Wednesday, 24 August 2016

CÚRAMs First Co-Funded Clinical Trial Successfully Completed with Arch Therapeutics

Arch Therapeutics, Inc. in collaboration with CÚRAM, Science Foundation Ireland Centre for Research in Medical Devices and the Clinical Research Facility at NUI Galway have successfully met the objectives of a recently completed single-center, randomized, single-blind prospective clinical study of the AC5 Topical Hemostatic DeviceTM in skin lesion patients with bleeding wounds. This was the first study assessing the safety and performance of AC5 in humans and was conducted at University College Hospital, Galway, Ireland. The objectives of the study were to evaluate the safety and performance of AC5 in patients scheduled to undergo excision of skin lesions on their trunk or upper limbs. The primary endpoint was safety throughout the surgical procedure and until the end of a 30-day follow-up period post procedure. Safety of the clinical investigation device was determined by monitoring for treatment related adverse events. The primary objective was met, as the safety outcomes of both the AC5 treatment group and the control group were similar. No serious adverse events were reported. A secondary endpoint was performance as assessed by time to hemostasis. The median time to hemostasis of wounds in the AC5 treatment group was 41% faster than for those in the control group. This result was statistically significant (p<0.001, Wilcoxon signed rank test). An additional secondary endpoint of healing of treated wounds was assessed as measured by the ASEPSIS wound score at Days 7 and 30. There was no evidence, at either follow-up day, of an adverse effect of AC5 treatment on the wound ASEPSIS score. The ASEPSIS score did not appear to be compromised, as the majority of patients had an ASEPSIS score of 0 in both wounds at Days 7 and 30. All AC5-treated wounds healed satisfactorily as per wound healing scoring criteria. Terrence W. Norchi, MD, President and CEO of Arch Therapeutics, said, "These top-line data support that AC5 was safe and performed as expected in the patients enrolled in this study. These successful results mark a significant milestone in the development of AC5 and we are grateful to the support we have received from our colleagues at CÚRAM and CRFG, as well as others involved in the process. We look forward to further advancing our self-assembling peptide technology platform for this and other applications." The clinical study enrolled 46 patients, including 10 who were taking antiplatelet monotherapy. Each patient had bleeding wounds created as a result of the excision of at least two skin lesions under local anesthetic in the same setting. On a randomized basis, one lesion received AC5 and the other(s) received a control treatment consisting of standard therapy plus a sham. Each subject was followed-up for safety assessment both on Day 7 and again on Day 30, which marked the end of the subject's participation in the clinical study. "These results demonstrate significant improvement in efficacy without compromising patient safety. We believe that AC5 represents a unique technology that will provide both rapid and sustained hemostasis and important differentiable clinical benefits," concluded Norchi. Arch's clinical advisory committee has deemed the study results to be clinically significant and have recommended submitting a manuscript to a peer-reviewed medical journal for publication. The Company expects to submit further study details and data, including subgroup analysis, to a peer-reviewed journal for publication. The Company also plans to include data from this trial in a CE mark application for AC5, which is currently anticipated to be filed at the earliest by the end of this year. Arch is currently planning its next clinical-regulatory steps for both the EU and the US. Professor Abhay Pandit, Director of CÚRAM, said: “Clinical trials are an essential component in creating medical devices that realise their full potential and ensuring the safety value of each new development. Without these trials, research cannot be translated into economic, health or societal benefits. Our collaboration with Arch Therapeutics is very exciting. Leaders within CÚRAM have a successful history working with Arch, and we are delighted to support their drive to commercialization for what should be very important products for the healthcare industry.” -Ends-


News Archive

Monday, 22 August 2016

The Kennedy Summer School, a festival of Irish and American history, culture and politics, will be held in New Ross, Co. Wexford from 8-10 September and will have a distinct NUI Galway flavour in the midst of a hotly contested US presidential election between Donald Trump and Hillary Clinton. The summer school’s guest of honour and featured speaker will be a 2008 honorary graduate of NUI Galway, former Governor of Maryland and Mayor of Baltimore, Martin O’Malley. Governor O’Malley has strong Galway roots and still has a number of cousins living in Connemara. He will deliver the Edward M. Kennedy Memorial Lecture on Friday, 9 September, entitled ‘Supported by her exiled children: Ireland and America, 1916-2016’. Also speaking will be Larry Donnelly, a Lecturer and Director of Clinical Legal Education in NUI Galway’s School of Law and a regular media contributor on American and Irish politics, current affairs and law. He will give a presentation outlining the Electoral College map and the respective paths to the White House for Donald Trump and Hillary Clinton, as well as considering what impact the 2016 election will have on American politics in the longer term. Noel Whelan, Director of the Kennedy Summer School, a barrister and a columnist with The Irish Times, said: “This unique presidential election campaign provides an interesting backdrop for an examination of the Kennedy legacy, the American presidency and what might lie ahead in a time of political uncertainty and upheaval across the western world. “We are delighted to welcome Governor O’Malley to New Ross to hear his insights on the extraordinary relationship between our two countries and the current political landscape. We also are happy to have Larry Donnelly again to expand upon some of the analysis of the Clinton vs. Trump matchup he has provided in the media recently. And on Saturday afternoon of the summer school, both will join Tad Devine, chief strategist of Senator Bernie Sanders’ remarkable bid for the Democratic presidential nomination, Boston Globe columnist Kevin Cullen and others for what we believe will be a fascinating panel discussion on this year’s election.” More information about the Kennedy Summer School is available at www.kennedysummerschool.ie. -Ends-

Monday, 22 August 2016

CAO Points Increase Significantly for Commerce, Science and Health Sciences at NUI Galway The continuing popularity of NUI Galway was reflected by CAO offers issued today, with the vast majority of courses maintaining or increasing points from 2015. Across all five colleges, points have risen. Commerce (Global Experience), Biomedical Science, Biopharmaceutical Chemistry, Biomedical Engineering, Occupational Therapy, and Speech and Language Therapy, all require 500 points or more for entry. Arts (Psychology), Commerce (International) with French, with German and with Spanish, Commerce (Accounting), Financial Mathematics and Economics, and Mathematical Science, all finish in the high 400s. NUI Galway’s Admissions Officer, Stephen O’Dea, said: “For the fourth year running, NUI Galway’s courses in Commerce have seen a steady increase in their points indicating a continued growth in interest in these areas. International Commerce programmes continue to be a popular choice for students with a global outlook and the strong performance of the new Commerce (Global Experience) confirms this. NUI Galway’s strength and reputation in Biosciences is also reflected with Biomedical Science continuing to perform well (530 points) and Biopharmaceutical Chemistry maintaining its 500 points entry requirement. There has been a steady interest in the Financial Mathematics and Economics programme at 485 points. This is reflective of a growing confidence in the national and international economies and financial markets, and growth in employment opportunities therein, both at home and abroad.” This year to assist high-achieving, school leavers from Ireland’s newest communities, such as refugees, to achieve their third-level goals with NUI Galway a new national pilot scheme have been put in place. Four students will be offered places as part of NUI Galway’s new merit-based Inclusive Centenaries Scholarship Scheme. Students have until Friday, 2 September to apply and can visit www.nuigalway.ie/scholarships for details. Stephen concluded: “Incoming students will be well placed to benefit from NUI Galway’s significant and ongoing capital investment programme and its fostering of innovation, entrepreneurship and research. NUI Galway is a diverse community and this year we are delighted to provide scholarship support to benefit members of Ireland’s newest communities to help to realise their full potential.”   With NUI Galway anticipating an intake of over 3,000 new students in September, a hotline is in place for students, parents and teachers. The First Year Student Hotline number is 091 493999 or visit http://www.nuigalway.ie/startinguniversity/ . The hotline will be available from Monday to Friday, 9am to 6pm, and on Saturday, 27 August from 9am to 1pm. Courses on the rise: Prospective students have shown particular interest in Commerce programmes, especially those with an international focus, reflecting awareness of the need for language mobility in the global jobs market. NUI Galway’s three International Commerce programmes (French German, and Spanish) all reached 480 points and NUI Galway’s new programme Commerce (Global Experience) is particularly popular, opening with a points requirement of 500. For the first year, Shannon College of Hotel Management’s course offerings fall within NUI Galway’s programme portfolio, with both Business Studies in International Hotel Management and Commerce in International Hotel Management showing points increases. Biomedical Engineering reached 500 points for the first time. Computer Science and Information Technology remains popular, maintaining its 2015 points requirement of 425, as do Business Information Systems (430 points) and Commerce (Accounting) (460 points). The popularity of NUI Galway’s two Law programmes continues with Corporate Law ending on 385 points and Civil Law on 435 points. Demand for Science courses has increased, with entry to Bachelor of Science Programme up 10 points to 400. Recognising NUI Galway’s national and international leadership in Biosciences, Biomedical Science remains at 530 point, the University’s second highest points programme. Biopharmaceutical Chemistry remains at 500 points, while Biotechnology finished at 440. Entry onto the medical programme requires 723 points (including HPAT), the same as 2015, and General Nursing finished at 445, Psychiatric Nursing at 415 and Midwifery at 440. Both of NUI Galway’s Therapy programmes, Occupational and Speech and Language finished at 530 points. In Arts, NUI Galway’s popular Creative Writing degree continues to attract a great deal of interest with the points increasing by 20 to 445. Arts (Mathematics and Education) has increased in demand with a 25 point rise to 435 and NUI Galway’s new Arts Degree (Children’s Studies) opens at 350 points. -Ends- An-éileamh ar OÉ Gaillimh arís agus tairiscintí an CAO ag teacht amach  Ardú mór ar Phointí an do chúrsaí Tráchtála, Eolaíochta agus Eolaíochtaí Sláinte OÉ Gaillimh Ba léir ó na tairiscintí a rinne an CAO inniu go bhfuil an-éileamh ar OÉ Gaillimh arís i mbliana. Tá líon na bpointí atá de dhíth ar fhormhór mór na gcúrsaí gan athrú nó ardaithe ó 2015. D'ardaigh líon na bpointí atá ag teastáil chun cúrsaí a dhéanamh i gcúig choláiste na hOllscoile. Tá 500 pointe nó níos mó ag teastáil chun áit a fháil sa Tráchtáil (Taithí Idirnáisiúnta), an Eolaíocht Bhithleighis, an Cheimic Bhithchógaisíochta, an Innealtóireacht Bhithleighis, an Teiripe Shaothair agus an Teiripe Urlabhra agus Teanga. Tá níos mó ná 400 pointe ag teastáil i gcás cúrsaí sna Dána (an tSíceolaíocht), an Tráchtáil (Idirnáisiúnta) le Fraincis, Gearmáinis nó Spáinnis, an Tráchtáil (Cuntasaíocht), Matamaitic an Airgeadais agus Eacnamaíocht agus Eolaíochtaí Matamaiticiúla. Tabharfaidh OÉ Gaillimh áit do cheathrar mac léinn mar chuid den Scéim nua Scoláireachtaí Uileghabhálacha Comórtha Céad Bliain a bhronnfar ar bhonn fiúntais i mbliana. Cabhróidh an scéim phíolótach náisiúnta seo le daoine sárchumasacha atá ag fágáil na meánscoile agus arb as nua-phobail na hÉireann iad (teifigh, mar shampla) oideachas tríú leibhéal a bhaint amach in OÉ Gaillimh. Beidh go dtí Dé hAoine, an 2 Meán Fómhair ag mic léinn chun iarratas a dhéanamh agus tá tuilleadh eolais ar fáil ag www.nuigalway.ie/scholarships. Dúirt Oifigeach Iontrála OÉ Gaillimh, Stephen O’Dea: “Siod é an ceathrú bliain as a chéile a tháinig ardú ar líon na bpointí atá de dhíth chun cúrsaí Tráchtála a dhéanamh in OÉ Gaillimh, rud a léiríonn go bhfuil an tsuim sna cúrsaí seo ag méadú léi. Is iomaí mac léinn a bhfuil spéis acu ina bhfuil ag tarlú sa domhan mór a roghnaíonn an cúrsa Tráchtála Idirnáisiúnta agus léiríonn an chaoi ar éirigh leis an gcúrsa nua sa Tráchtáil (Taithí Idirnáisiúnta) sin. Léiríonn an t-ardú ar na pointí don chlár Innealtóireachta Neamhainmnithe i mbliana go dtuigeann mic léinn an fiúntas atá le céim Innealtóireachta a dhéanamh in OÉ Gaillimh, go háirithe i bhfianaise mhargadh iomaíoch fostaíochta an lae inniu. Is léiriú ar láidreacht agus ar cháil OÉ Gaillimh san eolaíocht bhitheach an tóir atá i gcónaí ar an Eolaíocht Bhithleighis (530 pointe) agus ar an gCeimic Bhithchógaisíochta (500 pointe). Tá suim á cur sa chúrsa Matamaitic an Airgeadais agus Eacnamaíocht go leanúnach agus tá 485 pointe de dhíth chun áit a fháil ar an gcúrsa. Léiríonn sé seo go bhfuil an muinín atá ag daoine sa gheilleagar náisiúnta agus idirnáisiúnta agus as na margaí airgeadais ag fás agus go bhfuiltear ag súil go mbeidh deiseanna fostaíochta sna réimsí sin in Éirinn agus thar sáile." Mar fhocal scoir, bhí an méid seo le rá aige: Bainfidh mic léinn tairbhe as an gclár suntasach leanúnach infheistíochta caipitil in OÉ Gaillimh a chuireann ar chumas na foirne agus na mac léinn aghaidh a thabhairt ar nuálaíocht, ar fhiontraíocht agus ar thaighde. Is pobal ilghnéitheach in OÉ Gaillimh agus tá áthas orainn scoláireachtaí a chur ar fáil i mbliana chun cabhrú le baill phobail nua na hÉireann chun barr a gcumais a bhaint amach."  Tá OÉ Gaillimh ag súil go mbeidh 3,000 mac léinn nua ag teacht chuici i Mí Mheán Fómhair agus tá beolíne ar fáil do mhic léinn, tuismitheoirí agus múinteoirí. Is í uimhir Bheolíne Mhic Léinn na Chéad Bhliana 091 493999 nó téigh chuig http://www.nuigalway.ie/new-students/. Beidh an bheolíne ar fáil ó Luan go hAoine, ó 9am go dtí 6pm agus ar an Satharn, an 27 Lúnasa, ó 9am go dtí 1pm. Cúrsaí a bhfuil borradh ag teacht fúthu: Léirigh mic léinn nua suim ar leith sna cláir Tráchtála, go háirithe na cláir a bhfuil gné idirnáisiúnta ag baint leo, rud a thaispeánann go dtuigeann an pobal mór an tábhacht a bhaineann leis an ilteangachas sa mhargadh domhanda fostaíochta. Bhain na Cláir Tráchtála Idirnáisiúnta (Fraincis, Gearmáinis agus Spáinnis) a chuireann OÉ Gaillimh ar fáil 480 pointe amach agus bhí an-tóir ar an gclár nua sa Tráchtáil (Taithí Idirnáisiúnta) agus tá 500 pointe de dhíth chun áit a fháil air. Tá cúrsaí Choláiste Ósta na Sionna i measc na gcúrsaí atá luaite le OÉ Gaillimh den chéad uair i mbliana agus tháinig ardú ar líon na bpointí atá ag teastáil don Staidéar Gnó sa Bhainistíocht Óstáin Idirnáisiúnta agus don Tráchtáil sa Bhainistíocht Óstáin Idirnáisiúnta. D'ardaigh líon na bpointí atá ag teastáil chun áit a fháil ar an gcúrsa Innealtóireachta Neamhainmnithe go 445 i mbliana, rud a léiríonn an tsuim atá ag daoine ar fud na tíre sa réimse seo agus bhain an Innealtóireacht Bhithleighis 500 pointe amach den chéad uair riamh. Tá éileamh ar an Eolaíocht Ríomhaireachta agus  Teicneolaíocht na Faisnéise go fóill agus tá 425 pointe de dhíth chun áit a fháil ar na cúrsaí sin agus is amhlaidh atá sé do Chórais Faisnéise Gnó (430 pointe) agus don Tráchtáil (Cuntasaíocht) (460 pointe). Tá an-tóir ar chláir Dlí OÉ Gaillimh agus tá 385 pointe de dhíth chun an Dlí Corparáideach a dhéanamh agus 435 i gcás an Dlí Shibhialta. Mhéadaigh an t-éileamh ar chúrsaí Eolaíochta agus tá 400 pointe de dhíth chun áit a fháil orthu, méadú 10 bpointe. Ní haon ionadh gurb é an cúrsa Eolaíochta Bithleighis an dara cúrsa is mó a bhfuil pointí ag dul leis (530 pointe) toisc go bhfuil OÉ Gaillimh go mór chun cinn i réimse na nEolaíochtaí Bitheacha go náisiúnta agus go hidirnáisiúnta. Tá 500 pointe de dhíth chun áit a fháil sa Cheimic Bhithchógaisíochta agus 440 i gcás na Biteicneolaíochta. Tá 723 pointe (HPAT san áireamh) ag teastáil chun áit a fháil ar an gclár Leighis, mar a bhí in 2015, agus 445 de dhíth chun an tAltranas Ginearálta a dhéanamh, 415 don Altranas Síciatrach agus 440 don Chnáimhseachas. Tá 530 pointe de dhíth chun áit a fháil ar an dá chlár teiripe a chuireann OÉ Gaillimh ar fáil, an Teiripe Shaothair agus an Teiripe Urlabhra agus Teanga. Maidir leis na Dána, cuireadh an-suim sa chéim sa Scríbhneoireacht Cruthaitheach. Tháinig ardú 20 pointe air agus 445 de dhíth chun áit a fháil ar an gclár.  Tháinig ardú 25 pointe ar an gcúrsa sna Dána (Matamaitic agus Oideachas) agus tá 435 ag teastáil chun áit a fháil air agus tá 350 pointe de dhíth i gcás na céime nua sna Dána (Staidéar Leanaí). -Críoch-

Thursday, 18 August 2016

NUI Galway recently hosted the second International Conference on Pollution Control and Resource Recovery for the Livestock Sector (LivestockWaste2016). The conference provided a forum for researchers and industry representatives to present, discuss and develop their innovative technologies and practices for managing livestock waste and recovering resources. Sponsored by Science Foundation Ireland, Environmental Protection Agency, Engineers Ireland, Teagasc, NUI Galway’s Ryan Institute and Fáilte Ireland, the conference also facilitated the introduction of many innovative international solutions to representatives of the Irish livestock sector and engineering industry with the aim of improving practices in Ireland. Professor Xinmin Zhan, Chair of LivestockWaste2016 and Professor with NUI Galway’s Civil Engineering, said: “In recent years, economic development, population growth and demand for a better quality of living have resulted in the growth of the livestock sector. As a by-product of the sectors activities, a large volume of waste is generated making the livestock sector one of the largest agricultural pollution sources in most developing and developed countries. In addition to the waste generated, the livestock sector is a major contributor to climate change as a result of greenhouse gas (GHG) emissions from rumen animals, on-farm activities and animal waste management. In order to alleviate the pollution from the sector, innovative technologies and practices for managing livestock waste and emissions are being developed worldwide.” Over the three days international renowned experts delivered keynote speeches on a number of critical topics relating to waste management within the Livestock sector including: Professor Kornelia Smalla, The Julius Kühn Institute, Germany; Dr Karl Richards, Teagasc, Johnstown Castle; Professor Han-Qing Yu, University of Science and Technology of China; Dr Jerry Murphy, University College Cork; Professor Xia Huang, Tsinghua University, China; and Professor Dave Chadwick, Bangor University in Wales. In addition, the international conference delegates delivered, both, oral and poster presentations, over the three days. These presentation were grouped under a number of thematic areas, including but limited to: pollution policies and regulations for the livestock sector; emerging contaminants in livestock waste streams; technologies for waste prevention; anaerobic digestion and composting; pollution control technologies; Greenhouse Gas emissions; technologies for nutrient recovery; and other relative technologies. The Environmental Engineering Research Group in Civil Engineering has been very active in carrying out research and practice in environmentally sustainable agricultural waste management. Professor Xinmin Zhan, who chaired the LivestockWaste2016 conference, is leading the GreenFarm project funded by SFI. The project explores the technical and financial feasibility of anaerobic co-digestion plants on Irish pig farms, and the DairyWater project investigating measures to increase the environmental sustainability of the Irish dairy processing industry. -Ends-


Events Calendar

Upcoming Events Time / Date Location
HRB Clinical Research Facility OPENHOUSE 16.00 Thursday,
1 September 2016
HRB Clinical Research Facility Galway

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