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University Life
University Life
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About University of Galway
About University of Galway
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Guiding Breakthrough Research at University of Galway
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Community Engagement
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Medicine
Dr Norashikin Zakaria
BSc, PhD
Contact Details
Post Doctoral Researcher
E: Norashikin.Zakaria@universityofgalway.ie
E: Norashikin.Zakaria@universityofgalway.ie
Postdoctoral researcher
Clinical Pharmacology
The Lambe Institute For Translational Research
Ireland
T: +353899894620
E: norashikin.zakaria@universityofgalway.ie
Clinical Pharmacology
The Lambe Institute For Translational Research
Ireland
T: +353899894620
E: norashikin.zakaria@universityofgalway.ie
Biography
Peer Reviewed Journals
| Year | Publication | |
|---|---|---|
| (2022) | 'Discovering triple negative breast cancers (TNBC) transcriptomic profiles via massive screening of single cell RNA-sequencing (scRNA-seq) datasets'
Rafsanjani, Mohd Rifqi and Onn, Muhammad Asyraf and Zakaria, Norashikin (2022) 'Discovering triple negative breast cancers (TNBC) transcriptomic profiles via massive screening of single cell RNA-sequencing (scRNA-seq) datasets'. bioRxiv, :2022-07 [Details] |
|
| (2021) | 'Human umbilical cord mesenchymal stem cell-derived extracellular vesicles ameliorate airway inflammation in a rat model of chronic obstructive pulmonary disease (COPD)'
Ridzuan, Noridzzaida and Zakaria, Norashikin and Widera, Darius and Sheard, Jonathan and Morimoto, Mitsuru and Kiyokawa, Hirofumi and Mohd Isa, Seoparjoo Azmel and Chatar Singh, Gurjeet Kaur and Then, Kong-Yong and Ooi, Ghee-Chien and others (2021) 'Human umbilical cord mesenchymal stem cell-derived extracellular vesicles ameliorate airway inflammation in a rat model of chronic obstructive pulmonary disease (COPD)'. Stem cell research \& therapy, 12 (1):1-21 [Details] |
|
| (2021) | 'The Effects of Lentivirus-Mediated Gene Silencing of RAR$\beta$ on the Stemness Capability of Non-Small Cell Lung Cancer'
Halim, Noor Hanis Abu and Zakaria, Norashikin and Das, Kumitaa Theva and Lin, Juntang and Lim, Moon Nian and Fakiruddin, Kamal Shaik and Yahaya, Badrul Hisham (2021) 'The Effects of Lentivirus-Mediated Gene Silencing of RAR$\beta$ on the Stemness Capability of Non-Small Cell Lung Cancer'. Journal of Cancer, 12 (12) [Details] |
|
| (2021) | 'Unlocking effective transgene expression potential in gene therapy with viral vectors'
Halim, Nur Shuhaidatul Sarmiza Abdul and Halim, Noor Hanis Abu and Vengidasan, Lelamekala and Zakaria, Norashikin and Ismail, Ida Shazrina and Yahaya, Badrul Hisham (2021) 'Unlocking effective transgene expression potential in gene therapy with viral vectors'. Biomedical Research and Therapy, 8 (10):4596-4611 [Details] |
|
| (2020) | 'Acute lung injury: disease modelling and the therapeutic potential of stem cells'
Lian, Jie and Lin, Juntang and Zakaria, Norashikin and Yahaya, Badrul Hisham (2020) 'Acute lung injury: disease modelling and the therapeutic potential of stem cells'. Cell Biology and Translational Medicine, Volume 10: Stem Cells in Tissue Regeneration, :149-166 [Details] |
|
| (2018) | 'Novel triple-positive markers identified in human non-small cell lung cancer cell line with chemotherapy-resistant and putative cancer stem cell characteristics'
Satar, Nazilah Abdul and Fakiruddin, Kamal Shaik and Lim, Moon Nian and Mok, Pooi Ling and Zakaria, Norashikin and Fakharuzi, Noor Atiqah and Abd Rahman, Ahmad Zuhairi and Zakaria, Zubaidah and Yahaya, Badrul Hisham and Baharuddin, Puteri (2018) 'Novel triple-positive markers identified in human non-small cell lung cancer cell line with chemotherapy-resistant and putative cancer stem cell characteristics'. Oncology reports, 40 (2):669-681 [Details] |
|
| (2018) | 'Inhibition of NF-$\kappa$B signaling reduces the stemness characteristics of lung cancer stem cells'
Zakaria, Norashikin and Mohd Yusoff, Narazah and Zakaria, Zubaidah and Widera, Darius and Yahaya, Badrul Hisham (2018) 'Inhibition of NF-$\kappa$B signaling reduces the stemness characteristics of lung cancer stem cells'. Frontiers in oncology, 8 [Details] |
|
| (2017) | 'The use of mesenchymal stromal cells in treatment of lung disorders'
Kardia, Egi and Zakaria, Norashikin and Sarmiza Abdul Halim, Nur Shuhaidatul and Widera, Darius and Yahaya, Badrul Hisham (2017) 'The use of mesenchymal stromal cells in treatment of lung disorders'. Regenerative medicine, 12 (2):203-216 [Details] |
|
| (2017) | 'Targeting lung cancer stem cells: research and clinical impacts'
Zakaria, Norashikin and Satar, Nazilah Abdul and Abu Halim, Noor Hanis and Ngalim, Siti Hawa and Yusoff, Narazah Mohd and Lin, Juntang and Yahaya, Badrul Hisham (2017) 'Targeting lung cancer stem cells: research and clinical impacts'. Frontiers in oncology, 7 [Details] |
|
| (2016) | 'Curcumin improves the efficacy of cisplatin by targeting cancer stem-like cells through p21 and cyclin D1-mediated tumour cell inhibition in non-small cell lung cancer cell lines'
Baharuddin, Puteri and Satar, Nazilah and Fakiruddin, Kamal Shaik and Zakaria, Norashikin and Lim, Moon Nian and Yusoff, Narazah Mohd and Zakaria, Zubaidah and Yahaya, Badrul Hisham (2016) 'Curcumin improves the efficacy of cisplatin by targeting cancer stem-like cells through p21 and cyclin D1-mediated tumour cell inhibition in non-small cell lung cancer cell lines'. Oncology reports, 35 (1):13-25 [Details] |
|
| (2016) | 'Isolation and characterization of cancer stem cells of the non-small-cell lung cancer (A549) cell line'
Halim, Noor Hanis Abu and Zakaria, Norashikin and Satar, Nazilah Abdul and Yahaya, Badrul Hisham (2016) 'Isolation and characterization of cancer stem cells of the non-small-cell lung cancer (A549) cell line'. Stem Cell Heterogeneity: Methods and Protocols, :371-388 [Details] |
|
| (2015) | 'Human non-small cell lung cancer expresses putative cancer stem cell markers and exhibits the transcriptomic profile of multipotent cells'
Zakaria, Norashikin and Yusoff, Narazah Mohd and Zakaria, Zubaidah and Lim, Moon Nian and Baharuddin, Puteri J Noor and Fakiruddin, Kamal Shaik and Yahaya, Badrul (2015) 'Human non-small cell lung cancer expresses putative cancer stem cell markers and exhibits the transcriptomic profile of multipotent cells'. BMC cancer, 15 (1):1-16 [Details] |
Book Chapters
| Year | Publication | |
|---|---|---|
| (2023) | 'The Rapid Development of Airway Organoids: A Direct Culture Strategy'
Shaffi, Syahidatulamali Che and Zakaria, Norashikin and Halim, Nur Shuhaidatul Sarmiza Abdul and Ishtiah, Anan A and Patar, Azim Ab and Yahaya, Badrul Hisham (2023) 'The Rapid Development of Airway Organoids: A Direct Culture Strategy' In: Springer. [Details] |
Conference Publications
| Year | Publication | |
|---|---|---|
| (2020) | Cancer Biology and Advances in Treatment
Zakaria, Norashikin and Yahaya, Badrul Hisham (2020) Adipose-derived mesenchymal stem cells promote growth and migration of lung adenocarcinoma cancer cells Cancer Biology and Advances in Treatment , pp.83-95 [Details] |
|
| (2016) | Front. Bioeng. Biotechnol. Conference Abstract: 6th Malaysian Tissue Engineering and Regenerative Medicine Scientific Meeting (6th MTERMS) 2016 and 2nd Malaysian Stem Cell Meeting. doi: 10.3389/conf. FBIOE
Halim, Noor Hanis Abu and Zakaria, Norashikin and Yahaya, Badrul Hisham (2016) Isolation and characterisation of CD166+/EpCAM+ and CD166+/CD44+ as markers for cancer stem cells from non-small cell lung cancer of A549 Front. Bioeng. Biotechnol. Conference Abstract: 6th Malaysian Tissue Engineering and Regenerative Medicine Scientific Meeting (6th MTERMS) 2016 and 2nd Malaysian Stem Cell Meeting. doi: 10.3389/conf. FBIOE [Details] |
Honours and Awards
| Year | Title | Awarding Body | |
|---|---|---|---|
| 2018 | Research Excellence Award | Malaysia Science University | |
| 2017 | Best Postgraduate Student Award | Malaysia Science University | |
| 2014 | Sanggar Kencana Award | Malaysia Science University | |
| 2014 | 1st Place Presenter Award | International Conference on Medical & Health Sciences | |
| 2014 | USM Fellowship Scheme | Malaysia Science University |
Employment
| Employer | Position | From / To | |
|---|---|---|---|
| Malaysia Science University | Graduate Reseach Assistant | 15-OCT-12 / 15-OCT-16 | |
| Malaysia Science University | Research Assistant | 01-OCT-21 / 31-MAR-22 | |
| Institute for Medical Research (IMR), Malaysia | Research Assistant | 01-MAR-12 / 30-SEP-12 | |
| Malaysia Science University | Post-doctoral Research Fellow | 01-OCT-18 / 29-FEB-20 |
Education
| Year | Institution | Qualification | Subject | |
|---|---|---|---|---|
| 2011 | University Malaysia Sabah | BSc. (Hons) | Biotechnology | |
| 2017 | Malaysia Science University | PhD | Cancer Genetics |
Languages
| Language | |
|---|---|
| English |
Reviews
| Journal | Role | |
|---|---|---|
| Scientific Reports | Reviewer |
