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Courses
Courses
Choosing a course is one of the most important decisions you'll ever make! View our courses and see what our students and lecturers have to say about the courses you are interested in at the links below.
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University Life
University Life
Each year more than 4,000 choose NUI Galway as their University of choice. Find out what life at NUI Galway is all about here.
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About NUI Galway
About NUI Galway
Since 1845, NUI Galway has been sharing the highest quality teaching and research with Ireland and the world. Find out what makes our University so special – from our distinguished history to the latest news and campus developments.
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Colleges & Schools
Colleges & Schools
NUI Galway has earned international recognition as a research-led university with a commitment to top quality teaching across a range of key areas of expertise.
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Research & Innovation
Research & Innovation
NUI Galway’s vibrant research community take on some of the most pressing challenges of our times.
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Business & Industry
Guiding Breakthrough Research at NUI Galway
We explore and facilitate commercial opportunities for the research community at NUI Galway, as well as facilitating industry partnership.
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Alumni, Friends & Supporters
Alumni, Friends & Supporters
There are over 90,000 NUI Galway graduates Worldwide, connect with us and tap into the online community.
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Community Engagement
Community Engagement
At NUI Galway, we believe that the best learning takes place when you apply what you learn in a real world context. That's why many of our courses include work placements or community projects.
Natural Sciences
Dr. Muriel Grenon
Biography
Research Interests
Research Projects
Project | Start Date | End Date | |
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CELL EXPLORERS | 01-JAN-19 | 31-DEC-20 | |
CELL EXPLORERS - NATIONAL EXPANSION FOR A SUSTAINABLE PUBLIC ENGAGEMENT MODEL | 01-JAN-17 | 30-APR-22 | |
Cell EXPLORERS - national expansion of a sustainable public engagement model | 01-JAN-15 | 16-JAN-18 | |
”Creation of a student‐led primary school outreach activity in Cellular Biology and Biotechnology” | 01-FEB-12 | 30-NOV-12 | |
“Conservation of the tumor suppressor ING2 functions in the eukaryotic DNA damage response” | 01-JAN-12 | 31-AUG-12 | |
Eukaryotic response to DNA damage | 01-APR-08 | 31-MAR-13 | |
“Study of histones H3 and H4 post-translational modifications in Rad9 recruitment to chromatin as an early step of DNA damage checkpoint activation” | 01-OCT-05 | 30-SEP-08 |
Peer Reviewed Journals
Year | Publication | |
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(2019) | 'ING3 is required for ATM signaling and DNA repair in response to DNA double strand breaks'
Mouche, A;Archambeau, J;Ricordel, C;Chaillot, L;Bigot, N;Guillaudeux, T;Grenon, M;Pedeux, R (2019) 'ING3 is required for ATM signaling and DNA repair in response to DNA double strand breaks'. Cell Death And Differentiation, 26 :2344-2357 [DOI] [Details] |
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(2016) | 'Researchers: share your passion for science!'
Concannon, C,Grenon, M (2016) 'Researchers: share your passion for science!'. Biochemical Society Transactions, 44 :1507-1515 [DOI] [Details] |
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(2013) | 'Site-Specific Phosphorylation of the DNA Damage Response Mediator Rad9 by Cyclin-Dependent Kinases Regulates Activation of Checkpoint Kinase 1'
Abreu, CM,Kumar, R,Hamilton, D,Dawdy, AW,Creavin, K,Eivers, S,Finn, K,Balsbaugh, JL,O'Connor, R,Kiely, PA,Shabanowitz, J,Hunt, DF,Grenon, M,Lowndes, NF (2013) 'Site-Specific Phosphorylation of the DNA Damage Response Mediator Rad9 by Cyclin-Dependent Kinases Regulates Activation of Checkpoint Kinase 1'. Plos Genetics, 9 (4) [DOI] [Details] |
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(2011) | 'Regulation of the DNA damage response and gene expression by the Dot1L histone methyltransferase and the 53Bp1 tumour suppressor'
FitzGerald J, Moureau S, Drogaris P, O'Connell E, Abshiru N, Verreault A, Thibault P, Grenon M, Lowndes NF. (2011) 'Regulation of the DNA damage response and gene expression by the Dot1L histone methyltransferase and the 53Bp1 tumour suppressor'. Plos One, 6 (2) [DOI] [Details] |
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(2011) | 'Eukaryotic DNA damage checkpoint activation in response to double-strand breaks'
Finn K, Lowndes NF, Grenon M (2011) 'Eukaryotic DNA damage checkpoint activation in response to double-strand breaks'. Life Sciences, [DOI] [Details] |
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(2010) | 'Dynamics of Rad9 Chromatin Binding and Checkpoint Function Are Mediated by Its Dimerization and Are Cell Cycle-Regulated by CDK1 Activity'
Granata, M;Lazzaro, F;Novarina, D;Panigada, D;Puddu, F;Abreu, CM;Kumar, R;Grenon, M;Lowndes, NF;Plevani, P;Muzi-Falconi, M (2010) 'Dynamics of Rad9 Chromatin Binding and Checkpoint Function Are Mediated by Its Dimerization and Are Cell Cycle-Regulated by CDK1 Activity'. Plos Genetics, 6 [DOI] [Details] |
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(2010) | 'MRN and the race to the break'
Rupnik A, Lowndes NF, Grenon M (2010) 'MRN and the race to the break'. Chromosoma, 119 (2):115-135 [DOI] [Details] |
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(2009) | '53BP1: function and mechanisms of focal recruitment'
FitzGerald JE, Grenon M, Lowndes NF (2009) '53BP1: function and mechanisms of focal recruitment'. Biochemical Society Transactions, 37 (Pt 4):897-904 [DOI] [Details] |
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(2008) | 'Transcriptional response of Candida parapsilosis following exposure to farnesol (vol 51, pg 2304, 2007)'
Rossignol, T;Logue, ME;Reynolds, K;Grenon, M;Lowndes, NF;Butler, G (2008) 'Transcriptional response of Candida parapsilosis following exposure to farnesol (vol 51, pg 2304, 2007)'. Antimicrobial Agents And Chemotherapy, 52 :2296-2296 [DOI] [Details] |
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(2008) | 'Quick Guide: The MRN complex'
Rupnik A, Grenon M, Lowndes NF (2008) 'Quick Guide: The MRN complex'. Curr Biol, 18 (11):455-457 [Details] |
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(2008) | 'The MRN complex'
Rupnik A, Grenon M, Lowndes N (2008) 'The MRN complex'. Current Biology, 18 (11):1-7 [DOI] [Details] |
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(2003) | 'The budding yeast Rad9 checkpoint complex: chaperone proteins are required for its function'
Gilbert, CS;van den Bosch, M;Green, CM;Vialard, JE;Grenon, M;Erdjument-Bromage, H;Tempst, P;Lowndes, NF (2003) 'The budding yeast Rad9 checkpoint complex: chaperone proteins are required for its function'. Embo Reports, 4 :953-958 [DOI] [Details] |
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(2007) | 'Transcriptional response of Candida parapsilosis following exposure to farnesol'
Rossignol, T,Logue, ME,Reynolds, K,Grenon, M,Lowndes, NF,Butler, G (2007) 'Transcriptional response of Candida parapsilosis following exposure to farnesol'. Antimicrobial Agents And Chemotherapy, 51 :2304-2312 [DOI] [Details] |
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(2007) | 'Docking onto chromatin via the Saccharomyces cerevisiae Rad9 Tudor domain'
Grenon, M,Costelloe, T,Jimeno, S,O'Shaughnessy, A,FitzGerald, J,Zgheib, O,Degerth, L,Lowndes, NF (2007) 'Docking onto chromatin via the Saccharomyces cerevisiae Rad9 Tudor domain'. Yeast, 24 :105-119 [DOI] [Details] |
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(2006) | 'Histone H2A phosphorylation and H3 methylation are required for a novel Rad9 DSB repair function following checkpoint activation'
G. Toh, A. O’Shaughnessy, S. Jimeno, I. Dobbie, M. Grenon, S. Maffini S, A. O' Rorke and NF. Lowndes (2006) 'Histone H2A phosphorylation and H3 methylation are required for a novel Rad9 DSB repair function following checkpoint activation'. Dna Repair Amst, 5 [Details] |
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(2006) | 'Double-strand breaks trigger MRX- and Mec1-dependent, but Tel1-independent, checkpoint activation'
Grenon, M,Magill, CP,Lowndes, NF,Jackson, SP (2006) 'Double-strand breaks trigger MRX- and Mec1-dependent, but Tel1-independent, checkpoint activation'. Fems Yeast Research, 6 :836-847 [DOI] [Details] |
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(2006) | 'Multiple approaches to study S. cerevisiae Rad9, a prototypical checkpoint protein'
O'Shaughnessy AM, Grenon M, Gilbert C, Toh GW, Green CM, Lowndes NF (2006) 'Multiple approaches to study S. cerevisiae Rad9, a prototypical checkpoint protein'. Methods Enzymol, 409 :131-150 [DOI] [Details] |
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(2003) | 'The budding yeast Rad9 checkpoint complex: chaperone proteins are required for its function'
• C. Gilbert, M. van den Bosch, C. Green, J.Vialard, M. Grenon, H. Erdjument-Bromage, P. Tempst and N. Lowndes (2003) 'The budding yeast Rad9 checkpoint complex: chaperone proteins are required for its function'. Embo Reports, 4 [Details] |
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(2002) | 'Fission yeast chk1 mutants show distinct responses to different types of DNA damaging treatments'
Francesconi S, Smeets M, Grenon M, Tillit J, Blaisonneau J, Baldacci G (2002) 'Fission yeast chk1 mutants show distinct responses to different types of DNA damaging treatments'. Gene, 7 (7):663-673 [Details] |
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(2001) | 'Checkpoint activation in response to double-strand breaks requires the Mre11/Rad50/Xrs2 complex'
Grenon, M,Gilbert, C,Lowndes, NF (2001) 'Checkpoint activation in response to double-strand breaks requires the Mre11/Rad50/Xrs2 complex'. Nature Cell Biology, 3 :844-847 [Details] |
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(2001) | 'Topoisomerase III acts upstream of Rad53p in the S-phase DNA damage checkpoint'
Chakraverty RK, Kearsey JM, Oakley TJ, Grenon M, de La Torre Ruiz MA, Lowndes NF, Hickson ID (2001) 'Topoisomerase III acts upstream of Rad53p in the S-phase DNA damage checkpoint'. Molecular And Cellular Biology, 21 (21):7150-7162 [DOI] [Details] |
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(1999) | 'The S/M checkpoint at 37 degrees C and the recovery of viability of the mutant poldeltats3 require the crb2+/rhp9+ gene in fission yeast'
Grenon M, Tillit J, Piard K, Baldacci G, Francesconi S (1999) 'The S/M checkpoint at 37 degrees C and the recovery of viability of the mutant poldeltats3 require the crb2+/rhp9+ gene in fission yeast'. Molecular & General Genetics, 260 (6):522-534 [Details] |
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(1997) | 'PCNA and DNA polymerase delta catalytic subunit from Schizosaccharomyces pombe do not interact directly'
Tratner I, Piard K, Grenon M, Perderiset M, Baldacci G (1997) 'PCNA and DNA polymerase delta catalytic subunit from Schizosaccharomyces pombe do not interact directly'. Biochem, 231 (2):321-328 [DOI] [Details] |
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(1997) | 'p56(chk1) protein kinase is required for the DNA replication checkpoint at 37 degrees C in fission yeast'
Francesconi S, Grenon M, Bouvier D, Baldacci G (1997) 'p56(chk1) protein kinase is required for the DNA replication checkpoint at 37 degrees C in fission yeast'. Embo Journal, 16 (6):1332-1341 [DOI] [Details] |
Conference Publications
Year | Publication | |
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(2018) | Investigating the effect of scientist demonstrators on primary children’s science self-efficacy
Carroll, S., McCauley, V. & Grenon, M. (2018) Investigating the effect of scientist demonstrators on primary children’s science self-efficacy Investigating the effect of scientist demonstrators on primary children’s science self-efficacy [Details] |
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(2016) | 7th International Conference on Software Development and Technologies for Enhancing Accessibility and Fighting Info-exclusion
• P. Charlton, A. Preston, C. Karagiannidis, C. Kouroupetroglou, M. Grenon, S. Handschuh, A. Koumpis (2016) Use of the Curiosity Cabinet metaphor to support inclusive learning 7th International Conference on Software Development and Technologies for Enhancing Accessibility and Fighting Info-exclusion [DOI] [Details] |
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(2009) | 53BP1: function and mechanisms of focal recruitment
FitzGerald, JE,Grenon, M,Lowndes, NF (2009) BIOCHEMICAL SOCIETY TRANSACTIONS 53BP1: function and mechanisms of focal recruitment , pp.897-904 [DOI] [Details] |
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(2009) | BIOCHEMICAL SOCIETY TRANSACTIONS
FitzGerald, JE;Grenon, M;Lowndes, NF (2009) 53BP1: function and mechanisms of focal recruitment BIOCHEMICAL SOCIETY TRANSACTIONS , pp.897-904 [DOI] [Details] |
Abstract
Year | Publication | |
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(2015) | The tumor suppressive protein ING3, a new player in the maintenance of genome stability.
Mouche, A,Guerillon, C,Bigot, N,Le Guevel, R,Guillaudeux, T,Grenon, M,Pedeux, R (2015) The tumor suppressive protein ING3, a new player in the maintenance of genome stability. Abstract [Details] |
Conference Paper
Year | Publication | |
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(2019) | ‘A Scientist knows what s/he’s doing’: Exploring the effect of Scientist-Led Outreach on Primary Children’s Science Self-Efficacy Beliefs.
Carroll, S., McCauley, V. and Grenon, M. (2019) ‘A Scientist knows what s/he’s doing’: Exploring the effect of Scientist-Led Outreach on Primary Children’s Science Self-Efficacy Beliefs. Conference Paper [Details] |
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(2018) | Investigating the effect of scientist demonstators on primary children’s science self-efficacy. The International Conference ‘New Perspectives in Science Education’. Florence on 22-23 March 2018.
Carroll, S., McCauley, V. & Grenon, M. (2018) Investigating the effect of scientist demonstators on primary children’s science self-efficacy. The International Conference ‘New Perspectives in Science Education’. Florence on 22-23 March 2018. Conference Paper [Details] |
Conference Poster
Year | Publication | |
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(2018) | Measuring primary children’s confidence in science’. Poster. Scientix Conference, Brussels, Belgium, 22-23 March 2018.
Carroll, S., McCauley, V. and Grenon, M. (2018) Measuring primary children’s confidence in science’. Poster. Scientix Conference, Brussels, Belgium, 22-23 March 2018. Conference Poster [Details] |
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(2019) | Validation of a ‘Sources of Science Self-Efficacy’ Scale adapted for Primary Children for the Informal Science Context. Poster. Conference of the European Science Education Research Association (ESERA), Bologna, Italy, 26-30 August 2019.
Carroll, S., McCauley, V. and Grenon, M. (2019) Validation of a ‘Sources of Science Self-Efficacy’ Scale adapted for Primary Children for the Informal Science Context. Poster. Conference of the European Science Education Research Association (ESERA), Bologna, Italy, 26-30 August 2019. Conference Poster [Details] |
Correction
Year | Publication | |
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(2008) | Transcriptional response of Candida parapsilosis following exposure to farnesol (vol 51, pg 2304, 2007).
Rossignol, T,Logue, ME,Reynolds, K,Grenon, M,Lowndes, NF,Butler, G (2008) Transcriptional response of Candida parapsilosis following exposure to farnesol (vol 51, pg 2304, 2007). Correction [DOI] [Details] |
Editorial
Year | Publication | |
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(2008) | The MRN complex.
Rupnik, A;Grenon, M;Lowndes, N (2008) The MRN complex. CAMBRIDGE: Editorial [Details] |
Reviews
Year | Publication | |
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(2010) | MRN and the race to the break.
Rupnik, A;Lowndes, NF;Grenon, M (2010) MRN and the race to the break. NEW YORK: Reviews [DOI] [Details] |
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(2012) | Eukaryotic DNA damage checkpoint activation in response to double-strand breaks.
Finn, K;Lowndes, NF;Grenon, M (2012) Eukaryotic DNA damage checkpoint activation in response to double-strand breaks. BASEL: Reviews [DOI] [Details] |
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(2016) | Researchers: share your passion for science!.
Concannon, C;Grenon, M (2016) Researchers: share your passion for science!. LONDON: Reviews [DOI] [Details] |
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(2012) | Eukaryotic DNA damage checkpoint activation in response to double-strand breaks.
Finn, K,Lowndes, NF,Grenon, M (2012) Eukaryotic DNA damage checkpoint activation in response to double-strand breaks. Reviews [DOI] [Details] |
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(2010) | MRN and the race to the break.
Rupnik, A,Lowndes, NF,Grenon, M (2010) MRN and the race to the break. Reviews [DOI] [Details] |
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(2009) | 53BP1: Function and Mechanisms of Focal Recruitment. Biochemistry Society Transactions.
FitzGerald J, Grenon M, Lowndes NF (2009) 53BP1: Function and Mechanisms of Focal Recruitment. Biochemistry Society Transactions. Reviews [Details] |
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(2006) | Multiple approaches to study S-cerevisiae Rad9, a prototypical checkpoint protein.
O'Shaughnessy, AM,Grenon, M,Gilbert, C,Toh, GWL,Green, CM,Lowndes, NF (2006) Multiple approaches to study S-cerevisiae Rad9, a prototypical checkpoint protein. Reviews [DOI] [Details] |
Honours and Awards
Year | Title | Awarding Body | |
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2019 | Outstanding contribution to Science communication | Science Foundation Ireland | |
2019 | Chevalier de l'ordre des palmes académiques (Knight of the order of Academic Palms) | French Minister of National Education | |
2017 | NUI Galway President Award for Societal Impact | NUIGalway President | |
2013 | Outstanding Contribution to STEM | Galway Science and Technology Festival |
Committees
Committee | Function | From / To | |
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College of Science STEM Promotion | Committee member | 01-SEP-14 / | |
Galway Science and Technology Forum | Committee member | 01-SEP-14 / | |
University Societies Coordinating Group | Staff representative | 01-SEP-14 / 31-AUG-17 | |
College of Science STEM Promotion | Chair | 01-FEB-17 / 01-JUN-17 |
Education
Year | Institution | Qualification | Subject | |
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2012 | NUI Galway | Postgraduate Certificate in Teaching and Learning | Teaching and learning in Higher education | |
2009 | Paris Sud XI | Habilitation à diriger des recherches | Habilitation à diriger des recherches - Molecular Genetics | |
1998 | Paris Sud XI | PhD | Cellular and Molecular Genetics |
Outreach Activities
Description | |
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SFI Discovering Science and Engineering 2013: The Cell EXPLORERS roadshow |
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Wellcome Trust people award Summer 2013. Cell EXPLORERS, a pilot programme toward sustainable public engagement within universities |
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NUIG EXPLORE programme 2013: ReelLife Science, in collaboration with Dr Enda O'Connell |
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Biochemical Society 2012 - The Cell EXPLORERS show |
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Royal Dublin Society 2012 lecture Bursary - Fantastic DNA! |
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NUIG EXPLORE programme 2012: The Cell EXPLORERS show |
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NUIG EXPLORE programme 2012: Creation of a student-led primary school outreach activity in cellular Biology and Biotechnology |
Community Engagement
Title | Type | From / To | |
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Outreach | NUIG EXPLORE programme 2012: Creation of a student-led primary school outreach | / |
Recent Postgraduate Students
Graduation | Name | Degree | Primary Supervisor | |
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2013 | Mary Walsh | PhD | N | |
2012 | Carla Abreu | PhD | N | |
2011 | Ramesh Kumar | PhD | N | |
2010 | Karen Finn | PhD | N | |
2014 | Karim Mrouj | Msc |
Current Postgraduate Students (Research)
Student | Degree Type | Type | |
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Sarah Carroll | Doctorate - Structured PhD (Science) | Supervisor |
Modules Taught
Term/Year | Module Title | Module Code | Subject / Desc | |
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2013-2015 | Biochemistry for 1st year preclinical students |
Internal Collaborators
Name | Description of Collaboration | |
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Internal Collaborators |
External Collaborators
Name | Organisation / Institute | Country | Description of Collaboration | |
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External Collaborators |