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Natural Sciences

Dr. Muriel Grenon

Ph.D.

Contact Details

Lecturer
Biochemistry
Room 131
Biochemistry
School of Natural Sciences
Art & Science Building
NUI Galway

T: 091495848
E: muriel.grenon@nuigalway.ie
W: www.cellexplorers.com @cellexplorers
 
researcher

Biography

Research Projects

  Project Start Date End Date
Cell EXPLORERS - national expansion of a sustainable public engagement model 01-JAN-15 31-DEC-16
”Creation of a student‐led primary school outreach activity in Cellular Biology and Biotechnology” 01-FEB-12 30-NOV-12
“Conservation of the tumor suppressor ING2 functions in the eukaryotic DNA damage response” 01-JAN-12 31-AUG-12
Eukaryotic response to DNA damage 01-APR-08 31-MAR-13
“Study of histones H3 and H4 post-translational modifications in Rad9 recruitment to chromatin as an early step of DNA damage checkpoint activation” 01-OCT-05 30-SEP-08

Peer Reviewed Journals

  Year Publication
(2013) 'Site-Specific Phosphorylation of the DNA Damage Response Mediator Rad9 by Cyclin-Dependent Kinases Regulates Activation of Checkpoint Kinase 1'
Abreu, CM,Kumar, R,Hamilton, D,Dawdy, AW,Creavin, K,Eivers, S,Finn, K,Balsbaugh, JL,O'Connor, R,Kiely, PA,Shabanowitz, J,Hunt, DF,Grenon, M,Lowndes, NF (2013) 'Site-Specific Phosphorylation of the DNA Damage Response Mediator Rad9 by Cyclin-Dependent Kinases Regulates Activation of Checkpoint Kinase 1'. Plos Genetics, 9 (4) [DOI] [Details]
(2011) 'Eukaryotic DNA damage checkpoint activation in response to double-strand breaks'
Finn K, Lowndes NF, Grenon M (2011) 'Eukaryotic DNA damage checkpoint activation in response to double-strand breaks'. Life Sciences, [DOI] [Details]
(2010) 'MRN and the race to the break'
Rupnik A, Lowndes NF, Grenon M (2010) 'MRN and the race to the break'. Chromosoma, 119 (2):115-135 [DOI] [Details]
(2007) 'Docking onto chromatin via the Saccharomyces cerevisiae Rad9 Tudor domain'
Grenon, M,Costelloe, T,Jimeno, S,O'Shaughnessy, A,FitzGerald, J,Zgheib, O,Degerth, L,Lowndes, NF (2007) 'Docking onto chromatin via the Saccharomyces cerevisiae Rad9 Tudor domain'. Yeast, 24 :105-119 [DOI] [Details]
(2006) 'Double-strand breaks trigger MRX- and Mec1-dependent, but Tel1-independent, checkpoint activation'
Grenon, M,Magill, CP,Lowndes, NF,Jackson, SP (2006) 'Double-strand breaks trigger MRX- and Mec1-dependent, but Tel1-independent, checkpoint activation'. Fems Yeast Research, 6 :836-847 [DOI] [Details]
(2006) 'Multiple approaches to study S. cerevisiae Rad9, a prototypical checkpoint protein'
O'Shaughnessy AM, Grenon M, Gilbert C, Toh GW, Green CM, Lowndes NF (2006) 'Multiple approaches to study S. cerevisiae Rad9, a prototypical checkpoint protein'. Methods Enzymol, 409 :131-150 [DOI] [Details]
(2001) 'Checkpoint activation in response to double-strand breaks requires the Mre11/Rad50/Xrs2 complex'
Grenon, M,Gilbert, C,Lowndes, NF (2001) 'Checkpoint activation in response to double-strand breaks requires the Mre11/Rad50/Xrs2 complex'. Nature Cell Biology, 3 :844-847 [Details]

Honours and Awards

  Year Title Awarding Body
2013 Outstanding Contribution to STEM Galway Science and Technology Festival

Education

  Year Institution Qualification Subject
2012 NUI Galway Postgraduate certificate in Teaching and learning Teaching and learning in Higher education
2009 Paris Sud XI Habilitation Hbailitation a diriger les recherches - Molecular Genetics
1998 Paris Sud XI PhD Cellular and Molecular Genetics

Outreach Activities

  Description

SFI Discovering Science and Engineering 2013: The Cell EXPLORERS roadshow

Wellcome Trust people award Summer 2013. Cell EXPLORERS, a pilot programme toward sustainable public engagement within universities

NUIG EXPLORE programme  2013: ReelLife Science, in collaboration with Dr Enda O'Connell

Biochemical Society 2012 - The Cell EXPLORERS show

Royal Dublin Society 2012 lecture Bursary - Fantastic DNA!

NUIG EXPLORE programme  2012: The Cell EXPLORERS show

NUIG EXPLORE programme  2012: Creation of a student-led primary school outreach activity in cellular Biology and Biotechnology

Recent Postgraduate Students

  Graduation Name Degree Primary Supervisor
2013 Mary Walsh PhD N
2012 Carla Abreu PhD N
2011 Ramesh Kumar PhD N
2010 Karen Finn PhD N

Modules Taught

  Term/Year Module Title Module Code Subject / Desc
2013-2015 Biochemistry for 1st year preclinical students

Internal Collaborators

  Name Description of Collaboration
Internal Collaborators
Andrew Flaus, Centre for Chromosome Biology, School of Natural Sciences, NUI Galway

External Collaborators

  Name Organisation / Institute Country Description of Collaboration
External Collaborators
Remy Pedeux, School of Medicine, Rennes University, France