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Courses
Courses
Choosing a course is one of the most important decisions you'll ever make! View our courses and see what our students and lecturers have to say about the courses you are interested in at the links below.
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University Life
University Life
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About NUI Galway
About NUI Galway
Since 1845, NUI Galway has been sharing the highest quality teaching and research with Ireland and the world. Find out what makes our University so special – from our distinguished history to the latest news and campus developments.
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Colleges & Schools
Colleges & Schools
NUI Galway has earned international recognition as a research-led university with a commitment to top quality teaching across a range of key areas of expertise.
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Research & Innovation
Research & Innovation
NUI Galway’s vibrant research community take on some of the most pressing challenges of our times.
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Business & Industry
Guiding Breakthrough Research at NUI Galway
We explore and facilitate commercial opportunities for the research community at NUI Galway, as well as facilitating industry partnership.
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Alumni, Friends & Supporters
Alumni, Friends & Supporters
There are over 90,000 NUI Galway graduates Worldwide, connect with us and tap into the online community.
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Community Engagement
Community Engagement
At NUI Galway, we believe that the best learning takes place when you apply what you learn in a real world context. That's why many of our courses include work placements or community projects.
Natural Sciences
DR Una FitzGerald
Biography
Research Interests
Research Projects
Project | Start Date | End Date | |
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Engineering Underpinning Medicine | 01-SEP-19 | 31-AUG-24 | |
PMSMatTrain - ESR Account Dr Nathan Quinlan | 01-MAY-19 | 30-APR-23 | |
PMSMatTrain | 01-MAY-19 | 30-APR-23 | |
PMS Mat Train_Additional Funds | 01-MAY-19 | 30-APR-23 | |
PMSMatTrain - ESR Account Prof. Abhay Pandit | 01-MAY-19 | 30-APR-23 | |
****CO-ORDINATOR ACCOUNT**** PMSMatTrain | 01-MAY-19 | 30-APR-23 | |
Development of Biomaterial-based Delivery Systems for Parkinsons disease - an Integrated Pan-European Approach | 01-JAN-16 | 31-DEC-19 | |
GALWAY N KAREN DOYLE | 20-MAY-09 | 31-DEC-20 | |
ELISA | 01-DEC-15 | 01-JUL-16 | |
POLYMER-MEDIATED DELIVERY OF ENDOPLASMIC RETICULUM STRESS-ALTERING SIRNA TO OLIGODENDROCYTES MS IRELAND: HRB (50 :50, ADMIN THROUGH MSI) UNA FITZGERALD | 01-NOV-11 | 30-NOV-15 | |
Multiple Sclerosis Research UNA FITZGERALD 101467 | 01-JAN-11 | 31-JUL-20 | |
IRCSET FELLOWSHIP MARY NI FHLATHARTAIGH UNA FITZGE | 01-OCT-08 | 30-SEP-13 | |
FOUNDATION OFFICE 08-12 MULTIPLE SCLEROSIS RESEARC | 01-JAN-08 | 31-DEC-22 | |
SFI OVERHEADS EQUIPMENT UNA FITZGERALD | 01-JAN-08 | 30-JUN-08 | |
IICN SANOFI-AVENTIS AWARD UNA FITZGERALD | 20-DEC-06 | 07-MAY-08 | |
SFI ENDOPLASMIC RETICULUM STRESS UNA FITZGERALD | 01-MAY-06 | 30-SEP-09 | |
MS AND GENERAL IRL UFITZ UNA FITZGERALD | 01-NOV-05 | 31-DEC-17 | |
MF 2005 MS PATIENTS UNA FITZGERALD | 01-OCT-05 | 30-SEP-06 |
Contract Researchers
Researcher Name | Project | Role | Funding Body | |
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Dr. Jill McMahon | Multiple Sclerosis Research | Senior Researcher | NUI Galway |
Peer Reviewed Journals
Year | Publication | |
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(2020) | 'Dysregulation of astrocytic mitochondrial function following exposure to a dopamine metabolite: Implications for Parkinson's disease'
Bagnoli, E,Diviney, T,FitzGerald, U (2020) 'Dysregulation of astrocytic mitochondrial function following exposure to a dopamine metabolite: Implications for Parkinson's disease'. European Journal Of Neuroscience, [DOI] [Details] |
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(2019) | 'Profile of the unfolded protein response in rat cerebellar cortical development'
Naughton, M;McMahon, J;Healy, S;FitzGerald, U (2019) 'Profile of the unfolded protein response in rat cerebellar cortical development'. The Journal Of Comparative Neurology, 527 [DOI] [Details] |
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(2019) | 'ATPase activity of human binding immunoglobulin protein (BiP) variants is enhanced by signal sequence and physiological concentrations of Mn2+'
Bandla, S,Diaz, S,Nasheuer, HP,FitzGerald, U (2019) 'ATPase activity of human binding immunoglobulin protein (BiP) variants is enhanced by signal sequence and physiological concentrations of Mn2+'. FEBS open bio, [DOI] [Details] |
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(2005) | 'CD95-mediated alteration in Hsp70 levels is dependent on protein stabilization'
Concannon, CG;FitzGerald, U;Holmberg, CI;Szegezdi, E;Sistonen, L;Samali, A (2005) 'CD95-mediated alteration in Hsp70 levels is dependent on protein stabilization'. Cell Stress & Chaperones, 10 :59-65 [Details] |
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(2011) | 'Partial XBP1 Knockdown Does Not Affect Viability of Oligodendrocyte Precursor Cells Exposed to New Models of Hypoxia and Ischemia In Vitro'
Kraskiewicz, H;FitzGerald, U (2011) 'Partial XBP1 Knockdown Does Not Affect Viability of Oligodendrocyte Precursor Cells Exposed to New Models of Hypoxia and Ischemia In Vitro'. Journal Of Neuroscience Research, 89 :661-673 [DOI] [Details] |
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(2013) | 'Calreticulin and other components of endoplasmic reticulum stress in rat and human inflammatory demyelination'
Fhlathartaigh, MN;McMahon, J;Reynolds, R;Connolly, D;Higgins, E;Counihan, T;FitzGerald, U (2013) 'Calreticulin and other components of endoplasmic reticulum stress in rat and human inflammatory demyelination'. Acta Neuropathologica Communications, 1 [DOI] [Details] |
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(2016) | 'Significant glial alterations in response to iron loading in a novel organotypic hippocampal slice culture model'
Healy, S;McMahon, J;Owens, P;FitzGerald, U (2016) 'Significant glial alterations in response to iron loading in a novel organotypic hippocampal slice culture model'. Scientific Reports, 6 [DOI] [Details] |
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(2018) | 'UPR Induction Prevents Iron Accumulation and Oligodendrocyt Loss in ex vivo Cultured Hippocampal Slices'
Healy, S,McMahon, J,FitzGerald, U (2018) 'UPR Induction Prevents Iron Accumulation and Oligodendrocyt Loss in ex vivo Cultured Hippocampal Slices'. Frontiers In Neuroscience, 12 [DOI] [Details] |
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(2019) | 'Mitral cells and the glucagon-like peptide 1 receptor: The sweet smell of success?'
Bagnoli, E,FitzGerald, U (2019) 'Mitral cells and the glucagon-like peptide 1 receptor: The sweet smell of success?'. European Journal Of Neuroscience, 49 :422-439 [DOI] [Details] |
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(2018) | 'Threshold-based segmentation of fluorescent and chromogenic images of microglia, astrocytes and oligodendrocytes in FIJI'
Healy, S,McMahon, J,Owens, P,Dockery, P,FitzGerald, U (2018) 'Threshold-based segmentation of fluorescent and chromogenic images of microglia, astrocytes and oligodendrocytes in FIJI'. Journal Of Neuroscience Methods, 295 :87-103 [DOI] [Details] |
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(2018) | 'Ulk4 deficiency leads to hypomyelination in mice'
Liu, M,Xu, P,Guan, ZL,Qian, XH,Dockery, P,Fitzgerald, U,O'Brien, T,Shen, SB (2018) 'Ulk4 deficiency leads to hypomyelination in mice'. Glia, 66 :175-190 [DOI] [Details] |
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(2016) | 'Ulk4 Is Essential for Ciliogenesis and CSF Flow'
Liu, M,Guan, ZL,Shen, Q,Lalor, P,Fitzgerald, U,O'Brien, T,Dockery, P,Shen, SB (2016) 'Ulk4 Is Essential for Ciliogenesis and CSF Flow'. Journal Of Neuroscience, 36 :7589-7600 [DOI] [Details] |
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(2013) | 'An ex-vivo multiple sclerosis model of inflammatory demyelination using hyperbranched polymer'
Mathew, A;Pakan, JMP;Collin, EC;Wang, WX;McDermott, KW;Fitzgerald, U;Reynolds, R;Pandit, AS (2013) 'An ex-vivo multiple sclerosis model of inflammatory demyelination using hyperbranched polymer'. Biomaterials, 34 :5872-5882 [DOI] [Details] |
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(2015) | 'Differential activation of ER stress pathways in myelinating cerebellar tracts'
Naughton, MC,McMahon, JM,FitzGerald, U (2015) 'Differential activation of ER stress pathways in myelinating cerebellar tracts'. International Journal Of Developmental Neuroscience, 47 :347-360 [DOI] [Details] |
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(2012) | 'Increased expression of ER stress- and hypoxia-associated molecules in grey matter lesions in multiple sclerosis'
McMahon, J. M.,McQuaid, S.,Reynolds, R.,FitzGerald, U. F. (2012) 'Increased expression of ER stress- and hypoxia-associated molecules in grey matter lesions in multiple sclerosis'. Mult Scler, 18 (1010):1437-47 [Details] |
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(2011) | 'Expression profiles of endoplasmic reticulum stress-related molecules in demyelinating lesions and multiple sclerosis'
Cunnea, P,Mhaille, AN,McQuaid, S,Farrell, M,McMahon, J,FitzGerald, U (2011) 'Expression profiles of endoplasmic reticulum stress-related molecules in demyelinating lesions and multiple sclerosis'. Multiple Sclerosis Journal, 17 :808-818 [DOI] [Details] |
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(2010) | 'Methods for Monitoring Endoplasmic Reticulum Stress and the Unfolded Protein Response'
Samali, A., Fitzgerald, U., Deegan, S., & Gupta, S. (2010) 'Methods for Monitoring Endoplasmic Reticulum Stress and the Unfolded Protein Response'. International Journal Of Cell Biology, [ARAN Link] [Details] |
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(2010) | 'Gene expression analysis of the microvascular compartment in multiple sclerosis using laser microdissected blood vessels'
Cunnea, P,McMahon, J,O'Connell, E,Mashayekhi, K,Fitzgerald, U,McQuaid, S (2010) 'Gene expression analysis of the microvascular compartment in multiple sclerosis using laser microdissected blood vessels'. Acta Neuropathologica, 119 :601-615 [DOI] [Details] |
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(2009) | 'The effects of blood-brain barrier disruption on glial cell function in Multiple Sclerosis'
Stephen McQuaid, Paula Cunnea, Jill McMahon, Una FitzGerald (2009) 'The effects of blood-brain barrier disruption on glial cell function in Multiple Sclerosis'. Biochemical Society Transactions, [Details] |
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(2008) | 'Increased expression of endoplasmic reticulum stress-related signaling pathway molecules in multiple sclerosis lesions'
Mhaille, AN,McQuaid, S,Windebank, A,Cunnea, P,McMahon, J,Samali, A,FitzGerald, U (2008) 'Increased expression of endoplasmic reticulum stress-related signaling pathway molecules in multiple sclerosis lesions'. Journal Of Neuropathology And Experimental Neurology, 67 :200-211 [Details] |
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(2007) | 'Absence of aquaporin-4 expression in lesions of neuromyelitis optica but increased expression in multiple sclerosis lesions and normal-appearing white matter'
Sinclair, C,Kirk, J,Herron, B,Fitzgerald, U,McQuaid, S (2007) 'Absence of aquaporin-4 expression in lesions of neuromyelitis optica but increased expression in multiple sclerosis lesions and normal-appearing white matter'. Acta Neuropathologica, 113 :187-194 [DOI] [Details] |
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(2005) | 'Role of Mayven, a Kelch-related protein in oligodendrocyte process formation'
Williams, SK,Spence, HJ,Rodgers, RR,Ozanne, BW,Fitzgerald, U,Barnett, SC (2005) 'Role of Mayven, a Kelch-related protein in oligodendrocyte process formation'. Journal Of Neuroscience Research, 81 :622-631 [DOI] [Details] |
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(2003) | 'Caspase-12 and ER-stress-mediated apoptosis - The story so far'
Szegezdi, E,Fitzgerald, U,Samali, A,Diederich, M (2003) 'Caspase-12 and ER-stress-mediated apoptosis - The story so far'. Annals Of The New York Academy Of Sciences, 1010 :186-194 [DOI] [Details] |
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(2003) | 'In the cut and thrust of apoptosis, serine proteases come of age'
Stenson-Cox C, FitzGerald U, Samali A (2003) 'In the cut and thrust of apoptosis, serine proteases come of age'. Biochemical Pharmacology, 66 (8):1469-1474 [Details] |
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(2003) | 'Caspase-12 and ER-stress-mediated apoptosis: the story so far'
Szegezdi E, Fitzgerald U, Samali A (2003) 'Caspase-12 and ER-stress-mediated apoptosis: the story so far'. Annals of the New York Academy of Sciences, 1010 :186-194 [Details] |
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(2003) | 'Hypoxia and ischemia induce nuclear condensation and caspase activation in cardiomyocytes'
O'Mahoney ME, Logue S, Szegezdi E, Stenson-Cox C, Fitzgerald U, Samali A (2003) 'Hypoxia and ischemia induce nuclear condensation and caspase activation in cardiomyocytes'. Annals of the New York Academy of Sciences, 1010 :728-732 [Details] |
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(2003) | 'Hypoxia and ischemia induce nuclear condensation and caspase activation in cardiomyocytes'
O'Mahoney, M. E.,Logue, S.,Szegezdi, E.,Stenson-Cox, C.,Fitzgerald, U.,Samali, A. (2003) 'Hypoxia and ischemia induce nuclear condensation and caspase activation in cardiomyocytes'. Annals N.Y. Acad. Sci, 1010 :728-732 [Details] |
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(2003) | 'In the cut and thrust of apoptosis, serine proteases come of age'
Stenson-Cox, C.M., FitzGerald, U., Samali, A. (2003) 'In the cut and thrust of apoptosis, serine proteases come of age'. Biochem Biopharm, 66 :1469-1474 [Details] |
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(2000) | 'AP-1 activity during the growth, differentiation, and death of O-2A lineage cells'
FitzGerald, U., and Barnett, S.C. (2000) 'AP-1 activity during the growth, differentiation, and death of O-2A lineage cells'. Mol Cell Neurosci, 16 :453-469 [Details] |
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(2000) | 'Krp1, a novel kelch related protein that is involved in pseudopod elongation in transformed cells'
Spence, H.J., Johnston, I., Ewart, K., Buchanan, S.J., FitzGerald, U, Ozanne, B.W. (2000) 'Krp1, a novel kelch related protein that is involved in pseudopod elongation in transformed cells'. Oncogene, 19 :1266-1276 [Details] |
Book Chapters
Year | Publication | |
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(2006) | 'Molecular basis of inhibition of apoptosis by Heat shock proteins'
Gill C., Meyer M., Samali A. (2006) 'Molecular basis of inhibition of apoptosis by Heat shock proteins' In: Stress response: a molecular Biology approach. India: Research Signpost. [Details] |
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(2005) | 'Heat shock proteins in regulation of neural apoptosis'
FitzGerald U., Gorman A.M., Samali A. (2005) 'Heat shock proteins in regulation of neural apoptosis' In: Heat Shock Proteins in Neural Cells. USA: Landes Bioscience. [Details] |
Conference Publications
Year | Publication | |
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(2019) | BNA 2019 Festival of Neuroscience
Okolo, A; Shearer, J; Prendergast, J; Douglas, A; McMahon, J; Fitzgerald, U; Doyle, K (2019) CHANGE IN ATF6 AND CHOP EXPRESSION IN THE BRAIN, FOLLOWING ISCHEMIC STROKE AND REPERFUSION BNA 2019 Festival of Neuroscience Dublin, Ireland, , 14-APR-19 - 17-APR-19 [Details] |
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(2003) | BIOCHEMICAL PHARMACOLOGY
Stenson-Cox, C;FitzGerald, U;Samali, A (2003) In the cut and thrust of apoptosis, serine proteases come of age BIOCHEMICAL PHARMACOLOGY , pp.1469-1474 [DOI] [Details] |
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(2003) | APOPTOSIS: FROM SIGNALING PATHWAYS TO THERAPEUTIC TOOLS
O'Mahoney, ME;Logue, S;Szegezdi, E;Stenson-Cox, C;Fitzgerald, U;Samali, A (2003) Hypoxia and ischemia induce nuclear condensation and caspase activation in cardiomyocytes APOPTOSIS: FROM SIGNALING PATHWAYS TO THERAPEUTIC TOOLS , pp.728-732 [DOI] [Details] |
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(2003) | APOPTOSIS: FROM SIGNALING PATHWAYS TO THERAPEUTIC TOOLS
Szegezdi, E;Fitzgerald, U;Samali, A (2003) Caspase-12 and ER-stress-mediated apoptosis - The story so far APOPTOSIS: FROM SIGNALING PATHWAYS TO THERAPEUTIC TOOLS , pp.186-194 [DOI] [Details] |
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(2009) | BIOCHEMICAL SOCIETY TRANSACTIONS
McQuaid, S;Cunnea, P;McMahon, J;Fitzgerald, U (2009) The effects of blood-brain barrier disruption on glial cell function in multiple sclerosis BIOCHEMICAL SOCIETY TRANSACTIONS , pp.329-331 [DOI] [Details] |
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(2016) | Oligodendrocyte loss in hippocampal slice culture model of iron accumulation
Healy, S,McMahon, J,FitzGerald, U (2016) IRISH JOURNAL OF MEDICAL SCIENCE Oligodendrocyte loss in hippocampal slice culture model of iron accumulation , pp.179-180 [Details] |
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(2015) | Ferrocene perturbs iron metabolism in organotypic hippocampal slices
Healy, S,McMahon, J,FitzGerald, U (2015) IRISH JOURNAL OF MEDICAL SCIENCE Ferrocene perturbs iron metabolism in organotypic hippocampal slices , pp.12-13 [Details] |
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(2009) | The effects of blood-brain barrier disruption on glial cell function in multiple sclerosis
McQuaid, S,Cunnea, P,McMahon, J,Fitzgerald, U (2009) BIOCHEMICAL SOCIETY TRANSACTIONS The effects of blood-brain barrier disruption on glial cell function in multiple sclerosis , pp.329-331 [DOI] [Details] |
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(2003) | Hypoxia and ischemia induce nuclear condensation and caspase activation in cardiomyocytes
O'Mahoney, ME,Logue, S,Szegezdi, E,Stenson-Cox, C,Fitzgerald, U,Samali, A (2003) APOPTOSIS: FROM SIGNALING PATHWAYS TO THERAPEUTIC TOOLS Hypoxia and ischemia induce nuclear condensation and caspase activation in cardiomyocytes , pp.728-732 [DOI] [Details] |
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(2003) | In the cut and thrust of apoptosis, serine proteases come of age
Stenson-Cox, C,FitzGerald, U,Samali, A (2003) BIOCHEMICAL PHARMACOLOGY In the cut and thrust of apoptosis, serine proteases come of age , pp.1469-1474 [DOI] [Details] |
Conference Contributions
Year | Publication | |
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(2019) | European Meeting on Glial Cells in Health and Disease,
Bagnoli E, McMahon J, FitzGerald U (2019) Can we mimic prodromal Parkinsons disease in a dish? A story of the olfactory bulb and DOPAL. [Poster Presentation], European Meeting on Glial Cells in Health and Disease, Porto, Portugal , 10-JUL-19 - 13-JUL-19. [Details] |
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(2017) | European Meeting on Glial Cells in Health and Disease,
Healy S, McMahon J, Owens P, Dockery P, FitzGerald U (2017) Qualitative and quantitative evaluation of binarization algorithms for image analysis of glial cells 3D in ex vivo slice cultures. [Conference Organising Committee Chairperson], European Meeting on Glial Cells in Health and Disease, Edinburgh , 08-JUL-17 - 08-JUL-17. [Details] |
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(2017) | European Meeting on Glial Cells in Health and Disease,
Naughton M, McMahon J, FitzGerald U (2017) Distinct UPR profiles during maturation of glial and neuronal progenitors of the cerebellum. [Poster Presentation], European Meeting on Glial Cells in Health and Disease, Edinburgh , 09-JUL-17 - 09-JUL-17. [Details] |
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(2015) | Iron loading with ferrocene induces iron mismanagement in organotypic hippocampal slices,
Healy S, McMahon J, FitzGerald U (2015) GLIA Conference. [Poster Presentation], Iron loading with ferrocene induces iron mismanagement in organotypic hippocampal slices, Bilbao , 10-JUL-15. [Details] |
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(2014) | Endoplasmic reticulum stress-associated proteins in saliva: potential biomarkers for multiple sclerosis?,
McMahon, J,Higgins, E,Garvey, A,Counihan, T,Fitzgerald, U (2014) IRISH JOURNAL OF MEDICAL SCIENCE. [Conference Organising Committee Chairperson], Endoplasmic reticulum stress-associated proteins in saliva: potential biomarkers for multiple sclerosis?, Dublin , 10-MAY-14. [Details] |
Abstract
Year | Publication | |
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(2014) | Iron loading in brain slices: development of a novel in vitro platform to assess the impact of an iron-loaded environment in multiple sclerosis (MS).
Healy, S,Naughton, M,McMahon, J,FitzGerald, U (2014) Iron loading in brain slices: development of a novel in vitro platform to assess the impact of an iron-loaded environment in multiple sclerosis (MS). Abstract [Details] |
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(2014) | Increased endoplasmic reticulum stress signalling in rat white matter development.
Naughton, M,McMahon, J,Fitzgerald, U (2014) Increased endoplasmic reticulum stress signalling in rat white matter development. Abstract [Details] |
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(2013) | Is B cell immunoglobulin (BiP) a useful biomarker for Multiple Sclerosis?.
Higgins, E,McMahon, J,Counihan, T,FitzGerald, U (2013) Is B cell immunoglobulin (BiP) a useful biomarker for Multiple Sclerosis?. Abstract [Details] |
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(2011) | ENDOPLASMIC RETICULUM STRESS AS A COMPONENT OF DEMYELINATION IN A CORTICAL EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS MODEL OF MULTIPLE SCLEROSIS.
Ni Fhlathartaigh, M,McMahon, J,Reynolds, R,FitzGerald, U (2011) ENDOPLASMIC RETICULUM STRESS AS A COMPONENT OF DEMYELINATION IN A CORTICAL EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS MODEL OF MULTIPLE SCLEROSIS. Abstract [Details] |
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(2011) | IS ER-STRESS AND/OR HYPOXIA INVOLVED IN THE PATHOLOGY OF GREY MATTER LESION DEVELOPMENT IN MULTIPLE SCLEROSIS?.
McMahon, J,McQuaid, S,Farrell, M,FitzGerald, U (2011) IS ER-STRESS AND/OR HYPOXIA INVOLVED IN THE PATHOLOGY OF GREY MATTER LESION DEVELOPMENT IN MULTIPLE SCLEROSIS?. Abstract [Details] |
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(2011) | CHARACTERIZATION OF MARKERS OF ENDOPLASMIC RETICULUM STRESS IN AN EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS MODEL OF MULTIPLE SCLEROSIS.
Fhlathartaigh, MN,McMahon, J,Reynolds, R,FitzGerald, U (2011) CHARACTERIZATION OF MARKERS OF ENDOPLASMIC RETICULUM STRESS IN AN EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS MODEL OF MULTIPLE SCLEROSIS. Abstract [Details] |
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(2011) | EXPRESSION OF ER STRESS- AND HYPOXIA-ASSOCIATED MOLECULES IN GREY MATTER LESIONS IN MULTIPLE SCLEROSIS.
McMahon, J,McQuaid, S,Reynolds, R,Fitzgerald, U (2011) EXPRESSION OF ER STRESS- AND HYPOXIA-ASSOCIATED MOLECULES IN GREY MATTER LESIONS IN MULTIPLE SCLEROSIS. Abstract [Details] |
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(2009) | DETECTION OF MARKERS OF ENDOPLASMIC RETICULUM STRESS IN INFARCTED HUMAN BRAIN AND IN NEWLY-DEVELOPED IN VITRO MODELS OF OLIGODENDROCYTE ISCHAEMIA.
Kraskiewicz, H,Ni Mhaille, A,Roemer, S,Lucchinetti, C,Fitzgerald, U (2009) DETECTION OF MARKERS OF ENDOPLASMIC RETICULUM STRESS IN INFARCTED HUMAN BRAIN AND IN NEWLY-DEVELOPED IN VITRO MODELS OF OLIGODENDROCYTE ISCHAEMIA. Abstract [Details] |
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(2009) | WHAT IS ENDOPLASMIC RETICULUM STRESS DOING DURING MULTIPLE SCLEROSIS PROGRESSION?.
Mcmahon, J,Mhaille, AN,Mcquaid, S,Farrell, M,Cunnea, P,Dolphin, C,Samali, A,Fitzgerald, U (2009) WHAT IS ENDOPLASMIC RETICULUM STRESS DOING DURING MULTIPLE SCLEROSIS PROGRESSION?. Abstract [Details] |
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(2007) | Endoplasmic reticulum stress in multiple sclerosis.
Mhaille, AN,McQuaid, S,Windebank, A,Cunnea, P,McMahon, J,Samali, A,FitzGerald, U (2007) Endoplasmic reticulum stress in multiple sclerosis. Abstract [Details] |
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(2005) | Staurosporine-induced cell death requires caspase and non-caspase dependant proteolytic mechanisms in a cell specific manner.
Stenson-Cox, CM,Holohan, C,Fitzgerald, U,Samali, A (2005) Staurosporine-induced cell death requires caspase and non-caspase dependant proteolytic mechanisms in a cell specific manner. Abstract [Details] |
ANET/COS
Year | Publication | |
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(2018) | Qualitative and quantitative evaluation of binarization algorithms for image analysis of glial cells 3D in ex vivo slice cultures.
Healy, S,McMahon, J,Owens, P,Dockery, P,FitzGerald, U (2018) Qualitative and quantitative evaluation of binarization algorithms for image analysis of glial cells 3D in ex vivo slice cultures. ANET/COS [Details] |
Conference Paper
Year | Publication | |
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(2015) | Endoplasmic reticulum stress: jack of all trades in multiple sclerosis.
McMahon, J,Naughton, M,Healy, S,FitzGerald, U (2015) Endoplasmic reticulum stress: jack of all trades in multiple sclerosis. Conference Paper [Details] |
Editorial
Year | Publication | |
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(2019) | Can we mimic prodromal Parkinson's disease in a dish? A story of the olfactory bulb and DOPAL.
Bagnoli, E,MacMahon, J,FitzGerald, U (2019) Can we mimic prodromal Parkinson's disease in a dish? A story of the olfactory bulb and DOPAL. Editorial [Details] |
Meeting
Year | Publication | |
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(2013) | Profile of Calreticulin and Other Endoplasmic Reticulum Stress Molecules in an Experimental Autoimmune Encephalomyelitis Animal Model of Multiple Sclerosis.
Fhlathartaigh, MN,McMahon, J,Reynolds, R,FitzGerald, U (2013) Profile of Calreticulin and Other Endoplasmic Reticulum Stress Molecules in an Experimental Autoimmune Encephalomyelitis Animal Model of Multiple Sclerosis. Meeting [Details] |
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(2013) | Pathological expression of calreticulin and other endoplasmic reticulum stress molecules in an experimental autoimmune encephalomyelitis animal model of multiple sclerosis.
Fhlathartaigh, MN,McMahon, J,Reynolds, R,FitzGerald, U (2013) Pathological expression of calreticulin and other endoplasmic reticulum stress molecules in an experimental autoimmune encephalomyelitis animal model of multiple sclerosis. Meeting [Details] |
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(2013) | CALRETICULIN: A NEW TWIST IN THE ENDOPLASMIC RETICULUM AND MULTIPLE SCLEROSIS TALE.
FitzGerald, U,McMahon, J,Ni Fhlathartaigh, M,Cunnea, P,Ni Mhaille, A,McQuaid, S,Farrel, M,Reynolds, R,Connolly, D (2013) CALRETICULIN: A NEW TWIST IN THE ENDOPLASMIC RETICULUM AND MULTIPLE SCLEROSIS TALE. Meeting [Details] |
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(2013) | EXPRESSION OF CALRETICULIN AND OTHER ENDOPLASMIC RETICULUM STRESS MOLECULES IN A RAT MODEL OF INFLAMMATORY DEMYELINATION.
FitzGerald, U,Fhlathartaigh, MN,McMahon, J,Reynolds, R (2013) EXPRESSION OF CALRETICULIN AND OTHER ENDOPLASMIC RETICULUM STRESS MOLECULES IN A RAT MODEL OF INFLAMMATORY DEMYELINATION. Meeting [Details] |
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(2011) | DETECTION OF MARKERS OF ENDOPLASMIC RETICULUM STRESS IN A RAT FOCAL CEREBRAL ISCHAEMIA MODEL.
Kraskiewicz, H,McMahon, J,McCabe, C,Macrae, M,FitzGerald, U (2011) DETECTION OF MARKERS OF ENDOPLASMIC RETICULUM STRESS IN A RAT FOCAL CEREBRAL ISCHAEMIA MODEL. Meeting [Details] |
Reviews
Year | Publication | |
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(2018) | Seeing the wood for the trees: towards improved quantification of glial cells in central nervous system tissue.
Healy, S;McMahon, J;FitzGerald, U (2018) Seeing the wood for the trees: towards improved quantification of glial cells in central nervous system tissue. MUMBAI: Reviews [DOI] [Details] |
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(2018) | Interplay of Inflammatory Mediators with Epigenetics and Cartilage Modifications in Osteoarthritis.
Raman, S;FitzGerald, U;Murphy, JM (2018) Interplay of Inflammatory Mediators with Epigenetics and Cartilage Modifications in Osteoarthritis. LAUSANNE: Reviews [DOI] [Details] |
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(2018) | A lifetime of stress: ATF6 in development and homeostasis.
Hillary, RF;FitzGerald, U (2018) A lifetime of stress: ATF6 in development and homeostasis. LONDON: Reviews [DOI] [Details] |
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(2018) | MARCKS and MARCKS-like proteins in development and regeneration.
El Amri, M;Fitzgerald, U;Schlosser, G (2018) MARCKS and MARCKS-like proteins in development and regeneration. LONDON: Reviews [DOI] [Details] |
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(2017) | Modelling iron mismanagement in neurodegenerative disease in vitro: paradigms, pitfalls, possibilities & practical considerations.
Healy, S;McMahon, JM;FitzGerald, U (2017) Modelling iron mismanagement in neurodegenerative disease in vitro: paradigms, pitfalls, possibilities & practical considerations. OXFORD: Reviews [DOI] [Details] |
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(2016) | In vitro and ex vivo models of multiple sclerosis.
Madill M;Fitzgerald D;O'Connell KE;Dev KK;Shen S;FitzGerald U; (2016) In vitro and ex vivo models of multiple sclerosis. Reviews [DOI] [Details] |
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(2012) | InterfERing with endoplasmic reticulum stress.
Kraskiewicz, H,FitzGerald, U (2012) InterfERing with endoplasmic reticulum stress. Reviews [DOI] [Details] |
Professional Associations
Association | Function | From / To | |
---|---|---|---|
Neuroscience Ireland | Member | 01-AUG-06 / | |
Biochemistry Society | Member | 01-OCT-03 / | |
Irish Institute of Clinical Science | Member of Board of DIrectors, representing neuroscientists | 20-DEC-14 / | |
MS Ireland | Member of Expert Panel | 01-JAN-16 / |
Committees
Committee | Function | From / To | |
---|---|---|---|
Neuroscience Ireland Conference Organising Committee | Organisation of Neuroscience Ireland Conference at NUIG, 2017 | 03-OCT-16 / 25-AUG-17 | |
MS Ireland Advisory Committee | Member of Board of Advisors, representing neuroscientists | 01-JAN-16 / | |
College of Science Graduate Studies Committee | Representing postgraduate taught programmes in the College of Sience | 02-NOV-15 / | |
Board of Directors of the Irish Institute of Clinical Neuroscience | Representing Neuroscientists | 06-DEC-14 / 10-DEC-16 | |
School of Natural Science Executive Committee | Representing postgraduate taught programmes | 24-SEP-14 / |
Employment
Employer | Position | From / To | |
---|---|---|---|
University of Glasgow | Postdoctoral Researcher | 01-OCT-97 / 31-JUL-02 | |
NUIG | Postdoctoral Researcher (senior scientist) | 01-OCT-03 / 31-JAN-06 |
Education
Year | Institution | Qualification | Subject | |
---|---|---|---|---|
1993 | University of Strathclyde | PhD | Molecular Biology | |
1985 | UCG (now NUI Galway) | MASTERS OF SCIENCE | Biotechnology | |
1983 | UCG (now NUI Galway) | BACHELOR OF ENGINEERING | Industrial Engineering | |
2005 | NUI Galway | Diploma | Gaeilge |
Community Engagement
Title | Type | From / To | |
---|---|---|---|
Outreach | Science Festival | 23-NOV-14 / | |
Outreach | Brain Awareness Week | 07-MAR-12 / 08-MAR-12 |
Reviews
Journal | Role | |
---|---|---|
Journal Of Neuropathology And Experimental Neurology | Editor | |
Febs Letters | Reviewer | |
Neural Regeneration Research | Reviewer | |
Multiple Sclerosis Journal | Reviewer | |
Journal Of Neuroscience Research | Reviewer | |
Brain Research | Reviewer | |
Brain Research | Reviewer |
Teaching Interests
Current Postgraduate Students (Taught)
Name | Degree | Primary Supervisor | |
---|---|---|---|
Lianne Carey | Msc | Y | |
John Exton | Msc | Y | |
Thomas Tuohy | Msc | Y | |
Aoife McConnan | Msc | ||
Deirdre Ryan | Msc | Y | |
Jacqueline Roche | Msc | Y |
Recent Postgraduate Students
Graduation | Name | Degree | Primary Supervisor | |
---|---|---|---|---|
2012 | Honorata Kraskiewicz | PhD | Y | |
2008 | Aoife Ni Mhaille | PhD | Y | |
2017 | Sinead Healy | PhD | Y | |
2013 | Mary Ni Fhlathartaigh | PhD | Y |
Current Postgraduate Students (Research)
Student | Degree Type | Type | |
---|---|---|---|
Sravanthi Bandla | Doctorate - Structured PhD (Science) | Supervisor |
Modules Taught
Term/Year | Module Title | Module Code | Subject / Desc | |
---|---|---|---|---|
Distance/blended learning module for MSc students | Molecular and Cellular Biology | BES514 | Cell structure and function; How cells obtain energy; Reproduction at the cellular level; Molecular Biology; Biotechnoloy; DNA recombination. | |
Sem 1, 2007-present (alternate years); MSc | Molecular and Regenerative Medicine | BES510 | Module Director; Deliver content relating to drug discovery and Neurodegenerative disorders; Deliver approx one quarter to one third of module content. | |
Sem2, MSc | Specialised Studies | PH5101 | Workshop on Scientific Writing | |
Sem1 - MSc | Specialised Studies | IE585 | Workshop on Scientific Writing | |
Sem2 2005-16, delivered to FT Biomed MSc students | Molecular Medicine | BES554 | Quarter of module - on neurodegenerative disorders | |
Semester 2, delivered to FT Biomed MSc students | Scientific Writing | BES519 | Publication metrics (journal, author, country); Publication ethics; Grammar; Preparation of a mini-review. | |
From 2005-2015 (Full-time Biomed MSc students) | Principles of Cell and Molecular Biology | BES503 | As for BES514 |
Internal Collaborators
Name | Description of Collaboration | |
---|---|---|
Professor Abhay Pandit | ||
Dr. Manus Biggs | ||
Professor Sanbing Shen | ||
Professor Heinz-Peter Nasheuer | ||
Dr. Karen Doyle | ||
Professor Peter Dockery |
External Collaborators
Name | Organisation / Institute | Country | Description of Collaboration | |
---|---|---|---|---|
Professor Richard Reynolds | Imperial College, London | ENGLAND | ||
Dr. Denise Fitzgerald | Queen's University, Belfast | UNITED KINGDOM | ||
Professor Claude Bernard | Monash University, Melbourne | AUSTRALIA | ||
Professor Christopher Linington | Glasgow University | SCOTLAND |