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Medicine

Dr. Leo Quinlan


Contact Details

Lecturer Above The Bar
Dept. of Physiology
Quadrangle Building
NUI Galway

T: Ext. 3710
E: leo.quinlan@nuigalway.ie
 
researcher

Biography

Leo R. Quinlan received his BSc degree in Biochemistry in 1994 and was awarded his Ph.D. degree in stem cell biology in 1997 from the National University of Ireland Galway. From there he worked as a research fellow at the cellular physiology research unit University College Cork. In 1999 he was appointed as Lecturer in Physiology School of Medicine, National University of Ireland Galway. His current research interests include medical device development, usability, neural modulation, electrophysiology and ion channel function in neural and non neural systems. Dr. Quinlan is a member of a number of biomedical engineering and physiological related societies and he is a referee for a number biomedical, cellular and molecular based journals.

Research Interests

  • Medical Devices
  • Usability and Human Factors
  • Electrophysiology
    • Neuromuscular Electrical stimulation
    • Neuromodulation
    • Ion channel physiology
    • Neuronal noise
  • Stem cells and pluirpotency
  • Cell signalling
  • Biomaterials 
  • Human Movement Sensing
  • Connected Health Systems

Peer Reviewed Journals

  Year Publication
(2016) 'Analysis of swimming performance: perceptions and practices of US-based swimming coaches'
Mooney, R,Corley, G,Godfrey, A,Osborough, C,Newell, J,Quinlan, LR,OLaighin, G (2016) 'Analysis of swimming performance: perceptions and practices of US-based swimming coaches'. Journal Of Sports Sciences, 34 :997-1005 [DOI] [Details]
(2016) 'Dopaminergic-induced dyskinesia assessment based on a single belt-worn accelerometer'
Perez-Lopez, C,Sama, A,Rodriguez-Martin, D,Moreno-Arostegui, JM,Cabestany, J,Bayes, A,Mestre, B,Alcaine, S,Quispe, P,Laighin, GO,Sweeney, D,Quinlan, LR,Counihan, TJ,Browne, P,Annicchiarico, R,Costa, A,Lewy, H,Rodriguez-Molinero, A (2016) 'Dopaminergic-induced dyskinesia assessment based on a single belt-worn accelerometer'. Artificial Intelligence In Medicine, 67 :47-56 [DOI] [Details]
(2016) 'The Use of Intermittent Pneumatic Compression in Orthopedic and Neurosurgical Postoperative Patients: A Systematic Review and Meta-analysis'
O'Connell S, Bashar K, Broderick BJ, Sheehan J, Quondamatteo F, Walsh SR, ÓLaighin G, Quinlan LR. (2016) 'The Use of Intermittent Pneumatic Compression in Orthopedic and Neurosurgical Postoperative Patients: A Systematic Review and Meta-analysis'. Annals Of Surgery, [Details]
(2016) 'Detecting freezing of gait with a tri-axial accelerometer in Parkinson's disease patients'
Ahlrichs, C,Sama, A,Lawo, M,Cabestany, J,Rodriguez-Martin, D,Perez-Lopez, C,Sweeney, D,Quinlan, LR,Laighin, GO,Counihan, T,Browne, P,Hadas, L,Vainstein, G,Costa, A,Annicchiarico, R,Alcaine, S,Mestre, B,Quispe, P,Bayes, A,Rodriguez-Molinero, A (2016) 'Detecting freezing of gait with a tri-axial accelerometer in Parkinson's disease patients'. Medical & Biological Engineering & Computing, 54 :223-233 [DOI] [Details]
(2015) 'Hypoxia limits mouse follicle growth in vitro'
Connolly JM, Kane MT, Quinlan LR, Dockery P, Hynes AC (2015) 'Hypoxia limits mouse follicle growth in vitro'. Reprod Fertil Dev, [DOI] [Details]
(2015) 'Application of Video-Based Methods for Competitive Swimming Analysis: A Systematic Review'
Robert Mooney · Gavin Corley · Alan Godfrey · Conor Osborough · Leo Quinlan · Gearoid Olaighin (2015) 'Application of Video-Based Methods for Competitive Swimming Analysis: A Systematic Review'. Sports and Exercise Medicine, 1 (5):133-150 [ARAN Link] [Details]
(2015) 'Detecting freezing of gait with a tri-axial accelerometer in Parkinson’s disease patients'
Claas Ahlrichs · Albert Samà · Michael Lawo · Joan Cabestany · Daniel Rodríguez-Martín · Carlos Pérez-López · Dean Sweeney · Leo R. Quinlan · Gearòid Ò Laighin · Timothy Counihan · Patrick Browne · Lewy Hadas · Gabriel Vainstein · Alberto Costa · Roberta Annicchiarico · Sheila Alcaine · Berta Mestre · Paola Quispe · Àngels Bayes · Alejandro Rodríguez-Molinero (2015) 'Detecting freezing of gait with a tri-axial accelerometer in Parkinson’s disease patients'. Medical & Biological Engineering & Computing, [Details]
(2014) 'A new paradigm of electrical stimulation to enhance sensory neural function'
Breen, PP,OLaighin, G,McIntosh, C,Dinneen, SF,Quinlan, LR,Serrador, JM (2014) 'A new paradigm of electrical stimulation to enhance sensory neural function'. Medical Engineering & Physics, 36 :1088-1091 [DOI] [Details]
(2014) 'Comparative lower limb hemodynamics using neuromuscular electrical stimulation (NMES) versus intermittent pneumatic compression (IPC)'
Broderick, BJ,O'Connell, S,Moloney, S,O'Halloran, K,Sheehan, J,Quondamatteo, F,Quinlan, LR,OLaighin, G (2014) 'Comparative lower limb hemodynamics using neuromuscular electrical stimulation (NMES) versus intermittent pneumatic compression (IPC)'. Physiological Measurement, 35 :1849-1859 [DOI] [Details]
(2015) 'Hyaluronic acid decreases IL-6 and IL-8 secretion and permeability in an inflammatory model of interstitial cystitis'
Rooney, P,Srivastava, A,Watson, L,Quinlan, LR,Pandit, A (2015) 'Hyaluronic acid decreases IL-6 and IL-8 secretion and permeability in an inflammatory model of interstitial cystitis'. Acta Biomaterialia, 19 :66-75 [DOI] [Details]
(2014) 'A new paradigm of electrical stimulation to enhance sensory neural function'
PP Breen, G ÓLaighin, C McIntosh, SF Dinneen, LR Quinlan, JM Serrador. (2014) 'A new paradigm of electrical stimulation to enhance sensory neural function'. Medical Engineering & Physics, 36 (8):1088-1091 [Details]
(2014) 'Comparative lower limb hemodynamics using neuromuscular electrical stimulation (NMES) versus intermittent pneumatic compression (IPC)'
Broderick, B. J. O'Connell, S. Moloney, S. O'Halloran, K. Sheehan, J. Quondamatteo, F. Quinlan, L. R. O. Laighin G (2014) 'Comparative lower limb hemodynamics using neuromuscular electrical stimulation (NMES) versus intermittent pneumatic compression (IPC)'. Physiological Measurements, 35 (9):1849-1859 [Details]
(2014) 'The past, present and future in scaffold-based tendon treatments'
Lomas, A. J. Ryan, C. N. Sorushanova, A. Shologu, N. Sideri, A. I. Tsioli, V. Fthenakis, G. C. Tzora, A. Skoufos, I. Quinlan, L. R. O'Laighin, G. Mullen, A. M. Kelly, J. L. Kearns, S. Biggs, M. Pandit, A. Zeugolis, D. I. (2014) 'The past, present and future in scaffold-based tendon treatments'. Advanced Drug Delivery Reviews, [Details]
(2014) 'Human Centred Design Considerations for Connected Health Devices for the Older Adult'
Richard P. Harte, Liam G. Glynn, Barry J. Broderick, Alejandro Rodriguez-Molinero, Paul M. A. Baker, Bernadette McGuiness, Leonard O’Sullivan, Marta Diaz, Leo R. Quinlan and Gearóid ÓLaighin (2014) 'Human Centred Design Considerations for Connected Health Devices for the Older Adult'. Journal of Personalized Medicine, 4 (2):245-281 [Details]
(2013) 'Concanavalin A-induced hepatitis: Gut derived LPS, intestinal permeability and TLR4'
Mallard BL, Mabuchi A, Akashi-Takamura S, Harper J, Quinlan LR, Wheatley AM (2013) 'Concanavalin A-induced hepatitis: Gut derived LPS, intestinal permeability and TLR4'. Hepatology, 58 (S1):966A-966A [Details]
(2012) 'Small conductance potassium channels drive ATP-activated chloride secretion in the oviduct'
Keating, N,Quinlan, LR (2012) 'Small conductance potassium channels drive ATP-activated chloride secretion in the oviduct'. American Journal Of Physiology-Cell Physiology, 302 :100-109 [DOI] [Details]
(2008) 'Effect of basolateral adenosine triphosphate on chloride secretion by bovine oviductal epithelium'
Keating, N,Quinlan, LR (2008) 'Effect of basolateral adenosine triphosphate on chloride secretion by bovine oviductal epithelium'. Biology Of Reproduction, 78 :1119-1126 [DOI] [Details]
(2007) 'Self-renewal and differentiation of mouse embryonic stem cells as measured by Oct4 expression: the role of the cAMP/PKA pathway'
Faherty, S,Fitzgerald, A,Keohan, M,Quinlan, LR (2007) 'Self-renewal and differentiation of mouse embryonic stem cells as measured by Oct4 expression: the role of the cAMP/PKA pathway'. In Vitro Cellular & Developmental Biology-Animal, 43 :37-47 [DOI] [Details]
(2005) 'Self-renewal and differentiation of mouse embryonic stem cells as measured by Oct4 gene expression: Effects of LIF, serum-free medium, retinoic acid, and dbcAMP'
Faherty, S,Kane, MT,Quinlan, LR (2005) 'Self-renewal and differentiation of mouse embryonic stem cells as measured by Oct4 gene expression: Effects of LIF, serum-free medium, retinoic acid, and dbcAMP'. In Vitro Cellular & Developmental Biology-Animal, 41 :356-363 [Details]
(2005) 'Self-renewal and differentiation of mouse embryonic stem cells as measured by Oct 4 gene expression: effects of lif, serum-free medium, retinoic acid, and dbcAMP'
Faherty, S., Kane, MT. and Quinlan LR (2005) 'Self-renewal and differentiation of mouse embryonic stem cells as measured by Oct 4 gene expression: effects of lif, serum-free medium, retinoic acid, and dbcAMP'. In Vitro Cellular & Developmental Biology-Animal, 41 (10):356-363 [DOI] [Details]
(2003) 'Phospholipase C and protein kinase C involvement in mouse embryonic stem-cell proliferation and apoptosis'
Quinlan, LR,Faherty, S,Kane, MT (2003) 'Phospholipase C and protein kinase C involvement in mouse embryonic stem-cell proliferation and apoptosis'. Reproduction, 126 :121-131 [Details]
(2001) 'Nature of glycosylphosphatidylinositols produced by mouse embryonic stem cells'
Quinlan, LR,Kane, MT (2001) 'Nature of glycosylphosphatidylinositols produced by mouse embryonic stem cells'. Reproduction, 122 :785-791 [Details]
(2000) 'Calcium confusion--is the variability in calcium response by Sertoli cells to specific hormones meaningful or simply redundant'
Rommerts FF, Lyng FM, von Ledebur E, Quinlan LR, Jones GR, Warchol JB, Stefanini M, Ravindranath N, Joffre M. (2000) 'Calcium confusion--is the variability in calcium response by Sertoli cells to specific hormones meaningful or simply redundant'. Journal Of Endocrinology, 167 (1):1-5 [Details]

Book Chapters

  Year Publication
(2011) 'Signaling Pathways in Mouse Embryo Stem Cell Self-Renewal'
Quinlan LR (2011) 'Signaling Pathways in Mouse Embryo Stem Cell Self-Renewal' In: Embryonic Stem Cells - Basic Biology to Bioengineering. Croatia: In Tech. [ARAN Link] [Details]
(2006) 'Phosphoinositides, inositol phosphates, and phospholipase C in embryonic stem cells'
Quinlan LR (2006) 'Phosphoinositides, inositol phosphates, and phospholipase C in embryonic stem cells' In: Methods in Molecular Biology - Embryonic Stem Cell Protocols. Totowa, NJ: Humana Press Inc. [DOI] [Details]

Conference Publications

  Year Publication
(2015) Smartphone App Design for the Wireless Control of a Neuromuscular Electrical Stimulator device with Integrated Randomization Allocation Process for RCT Applications
Sweeney, D,Quinlan, LR,OLaighin, G, (2015) 2015 37TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC) Smartphone App Design for the Wireless Control of a Neuromuscular Electrical Stimulator device with Integrated Randomization Allocation Process for RCT Applications , pp.4574-4577 [Details]
(2013) Digestive Diseases Week
Mallard, BL; Quinlan LR; Mabuchi, A; Wheatley, AM (2013) Concanavalin A-Induced Hepatitis in Mice is Prevented by Depletion of Gut Bacteria Using Antibiotics Digestive Diseases Week Orlando, Florida, USA, , 18-MAY-13 - 21-MAY-13 [Details]
(2013) Journal of Hepatology
BL Mallard, LR Quinlan, A Mabuchi, AM Wheatley (2013) DEPLETION OF GUT BACTERIA WITH ANTIBIOTICS PREVENTS CONCANAVALIN (Con) A INDUCED HEPATITIS IN MICE Journal of Hepatology [Details]
(2012) RAMI
O’Brien, C; Hutch, R; Callnan, D; McKeever, D; McDonnell, K; Wheatley, AM; Quinlan LR (2012) MODULATION OF GUT PERMEABILITY BY THE LECTIN CONCANAVALIN A AND LIPOPOLYSACCHARIDE : POTENTIAL NOVEL MECHANISM UNDERLYING INFLAMMATORY BOWEL DISEASE RAMI [Details]
(2012) RAMI
Cahill, N; Prendergast, T; McDonald, N; Mulleady, C; Quinlan, LR (2012) PURINERGIC MODULATION OF SPONTANEOUS RAT MYOMETRIAL CONTRACTILITY IN VITRO RAMI [Details]
(2012) International MSc Conference Galway
Burke, R; Miniter, A; Quinlan, LR (2012) hMSCs promote wound repair in T84 colon epithelial monolayers International MSc Conference Galway [Details]
(2012) FASEB JOURNAL
Breen, P; Serrador, J; O'Laighin, G; McIntosh, C; O'Tuathail, C; Quinlan, LR; Dinneen, SF; (2012) Peripheral Sensory Function Enhanced Using Stochastic Noise Stimulation FASEB JOURNAL [Details]

Published Reports

  Year Publication
(2013) Concanavalin A-induced hepatitis in mice is prevented by depletion of gut bacteria using antibiotics.
Mallard B, Quinlan LR, Mabuchi A, Wheatley AM (2013) Concanavalin A-induced hepatitis in mice is prevented by depletion of gut bacteria using antibiotics. Gastroenterology 144 (Supplement 1), S939, American Gastoenterological Society. [Details]

Abstract

  Year Publication
(2016) Enhancing Lower Limb Venous Haemodynamics Using Neuromuscular Electrical Stimulation (NMES).
O'Connell, S,Coneys, A,Gallagher, R,Quondamatteo, F,Broderick, BJ,Quinlan, LR,Laighin, GO (2016) Enhancing Lower Limb Venous Haemodynamics Using Neuromuscular Electrical Stimulation (NMES). Abstract [Details]
(2012) Peripheral Sensory Function Enhanced Using Stochastic Noise Stimulation.
Serrador, J,O'Laighin, G,McIntosh, C,O'Tuathail, C,Quinlan, LR,Dinneen, SF,Breen, P (2012) Peripheral Sensory Function Enhanced Using Stochastic Noise Stimulation. Abstract [Details]
(2011) PERIPHERAL SENSORY FUNCTION ENHANCED IN YOUNGER AND OLDER ADULTS USING A NOVEL ELECTRICAL STIMULATION BASED TECHNIQUE.
Breen, PP,Olaighin, G,McIntosh, C,O'Tuathail, C,Quinlan, LR,Dinneen, SF,Serrador, JM (2011) PERIPHERAL SENSORY FUNCTION ENHANCED IN YOUNGER AND OLDER ADULTS USING A NOVEL ELECTRICAL STIMULATION BASED TECHNIQUE. Abstract [Details]

Reviews

  Year Publication
(2016) Inertial Sensor Technology for Elite Swimming Performance Analysis: A Systematic Review.
Mooney, R,Corley, G,Godfrey, A,Quinlan, LR,OLaighin, G (2016) Inertial Sensor Technology for Elite Swimming Performance Analysis: A Systematic Review. Reviews [DOI] [Details]
(2015) The past, present and future in scaffold-based tendon treatments.
Lomas, AJ,Ryan, CNM,Sorushanova, A,Shologu, N,Sideri, AI,Tsioli, V,Fthenakis, GC,Tzora, A,Skoufos, I,Quinlan, LR,O'Laighin, G,Mullen, AM,Kelly, JL,Kearns, S,Biggs, M,Pandit, A,Zeugolis, DI (2015) The past, present and future in scaffold-based tendon treatments. Reviews [DOI] [Details]

Current Postgraduate Students (Research)

  Student Degree Type Type
Silvia Rosati Doctorate - Structured Ph.D (Medicine) Co-supervisor (1)
Sahar Avazzadeh Doctorate - Structured Ph.D (Medicine) Co-supervisor (1)
Kevin Cradock Doctorate - Structured Ph.D (Medicine) Supervisor
Dean Sweeney Doctorate - Structured Ph.D (Engineering) Co-supervisor (1)
Sandra O Connell Doctorate - Structured Ph.D (Medicine) Supervisor
Kevin O Halloran Doctorate - Structured PhD (Science) Supervisor
Richard Harte Doctorate - Structured Ph.D (Engineering) Co-supervisor (1)
Robert Mooney Doctorate - Structured Ph.D (Engineering) Co-supervisor (1)