-Leroux, C,Garcia-Segura, LM,Jafarian-Tehrani, M,Viveros, MP (2015) 'CB1 and CB2 Cannabinoid Receptor Antagonists Prevent Minocycline-Induced Neuroprotection Following Traumatic Brain Injury in Mice'. Cerebral Cortex, 25 :35-45 [DOI] [Details]
(2015) 'Chronic administration of amitriptyline differentially alters neuropathic pain-related behaviour in the presence and absence of a depressive-like phenotype'
Burke, NN,Finn, DP,Roche, M (2015) 'Chronic administration of amitriptyline differentially alters neuropathic pain-related behaviour in the presence and absence of a depressive-like phenotype'. Behavioural Brain Research, 278 :193-201 [DOI] [Details]
(2015) 'Development and Characterization of a Novel, Anatomically Relevant Rat Model of Acute Postoperative Pain'
Bree, D,Moriarty, O,Mahony, CM,Morris, B,Bannerton, K,Broom, DC,Kelly, JP,Roche, M,Finn, DP (2015) 'Development and Characterization of a Novel, Anatomically Relevant Rat Model of Acute Postoperative Pain'. Journal Of Pain, 16 :421-435 [DOI] [Details]
(2015) 'Synthesis of Polymer-silica Hybrid Microparticles with Defined Geometry Using Surface Initiated Atom Transfer Radical Polymerization'
Lang, Y., del Monte, F., Finn, D.P., Wang, W., Pandit, A. (2015) 'Synthesis of Polymer-silica Hybrid Microparticles with Defined Geometry Using Surface Initiated Atom Transfer Radical Polymerization'. Polymer Chemistry, 6 :3014-3017 [DOI] [Details]
(2014) 'Microinjection of 2-arachidonoyl glycerol into the rat ventral hippocampus differentially modulates contextually induced fear, depending on a persistent pain state'
Rea, K,Ford, GK,Olango, WM,Harhen, B,Roche, M,Finn, DP (2014) 'Microinjection of 2-arachidonoyl glycerol into the rat ventral hippocampus differentially modulates contextually induced fear, depending on a persistent pain state'. European Journal Of Neuroscience, 39 :435-443 [DOI] [Details]
(2014) 'A role for PPARa in the medial prefrontal cortex in formalin- evoked nociceptive responding in rats'
Okine, BN,Rea, K,Olango, WM,Price, J,Herdman, S,Madasu, MK,Roche, M,Finn, DP (2014) 'A role for PPARa in the medial prefrontal cortex in formalin- evoked nociceptive responding in rats'. British Journal Of Pharmacology, 171 :1462-1471 [DOI] [Details]
(2014) 'Microinjection of 2-arachidonoyl glycerol into the rat ventral hippocampus differentially modulates contextually induced fear, depending on a persistent pain state'
Rea K, Ford GK, Olango WM, Harhen B, Roche M, Finn DP (2014) 'Microinjection of 2-arachidonoyl glycerol into the rat ventral hippocampus differentially modulates contextually induced fear, depending on a persistent pain state'. European Journal Of Neuroscience, 39 (3):435-443 [Details]
(2014) 'A role for PPAR-α in the medial prefrontal cortex in formalin-evoked nociceptive responding in rats'
Okine BN, Rea K, Olango WM, Price J, Roche M, Finn DP (2014) 'A role for PPAR-α in the medial prefrontal cortex in formalin-evoked nociceptive responding in rats'. British J Pharmacology, [Details]
(2014) 'Nano-Structured Polymer-Silica Composite Derived from a Marine Diatom via Deactivation Enhanced Atom Transfer Radical Polymerization Grafting'
O'Connor, J,Lang, Y,Chao, JH,Cao, HL,Collins, L,Rodriguez, BJ,Dockery, P,Finn, DP,Wang, WX,Pandit, A (2014) 'Nano-Structured Polymer-Silica Composite Derived from a Marine Diatom via Deactivation Enhanced Atom Transfer Radical Polymerization Grafting'. Small, 10 :469-473 [DOI] [Details]
(2014) 'Nano-structured polymer-silica composite derived from a marine diatom via deactivation enhanced atom transfer radical polymerization grafting'
O'Connor J, Lang Y, Chao J, Cao H, Collins L, Rodriguez BJ, Dockery P, Finn DP, Wang W, Pandit A (2014) 'Nano-structured polymer-silica composite derived from a marine diatom via deactivation enhanced atom transfer radical polymerization grafting'. Small, 10 (3):469-473 [DOI] [Details]
(2014) 'Fabrication of nanopatterned polymeric microparticles using a diatom as a sacrificial template'
Lang, Y,Finn, DP,Caruso, F,Pandit, A (2014) 'Fabrication of nanopatterned polymeric microparticles using a diatom as a sacrificial template'. Rsc Advances, 4 :44418-44422 [DOI] [Details]
(2014) 'FAAH-mediated modulation of TLR3-induced neuroinflammation in the rat hippocampus'
Henry, RJ,Kerr, DM,Finn, DP,Roche, M (2014) 'FAAH-mediated modulation of TLR3-induced neuroinflammation in the rat hippocampus'. Journal Of Neuroimmunology, 276 :126-134 [DOI] [Details]
(2014) 'Minocycline modulates neuropathic pain behaviour and cortical M1-M2 microglial gene expression in a rat model of depression'
Burke, NN,Kerr, DM,Moriarty, O,Finn, DP,Roche, M (2014) 'Minocycline modulates neuropathic pain behaviour and cortical M1-M2 microglial gene expression in a rat model of depression'. Brain Behavior And Immunity, 42 :147-156 [DOI] [Details]
(2014) 'FAAH-mediated modulation of TLR3-induced neuroinflammation in the rat hippocampus'
Henry RJ, Kerr DM, Finn DP, Roche M (2014) 'FAAH-mediated modulation of TLR3-induced neuroinflammation in the rat hippocampus'. Journal Of Neuroimmunology, [DOI] [Details]
(2014) 'Stress-induced hyperalgesia'
Jennings EM, Okine BN, Roche M, Finn DP (2014) 'Stress-induced hyperalgesia'. Progress in neurobiology, 121C :1-18 [DOI] [Details]
(2014) 'Minocycline modulates neuropathic pain behaviour and cortical M1-M2 microglial gene expression in a rat model of depression'
Burke NN, Kerr DM, Moriarty O, Finn DP, Roche M (2014) 'Minocycline modulates neuropathic pain behaviour and cortical M1-M2 microglial gene expression in a rat model of depression'. Brain Behavior And Immunity, [DOI] [Details]
(2014) 'Chronic administration of amitriptyline differentially alters neuropathic pain-related behaviour in the presence and absence of a depressive-like phenotype'
Burke NN, Finn DP, Roche M (2014) 'Chronic administration of amitriptyline differentially alters neuropathic pain-related behaviour in the presence and absence of a depressive-like phenotype'. Behavioural Brain Research, [DOI] [Details]
(2014) 'Novel molecular correlates of endocannabinoid-mediated fear-conditioned analgesia in rats'
Olango, WM,Geranton, SM,Roche, M,Hunt, SP,Finn, DP (2014) 'Novel molecular correlates of endocannabinoid-mediated fear-conditioned analgesia in rats'. European Journal Of Pain, 18 :182-191 [DOI] [Details]
(2014) 'Impaired endocannabinoid signalling in the rostral ventromedial medulla underpins genotype-dependent hyper-responsivity to noxious stimuli'
Rea, K,Olango, WM,Okine, BN,Madasu, MK,McGuire, IC,Coyle, K,Harhen, B,Roche, M,Finn, DP (2014) 'Impaired endocannabinoid signalling in the rostral ventromedial medulla underpins genotype-dependent hyper-responsivity to noxious stimuli'. Pain, 155 :69-79 [DOI] [Details]
(2013) 'The Cost of Chronic Pain: An Analysis of a Regional Pain Management Service in Ireland'
Gannon, B,Finn, DP,O'Gorman, D,Ruane, N,McGuire, BE (2013) 'The Cost of Chronic Pain: An Analysis of a Regional Pain Management Service in Ireland'. Pain Medicine, 14 :1518-1528 [DOI] [Details]
(2013) 'Integration of TiO2 into the diatom Thalassiosira weissflogii during frustule synthesis'
Lang, Y,del Monte, F,Rodriguez, BJ,Dockery, P,Finn, DP,Pandit, A (2013) 'Integration of TiO2 into the diatom Thalassiosira weissflogii during frustule synthesis'. Scientific Reports, 3 [DOI] [Details]
(2013) 'Maternal deprivation is associated with sex dependant alterations in nociceptive behavioura nd neuriinflammatory mediators in the rat following peripheral nerve injury'
Burke NN, Llorente R, Marco EM, Tong K, Finn DP, Viveros M-P, Roche M (2013) 'Maternal deprivation is associated with sex dependant alterations in nociceptive behavioura nd neuriinflammatory mediators in the rat following peripheral nerve injury'. Journal Of Pain, 14 (10):1173-1184 [DOI] [Details]
(2013) 'Novel molecular correlates of endocannabinoid-mediated fear-conditioned analgesia in rats'
Olango WM, Géranton SM, Roche M, Hunt SP, Finn DP (2013) 'Novel molecular correlates of endocannabinoid-mediated fear-conditioned analgesia in rats'. European Journal Of Pain, 0 (0):0-0 [DOI] [Details]
(2013) 'Altered Neuropathic pain behaviour in a rat model of depression is associated with changes in inflammatory gene expression in the amygdala'
Burke NN, Geoghegan E, Kerr DM, Moriarty O, Finn DP, Roche M. (2013) 'Altered Neuropathic pain behaviour in a rat model of depression is associated with changes in inflammatory gene expression in the amygdala'. Genes Brain And Behavior, 0 (0):0-0 [DOI] [Details]
(2013) 'Impaired endocannabinoid signaling in the rosteromedial medulla underpins genotype-dependant hyper-responsivity to noxious stimuli'
Rea K, Olango WM, Okine BN, Madasu MK, McGuire IC Coyle K, Harhen B, Roche M, Finn DP (2013) 'Impaired endocannabinoid signaling in the rosteromedial medulla underpins genotype-dependant hyper-responsivity to noxious stimuli'. Pain, 154 (4):576-585 [DOI] [Details]
(2013) 'An apPEAling new therapeutic for ulcerative colitis?'
McKernan, D.P. & Finn D.P. (2013) 'An apPEAling new therapeutic for ulcerative colitis?'. Gut, [DOI] [Details]
(2013) 'Altered neuropathic pain behaviour in a rat model of depression is associated with changes in inflammatory gene expression in the amygdala'
Burke, NN,Geoghegan, E,Kerr, DM,Moriarty, O,Finn, DP,Roche, M (2013) 'Altered neuropathic pain behaviour in a rat model of depression is associated with changes in inflammatory gene expression in the amygdala'. Genes Brain And Behavior, 12 :705-713 [DOI] [Details]
(2013) 'Maternal Deprivation Is Associated With Sex-Dependent Alterations in Nociceptive Behavior and Neuroinflammatory Mediators in the Rat Following Peripheral Nerve Injury'
Burke, NN,Llorente, R,Marco, EM,Tong, K,Finn, DP,Viveros, MP,Roche, M (2013) 'Maternal Deprivation Is Associated With Sex-Dependent Alterations in Nociceptive Behavior and Neuroinflammatory Mediators in the Rat Following Peripheral Nerve Injury'. Journal Of Pain, 14 :1173-1184 [DOI] [Details]
(2013) 'Integration of TiO2 into the diatom Thalassiosira weissflogii during frustule synthesis'
Lang Y, del Monte F, Rodriguez BJ, Dockery P, Finn DP, Pandit A (2013) 'Integration of TiO2 into the diatom Thalassiosira weissflogii during frustule synthesis'. Scientific reports, 3 [DOI] [Details]
(2013) 'Functionalization of the living diatom Thalassiosira weissflogii with thiol moieties'
Lang Y, del Monte F, Collins L, Rodriguez BJ, Thompson K, Dockery P, Finn DP, Pandit A (2013) 'Functionalization of the living diatom Thalassiosira weissflogii with thiol moieties'. Commun, 4 [DOI] [Details]
(2013) 'Alterations in the endocannabinoid system in the rat valproic acid model of autism'
Kerr, DM,Downey, L,Conboy, M,Finn, DP,Roche, M (2013) 'Alterations in the endocannabinoid system in the rat valproic acid model of autism'. Behavioural Brain Research, 249 :124-132 [DOI] [Details]
(2013) 'The monoacylglycerol lipase inhibitor JZL184 attenuates LPS-induced increases in cytokine expression in the rat frontal cortex and plasma: differential mechanisms of action'
Kerr, DM,Harhen, B,Okine, BN,Egan, LJ,Finn, DP,Roche, M (2013) 'The monoacylglycerol lipase inhibitor JZL184 attenuates LPS-induced increases in cytokine expression in the rat frontal cortex and plasma: differential mechanisms of action'. British Journal Of Pharmacology, 169 :808-819 [DOI] [Details]
(2013) 'Behavioural, neurochemical and neuroendocrine effects of the endogenous beta-carboline harmane in fear-conditioned rats'
Smith, KL,Ford, GK,Jessop, DS,Finn, DP (2013) 'Behavioural, neurochemical and neuroendocrine effects of the endogenous beta-carboline harmane in fear-conditioned rats'. Journal Of Psychopharmacology, 27 :162-170 [DOI] [Details]
(2013) 'Evidence for a role of GABAergic and glutamatergic signalling in the basolateral amygdala in endocannabinoid-mediated fear-conditioned analgesia in rats'
Rea, K,Olango, WM,Harhen, B,Kerr, DM,Galligan, R,Fitzgerald, S,Moore, M,Roche, M,Finn, DP (2013) 'Evidence for a role of GABAergic and glutamatergic signalling in the basolateral amygdala in endocannabinoid-mediated fear-conditioned analgesia in rats'. Pain, 154 :576-585 [DOI] [Details]
(2013) 'Pharmacological inhibition of monoacylglycerol lipase attenuates LPS-induced increases in cytokine expression in the rat frontal cortex and plasma: differential mechanisms of action'
Kerr DM, Harhen B, Egan LJ, Finn DP, Roche M (2013) 'Pharmacological inhibition of monoacylglycerol lipase attenuates LPS-induced increases in cytokine expression in the rat frontal cortex and plasma: differential mechanisms of action'. British Journal Of Pharmacology, 169 (4):808-819 [DOI] [ARAN Link] [Details]
(2013) 'Functionalization of the living diatom Thalassiosira weissflogii with thiol moieties'
Lang, Y,del Monte, F,Collins, L,Rodriguez, BJ,Thompson, K,Dockery, P,Finn, DP,Pandit, A (2013) 'Functionalization of the living diatom Thalassiosira weissflogii with thiol moieties'. Nature Communications, 4 [DOI] [Details]
(2013) 'Alterations in the endocannabinoid system in the rat valproic acid model of autism'
Kerr DM, Downey L, Conboy M, Finn DP, Roche M (2013) 'Alterations in the endocannabinoid system in the rat valproic acid model of autism'. Behavioural Brain Research, 249 (0):124-132 [DOI] [Details]
(2012) 'The endocannabinoid system and emotional processing: pathophysiology and therapeutic potential'
Finn DP, Viveros MP, Marco EM (2012) 'The endocannabinoid system and emotional processing: pathophysiology and therapeutic potential'. Journal Of Psychopharmacology, 26 (1):3-6 [DOI] [ARAN Link] [Details]
(2012) 'Fear-induced suppression of nociceptive behaviour and activation of signal transduction molecules in the rat periaqueductal grey: role of fatty acid amide hydrolase'
Butler RK, Ford GK, Hogan M, Roche M, Doyle KM, Kelly JP, Kendall DA, Chapman V, Finn DP. (2012) 'Fear-induced suppression of nociceptive behaviour and activation of signal transduction molecules in the rat periaqueductal grey: role of fatty acid amide hydrolase'. Journal Of Psychopharmacology, [ARAN Link] [Details]
(2012) 'The endocannabinoid system and emotional processing: pathophysiology and therapeutic potential'
Finn, DP,Viveros, MP,Marco, EM (2012) 'The endocannabinoid system and emotional processing: pathophysiology and therapeutic potential'. Journal Of Psychopharmacology, 26 :3-6 [DOI] [Details]
(2012) 'Fear-induced suppression of nociceptive behaviour and activation of Akt signalling in the rat periaqueductal grey: role of fatty acid amide hydrolase'
Butler, RK,Ford, GK,Hogan, M,Roche, M,Doyle, KM,Kelly, JP,Kendall, DA,Chapman, V,Finn, DP (2012) 'Fear-induced suppression of nociceptive behaviour and activation of Akt signalling in the rat periaqueductal grey: role of fatty acid amide hydrolase'. Journal Of Psychopharmacology, 26 :83-91 [DOI] [Details]
(2012) 'Pharmacological inhibition of endocannabinoid degradation modulates the expression of inflammatory mediators in the rat hypothalamus following an immunological stressor'
Kerr DM, Burke NN, Ford GK, Connor TJ, Harhen B, Egan LP, Finn DP, Roche M (2012) 'Pharmacological inhibition of endocannabinoid degradation modulates the expression of inflammatory mediators in the rat hypothalamus following an immunological stressor'. Neuroscience, 204 :53-63 [ARAN Link] [Details]
(2012) 'The endocannabinoid system in the rat dorsolateral periaqueductal grey mediates fear-conditioned analgesia and controls fear expression in the presence of nociceptive tone'
Olango, WM,Roche, M,Ford, GK,Harhen, B,Finn, DP (2012) 'The endocannabinoid system in the rat dorsolateral periaqueductal grey mediates fear-conditioned analgesia and controls fear expression in the presence of nociceptive tone'. British Journal Of Pharmacology, 165 :2549-2560 [DOI] [Details]
(2012) 'Validation of an air-puff passive-avoidance paradigm for assessment of aversive learning and memory in rat models of chronic pain'
Moriarty, O,Roche, M,McGuire, BE,Finn, DP (2012) 'Validation of an air-puff passive-avoidance paradigm for assessment of aversive learning and memory in rat models of chronic pain'. Journal Of Neuroscience Methods, 204 :1-8 [DOI] [ARAN Link] [Details]
(2012) 'Pharmacological Activity of Ibuprofen Released from Mesoporous Silica'
Lang, Y,Finn, DP,Pandit, A,Walsh, PJ (2012) 'Pharmacological Activity of Ibuprofen Released from Mesoporous Silica'. Journal Of Materials Science-Materials In Medicine, 23 :73-80 [DOI] [Details]
(2012) 'The fatty acid amide hydrolase inhibitor URB597 exerts anti-inflammatory effects in hippocampus of aged rats and restores an age-related deficit in long-term potentiation'
Murphy N, Cowley TR, Blau CW, Dempsey CN, Noonan J, Gowran A, Tanveer R, Olango WM, Finn DP, Campbell VA, Lynch MA (2012) 'The fatty acid amide hydrolase inhibitor URB597 exerts anti-inflammatory effects in hippocampus of aged rats and restores an age-related deficit in long-term potentiation'. Journal of Neuroinflammation, 9 (1) [Details]
(2012) 'Behavioural, neurochemical and neuroendocrine effects of the endogenous β-carboline harmane in fear-conditioned rats'
Smith KL, Ford GK, Jessop DS, Finn DP (2012) 'Behavioural, neurochemical and neuroendocrine effects of the endogenous β-carboline harmane in fear-conditioned rats'. Journal Of Psychopharmacology, [ARAN Link] [Details]
(2011) 'A role for the ventral hippocampal endocannabinoid system in fear-conditioned analgesia and fear responding in the presence of nociceptive tone in rats'
Ford, GK,Kieran, S,Dolan, K,Harhen, B,Finn, DP (2011) 'A role for the ventral hippocampal endocannabinoid system in fear-conditioned analgesia and fear responding in the presence of nociceptive tone in rats'. Pain, 152 :2495-2504 [DOI] [Details]
(2011) 'Modulation of Conditioned Fear, Fear-Conditioned Analgesia, and Brain Regional C-Fos Expression Following Administration of Muscimol into the Rat Basolateral Amygdala'
Rea, K,Roche, M,Finn, DP (2011) 'Modulation of Conditioned Fear, Fear-Conditioned Analgesia, and Brain Regional C-Fos Expression Following Administration of Muscimol into the Rat Basolateral Amygdala'. Journal Of Pain, 12 :712-721 [DOI] [ARAN Link] [Details]
(2011) 'The effect of pain on cognitive function: a review of clinical and preclinical research'
Moriarty O, McGuire BE, Finn DP (2011) 'The effect of pain on cognitive function: a review of clinical and preclinical research'. Progress in Neurobiology, 93 (3):385-404 [ARAN Link] [Details]
(2011) 'TIME-COURSE OF NIGROSTRIATAL NEURODEGENERATION AND NEUROINFLAMMATION IN THE 6-HYDROXYDOPAMINE-INDUCED AXONAL AND TERMINAL LESION MODELS OF PARKINSON'S DISEASE IN THE RAT'
Walsh, S,Finn, DP,Dowd, E (2011) 'TIME-COURSE OF NIGROSTRIATAL NEURODEGENERATION AND NEUROINFLAMMATION IN THE 6-HYDROXYDOPAMINE-INDUCED AXONAL AND TERMINAL LESION MODELS OF PARKINSON'S DISEASE IN THE RAT'. Neuroscience, 175 :251-261 [DOI] [Details]
(2011) 'Molecular and electrophysiological changes in the prefrontal cortex-amygdala-dorsal periaqueductal grey pathway during persistent pain state and fear-conditioned analgesia'
Butler, RK,Nilsson-Todd, L,Cleren, C,Lena, I,Garcia, R,Finn, DP (2011) 'Molecular and electrophysiological changes in the prefrontal cortex-amygdala-dorsal periaqueductal grey pathway during persistent pain state and fear-conditioned analgesia'. Physiology & Behavior, 104 :1075-1081 [DOI] [Details]
(2011) 'A Dileucine in the Protease of Botulinum Toxin A Underlies Its Long-lived Neuroparalysis TRANSFER OF LONGEVITY TO A NOVEL POTENTIAL THERAPEUTIC'
Wang, JF,Zurawski, TH,Meng, JH,Lawrence, G,Olango, WM,Finn, DP,Wheeler, L,Dolly, JO (2011) 'A Dileucine in the Protease of Botulinum Toxin A Underlies Its Long-lived Neuroparalysis TRANSFER OF LONGEVITY TO A NOVEL POTENTIAL THERAPEUTIC'. Journal Of Biological Chemistry, 286 :6375-6385 [DOI] [Details]
(2010) 'Inhibition by anandamide of 6-hydroxydopamine-induced cell death in PC12 cells'
Mnich, K., Finn, D., Dowd, E., & Gorman, A. (2010) 'Inhibition by anandamide of 6-hydroxydopamine-induced cell death in PC12 cells'. International Journal Of Cell Biology, 818497 [ARAN Link] [Details]
(2010) 'Loss of cannabinoid CB1 receptor expression in the 6-hydroxydopamine-induced nigrostriatal terminal lesion model of Parkinson's disease in the rat'
Walsh, S,Mnich, K,Mackie, K,Gorman, AM,Finn, DP,Dowd, E (2010) 'Loss of cannabinoid CB1 receptor expression in the 6-hydroxydopamine-induced nigrostriatal terminal lesion model of Parkinson's disease in the rat'. Brain Research Bulletin, 81 :543-548 [DOI] [Details]
(2010) 'Endocannabinoid-mediated modulation of stress responses: Physiological and pathophysiological significance'
Finn, DP (2010) 'Endocannabinoid-mediated modulation of stress responses: Physiological and pathophysiological significance'. Immunobiology, 215 :629-646 [DOI] [Details]
(2010) 'The effects of cannabinoid drugs on abnormal involuntary movements in dyskinetic and non-dyskinetic 6-hydroxydopamine lesioned rats'
Walsh, S,Gorman, AM,Finn, DP,Dowd, E (2010) 'The effects of cannabinoid drugs on abnormal involuntary movements in dyskinetic and non-dyskinetic 6-hydroxydopamine lesioned rats'. Brain Research, 1363 :40-48 [DOI] [Details]
(2010) 'Brain CB2 receptors: Implication for Neuropsychiatric disorders'
Roche M, Finn DP (2010) 'Brain CB2 receptors: Implication for Neuropsychiatric disorders'. Pharmaceuticals (Invited Review), 3 (0):2517-2553 [DOI] [ARAN Link] [Details]
(2010) 'Effects of intra-basolateral amygdala administration of rimonabant on nociceptive behaviour and neuronal activity in the presence or absence of contextual fear'
Roche, M,Johnston, P,Mhuircheartaigh, ON,Olango, WM,Mackie, K,Finn, DP (2010) 'Effects of intra-basolateral amygdala administration of rimonabant on nociceptive behaviour and neuronal activity in the presence or absence of contextual fear'. European Journal Of Pain, 14 :487-495 [DOI] [Details]
(2010) 'Enhanced nociceptive responding in two rat models of depression is associated with alterations in monoamine levels in discrete brain regions'
Burke, NN,Hayes, E,Calpin, P,Kerr, DM,Moriarty, O,Finn, DP,Roche, M (2010) 'Enhanced nociceptive responding in two rat models of depression is associated with alterations in monoamine levels in discrete brain regions'. Neuroscience, 171 (0):1300-1313 [DOI] [ARAN Link] [Details]
(2010) 'European College of Neuropsychopharmacology (ECNP)-23rd Congress 28 August-1 September 2010, Amsterdam, the Netherlands'
Finn, DP (2010) 'European College of Neuropsychopharmacology (ECNP)-23rd Congress 28 August-1 September 2010, Amsterdam, the Netherlands'. Idrugs, 13 :753-755 [Details]
(2009) '6-iodonordihydrocapsaicin'
Roche M, Finn DP (2009) '6-iodonordihydrocapsaicin'. Xpharm, 0 (0):0-0 [DOI] [ARAN Link] [Details]
(2009) 'Alterations in Extracellular Levels of Gamma-Aminobutyric Acid in the Rat Basolateral Amygdala and Periaqueductal Gray During Conditioned Fear, Persistent Pain and Fear-Conditioned Analgesia'
Rea, K,Lang, Y,Finn, DP (2009) 'Alterations in Extracellular Levels of Gamma-Aminobutyric Acid in the Rat Basolateral Amygdala and Periaqueductal Gray During Conditioned Fear, Persistent Pain and Fear-Conditioned Analgesia'. Journal Of Pain, 10 :1088-1098 [DOI] [Details]
(2009) 'The effects of synthetic and endogenous imidazoline binding site ligands on neuronal activity in discrete brain regions of naive and restraint-stressed rats'
Smith, KL,Roche, M,Jessop, DS,Finn, DP (2009) 'The effects of synthetic and endogenous imidazoline binding site ligands on neuronal activity in discrete brain regions of naive and restraint-stressed rats'. European Neuropsychopharmacology, 19 :371-380 [DOI] [Details]
(2009) 'Modulation of stress by imidazoline binding sites: implications for psychiatric disorders'
Smith KL, Jessop DS, Finn DP (2009) 'Modulation of stress by imidazoline binding sites: implications for psychiatric disorders'. Stress, 12 (2):97-114 [Details]
(2009) 'Stress-induced analgesia'
Butler RK and Finn DP (2009) 'Stress-induced analgesia'. Progress In Neurobiology, 88 :184-202 [ARAN Link] [Details]
(2009) 'The Role of Supraspinal GABA and Glutamate in the Mediation and Modulation of Pain. In: Acute Pain: Causes, Effects and Treatment'
Rea K and Finn DP (2009) 'The Role of Supraspinal GABA and Glutamate in the Mediation and Modulation of Pain. In: Acute Pain: Causes, Effects and Treatment'. 2009 Nova Science Publishers, Inc, [Details]
(2009) '6-Iodonordihydrocapsaicin'
Roche M and Finn DP (2009) '6-Iodonordihydrocapsaicin'. Xpharm, [Details]
(2009) 'SNC162'
Rea K and Finn DP (2009) 'SNC162'. Xpharm, [Details]
(2009) 'PPAHV (Phorbol 12-phenylacetate 12-acetate 20-homovanillate)'
Ford GK and Finn DP (2009) 'PPAHV (Phorbol 12-phenylacetate 12-acetate 20-homovanillate)'. Xpharm, [Details]
(2009) 'Comments on stress-induced analgesia. Response to the Letter to the Editor by Daniel Le Bars and Pascal Carrive on clinical correlates of stress-induced analgesia: Evidence from pharmacological studies'
Ford, G. K.,Finn, D. P. (2009) 'Comments on stress-induced analgesia. Response to the Letter to the Editor by Daniel Le Bars and Pascal Carrive on clinical correlates of stress-induced analgesia: Evidence from pharmacological studies'. Pain, 142 (1-21-2):167-168 [Details]
(2008) 'Investigating the effects of distracting stimuli on nociceptive behaviour and associated alterations in brain monoamines in rats'
Ford, GK,Moriarty, O,McGuire, BE,Finn, DP (2008) 'Investigating the effects of distracting stimuli on nociceptive behaviour and associated alterations in brain monoamines in rats'. European Journal Of Pain, 12 :970-979 [DOI] [Details]
(2008) 'Augmentation of endogenous cannabinoid tone modulates lipopolysaccharide-induced alterations in circulating cytokine levels in rats'
Roche M, Kelly JP, O'Driscoll M, Finn DP (2008) 'Augmentation of endogenous cannabinoid tone modulates lipopolysaccharide-induced alterations in circulating cytokine levels in rats'. Immunology, 125 (2):263-271 [DOI] [Details]
(2008) 'Imidazoline2 (I2) binding site ligands increase Fos-like immunoreactivity in the naive and restraint-stressed rat brain'
Smith KL, Roche M, Jessop DS, Finn DP (2008) 'Imidazoline2 (I2) binding site ligands increase Fos-like immunoreactivity in the naive and restraint-stressed rat brain'. European Neuropsychopharmacology, 18 (4) [Details]
(2008) 'Identification of discrete sites of action of chronic treatment with desipramine in a model of neuropathic pain'
Jones, K. L., Finn, D. P., Governo, R. J. M., Prior, M. J., Morris, P. G., Kendall, D. A., Marsden, C. A. & Chapman, V. (2008) 'Identification of discrete sites of action of chronic treatment with desipramine in a model of neuropathic pain'. Neuropharmacology, [Details]
(2008) 'Effects of chronic treatment with citalopram on cannabinoid and opioid receptor-mediated G-protein coupling in discrete rat brain regions'
Hesketh, SA,Brennan, AK,Jessop, DS,Finn, DP (2008) 'Effects of chronic treatment with citalopram on cannabinoid and opioid receptor-mediated G-protein coupling in discrete rat brain regions'. Psychopharmacology, 198 :29-36 [DOI] [Details]
(2008) 'Augmentation of endogenous cannabinoid tone modulates lipopolysaccharide-induced alterations in circulating cytokine levels in rats'
Roche, M,Kelly, JP,O'Driscoll, M,Finn, DP (2008) 'Augmentation of endogenous cannabinoid tone modulates lipopolysaccharide-induced alterations in circulating cytokine levels in rats'. Immunology, 125 :263-271 [DOI] [Details]
(2008) 'Endocannabinoid-mediated enhancement of fear-conditioned analgesia in rats: Opioid receptor dependency and molecular correlates'
Butler, RK,Rea, K,Lang, Y,Gavin, AM,Finn, DP (2008) 'Endocannabinoid-mediated enhancement of fear-conditioned analgesia in rats: Opioid receptor dependency and molecular correlates'. Pain, 140 :491-500 [DOI] [Details]
(2008) 'Clinical correlates of Stress-induced Analgesia: Evidence from Pharmacological Studies'
Ford GK and Finn DP (2008) 'Clinical correlates of Stress-induced Analgesia: Evidence from Pharmacological Studies'. Pain, 140 (1):3-7 [Details]
(2007) 'Supraspinal modulation of pain by cannabinoids: the role of GABA and glutamate'
Rea K, Roche M, Finn DP (2007) 'Supraspinal modulation of pain by cannabinoids: the role of GABA and glutamate'. British Journal Of Pharmacology, 152 (5):633-648 [Details]
(2007) 'The effects of pharmacological blockade of the 5-HT6 receptor on formalin-evoked nociceptive behaviour, locomotor activity and hypothalamo-pituitary-adrenal axis activity in rats'
Finn, DP,Forte, KCF,Beckett, SRG,Baxter, JA,Ansell, L,Marsden, CA,Chapman, V (2007) 'The effects of pharmacological blockade of the 5-HT6 receptor on formalin-evoked nociceptive behaviour, locomotor activity and hypothalamo-pituitary-adrenal axis activity in rats'. European Journal Of Pharmacology, 569 :59-63 [DOI] [Details]
(2007) 'The effect of CB1 receptor antagonism in the right basolateral amygdala on conditioned fear and associated analgesia in rats'
Roche, M,O'Connor, E,Diskin, C,Finn, DP (2007) 'The effect of CB1 receptor antagonism in the right basolateral amygdala on conditioned fear and associated analgesia in rats'. European Journal Of Neuroscience, 26 :2643-2653 [DOI] [Details]
(2007) 'The effect of CB1 receptor antagonism in the right basolateral amygdala on conditioned fear and associated analgesia in rats'
Roche M, O’Connor E, Diskin C, Finn DP. (2007) 'The effect of CB1 receptor antagonism in the right basolateral amygdala on conditioned fear and associated analgesia in rats'. European Journal Of Neuroscience, 26 (9):2643-2653 [DOI] [Details]
(2007) 'Supraspinal sites and mechanisms mediating the effects of cannabinoids on pain: the role of GABA and glutamate'
Rea K, Roche M, Finn DP (2007) 'Supraspinal sites and mechanisms mediating the effects of cannabinoids on pain: the role of GABA and glutamate'. British Journal Of Pharmacology, 152 (2):267-286 [DOI] [Details]
(2006) 'Cannabinoid receptor-mediated modulation of lipopolysaccharide-induced alterations in brain and peripheral cytokine levels, circulating lymphocytes and hypothalamo-pituitary-adrenal axis activity in rats in vivo'
Roche, M., Diamond, M., Kelly, J. P. & Finn, D. P. (2006) 'Cannabinoid receptor-mediated modulation of lipopolysaccharide-induced alterations in brain and peripheral cytokine levels, circulating lymphocytes and hypothalamo-pituitary-adrenal axis activity in rats in vivo'. Journal of Neuroimmunology, 181 (1-2):57-67 [DOI] [Details]
(2006) 'Resiniferatoxin'
Finn DP. (2006) 'Resiniferatoxin'. Xpharm, [Details]
(2006) 'Capsazepine'
Finn DP. (2006) 'Capsazepine'. xPharm, [DOI] [Details]
(2006) 'In vivo modulation of LPS-induced alterations in brain and peripheral cytokines and HPA axis activity by cannabinoids'
Roche, M,Diamond, M,Kelly, JP,Finn, DP (2006) 'In vivo modulation of LPS-induced alterations in brain and peripheral cytokines and HPA axis activity by cannabinoids'. Journal Of Neuroimmunology, 181 :57-67 [DOI] [Details]
(2006) 'Behavioral central monoaminergic and hypothalamo-pituitary-adrenal axis correlates of fear-conditioned analgesia in rats'
Finn, DP,Jhaveri, MD,Beckett, SRG,Madjd, A,Kendall, DA,Marsden, CA,Chapman, V (2006) 'Behavioral central monoaminergic and hypothalamo-pituitary-adrenal axis correlates of fear-conditioned analgesia in rats'. Neuroscience, 138 :1309-1317 [DOI] [Details]
(2006) 'The effects of inhibition of endocannabinoid degradation on fear-conditioned analgesia in rats'
Ford G, Butler RK, Roche M, Finn DP (2006) 'The effects of inhibition of endocannabinoid degradation on fear-conditioned analgesia in rats'. Journal of Psychopharmacology, 20 (5) [Details]
(2006) 'In vivo modulation of LPS-induced alterations in brain and peripheral cytokines and HPA axis activity by cannabinoids'
Roche M, Diamond M, Kelly JP, Finn DP (2006) 'In vivo modulation of LPS-induced alterations in brain and peripheral cytokines and HPA axis activity by cannabinoids'. Journal Of Neuroimmunology, 181 (1-2):57-67 [DOI] [Details]
(2006) 'N-Arachidonyl Dopamine'
Finn DP. (2006) 'N-Arachidonyl Dopamine'. Xpharm, [Details]
(2005) 'Comparison of responses of ventral posterolateral and posterior complex thalamic neurones in naive rats and rats with hindpaw inflammation: mu opioid receptor mediated inhibitions'
Abdul Aziz A.A., Finn D.P., Mason R. and Chapman V. (2005) 'Comparison of responses of ventral posterolateral and posterior complex thalamic neurones in naive rats and rats with hindpaw inflammation: mu opioid receptor mediated inhibitions'. NEUROPHARMACOLOGY, 48 (4):607-616 [Details]
(2004) 'TRPV2 (VRL-1) Vanilloid Receptor'
Finn DP (2004) 'TRPV2 (VRL-1) Vanilloid Receptor'. Xpharm, [Details]
(2004) 'Vanilloid Receptors'
Finn DP (2004) 'Vanilloid Receptors'. Xpharm, [Details]
(2004) 'I-2 Imidazoline Receptor'
Finn DP. (2004) 'I-2 Imidazoline Receptor'. Xpharm, [Details]
(2004) 'TRPV1 (VR-1) Vanilloid Receptor'
Finn DP (2004) 'TRPV1 (VR-1) Vanilloid Receptor'. Xpharm, [Details]
(2004) 'Cannabinoids modulate ultrasound-induced aversive responses in rats'
Finn, D. P., Jhaveri, M. D., Beckett, S. R. G., Kendall, D. A., Marsden, C. A. and Chapman, V. (2004) 'Cannabinoids modulate ultrasound-induced aversive responses in rats'. Psychopharmacology, 172 (1):41-51 [Details]
(2004) 'Cannabinoids as analgesic agents: evidence from in vivo studies'
Finn DP and Chapman V (2004) 'Cannabinoids as analgesic agents: evidence from in vivo studies'. Current Neuropharmacology, 2 (1):75-89 [Details]
(2004) 'I-1 Imidazoline Receptor'
Finn DP. (2004) 'I-1 Imidazoline Receptor'. Xpharm, [DOI] [Details]
(2004) 'Imidazoline2 (I2) receptor- and a2-adrenoceptor-mediated modulation of hypothalamo-pituitary-adrenal axis activity in control and acute restraint stressed rats'
Finn DP, Hudson AL, Kinoshita H, Coventry TL, Jessop DS, Nutt DJ and Harbuz MS (2004) 'Imidazoline2 (I2) receptor- and a2-adrenoceptor-mediated modulation of hypothalamo-pituitary-adrenal axis activity in control and acute restraint stressed rats'. Journal of Psychopharmacology, 18 (1):47-53 [Details]
(2004) 'Imidazoline Receptors'
Finn DP (2004) 'Imidazoline Receptors'. Xpharm, [Details]
(2004) 'Effects of the selective 5-HT6 receptor antagonist SB-271046 on nociceptive behaviour and HPA axis activity in rats'
Finn DP, Beckett SRG, Fone KCF, Baxter JA, Ansell L, Marsden CA, Chapman V ( (2004) 'Effects of the selective 5-HT6 receptor antagonist SB-271046 on nociceptive behaviour and HPA axis activity in rats'. Journal of Psychopharmacology, 18 (3) [Details]
(2004) 'Evidence for differential modulation of conditioned aversion and fear-conditioned analgesia by CB1 receptors'
Finn, D. P., Beckett, S. R. G., Richardson, D., Kendall, D. A., Marsden, C. A. & Chapman, V. (2004) 'Evidence for differential modulation of conditioned aversion and fear-conditioned analgesia by CB1 receptors'. European Journal Of Neuroscience, 20 (3):848-852 [Details]
(2004) 'Effects of co-administration of cannabinoids and morphine on nociceptive behaviour, brain monoamines and HPA axis activity in a rat model of persistent pain'
Finn DP, Beckett SRG, Roe CH, Madjd A, Fone KCF, Kendall DA, Marsden CA and Chapman V (2004) 'Effects of co-administration of cannabinoids and morphine on nociceptive behaviour, brain monoamines and HPA axis activity in a rat model of persistent pain'. European Journal of Neuroscience, 19 (3):678-686 [Details]
(2003) 'Effects of direct periaqueductal grey administration of a cannabinoid receptor agonist on nociceptive and aversive responses in rats'
Finn DP, Jhaveri MD, Beckett SRG, Roe CH, Kendall DA, Marsden CA and Chapman V (2003) 'Effects of direct periaqueductal grey administration of a cannabinoid receptor agonist on nociceptive and aversive responses in rats'. Neuropharmacology, 45 (5):594-604 [Details]
(2003) 'Behavioural, neuroendocrine and neurochemical effects of the imidazoline I2 receptor selective ligand BU224 in naïve rats and rats exposed to the stress of the forced swim test'
Finn DP, Martí O, Harbuz MS, Vallès A, Belda X, Márquez C, Jessop DS, Lalies MD, Armario A, Nutt DJ and Hudson AL (2003) 'Behavioural, neuroendocrine and neurochemical effects of the imidazoline I2 receptor selective ligand BU224 in naïve rats and rats exposed to the stress of the forced swim test'. Psychopharmacology, 162 (2):195-202 [Details]
(2003) 'Analgesic effects of cannabinoids: sites and mechanisms of action'
Chapman V and Finn DP (2003) 'Analgesic effects of cannabinoids: sites and mechanisms of action'. Reviews in Analgesia, 7 (1):25-39 [Details]
(2003) 'Novel ligands for the investigation of imidazoline receptors and their binding proteins'
Hudson AL, Tyacke RJ, Lalies MD, Davies N, Finn DP, Martí O, Robinson E, Husbands S, Minchin MCW, Kimura A and Nutt DJ (2003) 'Novel ligands for the investigation of imidazoline receptors and their binding proteins'. Annals of the New York Academy of Sciences, 1009 :302-308 [Details]
(2003) 'The role of the central nucleus of the amygdala in nociception and aversion'
Finn DP, Chapman V, Jhaveri MD, Samanta S, Manders T, Bowden J, Matthews L, Marsden CA and Beckett SRG (2003) 'The role of the central nucleus of the amygdala in nociception and aversion'. Neuroreport, 14 (7):981-984 [Details]
(2002) 'Imidazoline (I2) binding site- and a2-adrenoceptor-mediated modulation of central noradrenergic and HPA axis function in control rats and chronically stressed rats with adjuvant-induced arthritis'
Finn DP, Hudson AL, Lalies ML, Harbuz MS and Nutt DJ (2002) 'Imidazoline (I2) binding site- and a2-adrenoceptor-mediated modulation of central noradrenergic and HPA axis function in control rats and chronically stressed rats with adjuvant-induced arthritis'. Neuropharmacology, 42 (7):958-965 [Details]
(2001) 'Acetaldehyde, a metabolite of ethanol, activates the hypothalamo-pituitary-adrenal axis in the rat'
Kinoshita H, Jessop DS, Finn DP, Coventry TL, Roberts DJ, Ameno K, Ijiri I and Harbuz MS (2001) 'Acetaldehyde, a metabolite of ethanol, activates the hypothalamo-pituitary-adrenal axis in the rat'. Alcohol & Alcoholism, 36 (1):59-64 [Details]
(2001) 'Endomorphins and activation of the hypothalamo-pituitary-adrenal axis'
Coventry TL, Jessop DS, Finn DP, Crabb MD, Kinoshita H and Harbuz MS (2001) 'Endomorphins and activation of the hypothalamo-pituitary-adrenal axis'. Journal of Endocrinology, 169 :185-193 [Details]
(2000) 'Hypothalamo-pituitary-adrenal axis activation by administration of cyanamide: a potent inhibitor of aldehyde dehydrogenase'
Kinoshita H, Harbuz MS, Jessop DS, Finn DP, Ameno K, Ameno S, Kubata T and Ijiri I (2000) 'Hypothalamo-pituitary-adrenal axis activation by administration of cyanamide: a potent inhibitor of aldehyde dehydrogenase'. Forensic Science International, 113 :397-402 [Details]
(2000) 'Cyanamide-induced activation of the hypothalamo-pituitary-adrenal axis'
Kinoshita H, Jessop DS, Finn DP and Harbuz MS (2000) 'Cyanamide-induced activation of the hypothalamo-pituitary-adrenal axis'. Journal of Neuroendocrinology, 12 (3):255-262 [Details]
(2000) 'Acute ethanol decreases NPY mRNA but not POMC mRNA in the arcuate nucleus'
Kinoshita H, Jessop DS, Finn DP, Coventry TL, Roberts DJ, Ameno K, Ijiri I. and Harbuz MS ( (2000) 'Acute ethanol decreases NPY mRNA but not POMC mRNA in the arcuate nucleus'. Neuroreport, 11 (16):3517-3519 [Details]
(1998) 'Acute 3,4-methylenedioxymethamphetamine (MDMA) administration produces a rapid and sustained suppression of immune function in the rat'
Connor, TJ,McNamara, MG,Finn, D,Currid, A,O'Malley, M,Redmond, AM,Kelly, JP,Leonard, BE (1998) 'Acute 3,4-methylenedioxymethamphetamine (MDMA) administration produces a rapid and sustained suppression of immune function in the rat'. Immunopharmacology, 38 :253-260 [Details]

Book Chapters

  Year Publication
(2015) 'Cannabinoids in Parkinson’s disease'
Concannon RM, Finn DP, Dowd E. (2015) 'Cannabinoids in Parkinson’s disease' In: Cannabinoids in Neurological and Mental Disease. USA: Elsevier. [Details]
(2014) 'Neurobiology of stress-induced hyperalgesia'
Finn DP and Olango WM (2014) 'Neurobiology of stress-induced hyperalgesia' In: Behavioral Neurobiology of Chronic Pain - Current Topics in Neurobiology. Germany: Springer. [Details]
(2013) 'Affective and Cognitive Modulation of Pain'
Olango WM and Finn DP (2013) 'Affective and Cognitive Modulation of Pain' In: Pain Therapeutics: Current and Future Treatment Paradigms. London: Royal Society of Chemistry Publishing. [Details]
(2009) 'The Role of Supraspinal GABA and Glutamate in the Mediation and Modulation of Pain'
Rea K and Finn DP (2009) 'The Role of Supraspinal GABA and Glutamate in the Mediation and Modulation of Pain' In: Acute Pain: Causes, Effects and Treatment. Editors: Sam D'Alonso and Katherine L. Grasso © 2009 Nova Science Publishers, Inc. New York, USA: Nova Science Publishers, Inc. [Details]

Edited Books

  Year Publication
(2014) Behavioral Neurobiology of Chronic Pain - Current Topics in Behavioral Neuroscience.
Bradley K Taylor and David P. Finn (Ed.). (2014) Behavioral Neurobiology of Chronic Pain - Current Topics in Behavioral Neuroscience. Germany: Springer. [Details]

Editorial

  Year Publication
(2014) An apPEAling new therapeutic for ulcerative colitis?.
McKernan, DP,Finn, DP (2014) An apPEAling new therapeutic for ulcerative colitis?. Editorial [DOI] [Details]
(2014) Cannabinoids: clearing the smoke on pain, inflammation and neurodegeneration.
Downer, EJ,Finn, DP (2014) Cannabinoids: clearing the smoke on pain, inflammation and neurodegeneration. Editorial [DOI] [Details]
(2012) The endocannabinoid system and emotional processing: pathophysiology and therapeutic potential.
Finn, DP,Viveros, MP,Marco, EM (2012) The endocannabinoid system and emotional processing: pathophysiology and therapeutic potential. Editorial [DOI] [Details]
(2010) International Cannabinoid Research Society-20th Annual Symposium.
Finn, DP (2010) International Cannabinoid Research Society-20th Annual Symposium. Editorial [Details]

Letter

  Year Publication
(2009) Comments on stress-induced analgesia. Response to the Letter to the Editor by Daniel Le Bars and Pascal Carrive on clinical correlates of stress-induced analgesia: Evidence from pharmacological studies.
Ford, GK,Finn, DP (2009) Comments on stress-induced analgesia. Response to the Letter to the Editor by Daniel Le Bars and Pascal Carrive on clinical correlates of stress-induced analgesia: Evidence from pharmacological studies. Letter [DOI] [Details]

Reviews

  Year Publication
(2015) Experimental pain processing in individuals with cognitive impairment: current state of the science.
Defrin, R,Amanzio, M,de Tommaso, M,Dimova, V,Filipovic, S,Finn, DP,Gimenez-Llort, L,Invitto, S,Jensen-Dahm, C,Lautenbacher, S,Oosterman, JM,Petrini, L,Pick, CG,Pickering, G,Vase, L,Kunz, M (2015) Experimental pain processing in individuals with cognitive impairment: current state of the science. Reviews [DOI] [Details]
(2014) Stress-induced hyperalgesia.
Jennings, EM,Okine, BN,Roche, M,Finn, DP (2014) Stress-induced hyperalgesia. Reviews [DOI] [Details]
(2014) Cognition and pain.
Moriarty, O,Finn, DP (2014) Cognition and pain. Reviews [DOI] [Details]
(2012) PHARMACOLOGICAL INHIBITION OF ENDOCANNABINOID DEGRADATION MODULATES THE EXPRESSION OF INFLAMMATORY MEDIATORS IN THE HYPOTHALAMUS FOLLOWING AN IMMUNOLOGICAL STRESSOR.
Kerr, DM,Burke, NN,Ford, GK,Connor, TJ,Harhen, B,Egan, LJ,Finn, DP,Roche, M (2012) PHARMACOLOGICAL INHIBITION OF ENDOCANNABINOID DEGRADATION MODULATES THE EXPRESSION OF INFLAMMATORY MEDIATORS IN THE HYPOTHALAMUS FOLLOWING AN IMMUNOLOGICAL STRESSOR. Reviews [DOI] [Details]
(2011) The effect of pain on cognitive function: A review of clinical and preclinical research.
Moriarty, O,McGuire, BE,Finn, DP (2011) The effect of pain on cognitive function: A review of clinical and preclinical research. Reviews [DOI] [Details]
(2010) Brain CB2 receptors: Implication for Neuropsychiatric disorders.
Roche M, Finn DP (2010) Brain CB2 receptors: Implication for Neuropsychiatric disorders. Reviews [Details]
(2010) International Cannabinoid Research Society - 20th Annual Symposium.
Finn DP (2010) International Cannabinoid Research Society - 20th Annual Symposium. Reviews [Details]
(2010) European College of Neuropsychopharmacology (ECNP) - 23rd Congress.
Finn,D.P. (2010) European College of Neuropsychopharmacology (ECNP) - 23rd Congress. Reviews [Details]
(2009) Report on ECNP Targeted Expert Meeting.
Finn, D. Eds A.C.E. Linthorst and D.S. Baldwin (2009) Report on ECNP Targeted Expert Meeting. Istanbul, Turkey: Reviews [Details]
(2009) 6-iodonordihydrocapsaicin.
Roche M, Finn DP (2009) 6-iodonordihydrocapsaicin. Reviews [DOI] [Details]
(2009) Modulation of stress by imidazoline binding sites: Implications for psychiatric disorders.
Smith, KL,Jessop, DS,Finn, DP (2009) Modulation of stress by imidazoline binding sites: Implications for psychiatric disorders. Reviews [DOI] [Details]
(2009) Stress-induced analgesia.
Butler, RK,Finn, DP (2009) Stress-induced analgesia. Reviews [DOI] [Details]
(2008) Clinical correlates of stress-induced analgesia: Evidence from pharmacological studies.
Ford, GK,Finn, DP (2008) Clinical correlates of stress-induced analgesia: Evidence from pharmacological studies. Reviews [DOI] [Details]
(2007) Supraspinal modulation of pain by cannabinoids: the role of GABA and glutamate.
Rea, K,Roche, M,Finn, DP (2007) Supraspinal modulation of pain by cannabinoids: the role of GABA and glutamate. Reviews [DOI] [Details]
(2007) Supraspinal sites and mechanisms mediating the effects of cannabinoids on pain: the role of GABA and glutamate. British Journal of Pharmacology.
Rea K, Roche M, Finn DP. (2007) Supraspinal sites and mechanisms mediating the effects of cannabinoids on pain: the role of GABA and glutamate. British Journal of Pharmacology. Reviews [Details]
(2004) International Cannabinoid Research Society - 14th Annual Symposium.
Finn DP (2004) International Cannabinoid Research Society - 14th Annual Symposium. Reviews [Details]
(2004) International Cannabinoid Research Society -.
Finn,D.P. (2004) International Cannabinoid Research Society -. Reviews [Details]
(2004) British Association for Psychopharmacology Annual Meeting.
Finn,D.P. (2004) British Association for Psychopharmacology Annual Meeting. Reviews [Details]

Honours and Awards

  Year Title Awarding Body
2009 Outstanding Young Person of the Year (TOYP) award from Junior Chamber International Ireland in the Scientific Development Category Junior Chamber International Ireland
2006 Wyeth Award for Outstanding Research in Preclinical Psychopharmacology by the British Association for Psychopharmacology British Association for Psychopharmacology
2006 Pain Research Medal Irish Pain Society
2005 SFI President of Ireland Young Researcher Award

Professional Associations

  Association Function From / To
Royal Academy of Medicine in Ireland Council Member- Biomedical Sciences Section /
Irish Pain Society President-Elect /
International Association for the Study of Pain Full Member /
Neuroscience Ireland Council member /
European College of Neuropsychopharmacology Full member and Scientific Advisory Panel Member /
The British Pharmacological Society Full member /
International Cannabinoid Research Society Full Member 01-JAN-05 /

Committees

  Committee Function From / To
Royal Academy of Medicine in Ireland, Biomedical Sciences Section Council Member 01-JUL-05 /
Irish Pain Society Committee member /
Neuroscience Ireland Council member /
European College of Neuropsychopharmacology Scientific Advisory Panel for Anxiety and Anxiolytics Panel member /

Other Activities

  Description

2010-2012: Member of the Editorial Board of Journal of PsychopharmacologyPeer reviewer: I am regularly invited to review research papers for a number of international journals including Journal of Neuroscience, European Journal of Neuroscience, Neuropsychopharmacology, British Journal of Pharmacology, Neuropharmacology, Neuroscience, Brain Research, Biological Psychiatry, Developmental Neurobiology, Neuroscience Letters, Canadian Journal of Physiology and Pharmacology, Pharmacology, Biochemistry and Behavior, Journal of Psychopharmacology, Pain, European Journal of Pain, European Journal of Pharmacology, Anesthesia and Analgesia, Psychoneuroendocrinology, Neuroscience and Biobehavioral reviews, Acta Neuropsychiatrica Invited to review grant proposals for the UK Biotechnology and Biological Sciences Research Council, The UK Medical Research Council, The Wellcome Trust and Science Foundation Ireland Abstract/poster review for European College of Neuropsychopharmacology, European Cannabinoid Research Workshop, Neuroscience Ireland and Royal Academy of Medicine in Ireland Biomedical Section