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Medicine

Dr Róisín Dwyer

BSc, MSc, PhD

Contact Details

Lecturer In Translational Science
Surgery
Office 2.15
2nd Floor
Lambe Institute for Translational Research
NUI Galway

T: +353 (0)91 493008
F: +353 (0)91 494509
E: roisin.dwyer@nuigalway.ie
 
researcher

Biography

Róisín Dwyer is a Lecturer in Translational Science in the Discipline of Surgery at NUI Galway. Following graduation from UCD with a degree in Science, Róisín went on to complete an MSc in Biological Sciences at DCU, and then was awarded her PhD in Medicine and Therapeutics from UCD. Róisín's research background in breast cancer led to a 3 year postdoctoral research position at the Mayo Clinic, Rochester, Minnesota. Upon her return to Ireland, she was awarded a National University of Ireland (NUI) Postdoctoral Fellowship in the Sciences, and joined the research team of Professor Michael Kerin in the National Breast Cancer Research Institute (NBCRI) at NUI Galway. She received Health Research Board funding in 2007, and a subsequent Project Grant awarded by the Irish Cancer Society in 2008. She was named Irish Cancer Society "Researcher of the Year" in 2012. Róisín's current research, in collaboration with both national and international research groups, focuses on novel approaches to breast cancer therapy. Her work investigates the potential of adult stem cells as vehicles for targeted delivery of therapeutic agents to breast tumours, with a specific interest in imaging modalities to track their migration in vivo. Other areas of interest include cellular interactions in the breast tumour microenvironment mediated by cytokines and microRNAs.

Peer Reviewed Journals

  Year Publication
(2010) 'Potential role of mesenchymal stem cells (MSCs) in the breast tumour microenvironment: stimulation of epithelial to mesenchymal transition (EMT)'
Martin FT, Dwyer RM, Kelly J, Khan S, Murphy JM, Curran C, Miller N, Hennessy E, Dockery P, Barry FP, O'Brien T, Kerin MJ. (2010) 'Potential role of mesenchymal stem cells (MSCs) in the breast tumour microenvironment: stimulation of epithelial to mesenchymal transition (EMT)'. Breast Cancer Res Treat, 124 (2):317-26 [Details]
(2011) 'Mesenchymal Stem Cell-Mediated Delivery of the Sodium Iodide Symporter (NIS) Supports Radionuclide Imaging and Treatment of Breast Cancer'
Dwyer RM, Ryan J, Havelin RJ, Morris JC, Miller BW, Liu Z, Flavin R, O'Flatharta C, Foley MJ, Barrett HH, Murphy JM, Barry FP, O'Brien T, Kerin MJ. (2011) 'Mesenchymal Stem Cell-Mediated Delivery of the Sodium Iodide Symporter (NIS) Supports Radionuclide Imaging and Treatment of Breast Cancer'. Stem Cells, 29 :1149-57 [Details]
(2013) 'miR-379 Regulates Cyclin B1 Expression and Is Decreased in Breast Cancer'
Khan, S,Brougham, CL,Ryan, J,Sahrudin, A,O'Neill, G,Wall, D,Curran, C,Newell, J,Kerin, MJ,Dwyer, RM (2013) 'miR-379 Regulates Cyclin B1 Expression and Is Decreased in Breast Cancer'. Plos One, 8 [DOI] [Details]
(2013) 'Objective assessment of image quality VI: imaging in radiation therapy'
Barrett, HH,Kupinski, MA,Mueller, S,Halpern, HJ,Morris, JC,Dwyer, R (2013) 'Objective assessment of image quality VI: imaging in radiation therapy'. Physics In Medicine And Biology, 58 :8197-8213 [DOI] [Details]
(2015) 'Solvent-selective routing for centrifugally automated solid-phase purification of RNA'
Dimov, N., Clancy, E., Gaughran, J., Boyle, D, McAuley, D., Glynn, M.T., Dwyer, R., Coughlan, H., Barry, T., Barrett, L.M., Smith, T.J. and Ducree, J. (2015) 'Solvent-selective routing for centrifugally automated solid-phase purification of RNA'. Microfluidics And Nanofluidics, 18 (5):859-871 [DOI] [ARAN Link] [Details]
(2014) 'Impact of Tumour Epithelial Subtype on Circulating microRNAs in Breast Cancer Patients'
Waters PS, Dwyer RM, Brougham C, Glynn CL, Wall D, Hyland P, Duignan M, McLoughlin M, Newell J, Kerin MJ (2014) 'Impact of Tumour Epithelial Subtype on Circulating microRNAs in Breast Cancer Patients'. Plos One, 9 (3) [DOI] [Details]
(2013) 'Design and performance of a small-animal imaging system using synthetic collimation'
Havelin RJ, Miller BW, Barrett HH, Furenlid LR, Murphy JM, Dwyer RM, Foley MJ (2013) 'Design and performance of a small-animal imaging system using synthetic collimation'. Physics In Medicine And Biology, 58 (10):3397-3412 [DOI] [ARAN Link] [Details]
(2013) 'Impact of Mesenchymal Stem Cell Secreted PAI-1 on Colon Cancer Cell Migration and Proliferation'
Hogan NM, Joyce MR, Murphy JM, Barry FP, O'Brien T, Kerin MJ, Dwyer RM (2013) 'Impact of Mesenchymal Stem Cell Secreted PAI-1 on Colon Cancer Cell Migration and Proliferation'. Biochem Biophy Res Commun, [DOI] [Details]
(2012) 'Isolation of secreted microRNAs (miRNAs) from cell-conditioned media'
Glynn C, Khan S, Kerin MJ and Dwyer RM. (2012) 'Isolation of secreted microRNAs (miRNAs) from cell-conditioned media'. MicroRNA, [ARAN Link] [Details]
(2012) 'Relationship between Circulating and Tissue microRNAs in a Murine Model of Breast Cancer'
Waters, PS,McDermott, AM,Wall, D,Heneghan, HM,Miller, N,Newell, J,Kerin, MJ,Dwyer, RM (2012) 'Relationship between Circulating and Tissue microRNAs in a Murine Model of Breast Cancer'. Plos One, 7 [DOI] [Details]
(2012) 'Influence of stromal-epithelial interactions on breast cancer in vitro and in vivo'
Potter, SM,Dwyer, RM,Hartmann, MC,Khan, S,Boyle, MP,Curran, CE,Kerin, MJ (2012) 'Influence of stromal-epithelial interactions on breast cancer in vitro and in vivo'. Breast Cancer Research And Treatment, 131 :401-411 [DOI] [Details]
(2012) 'Mesenchymal stem cells in the colorectal tumor microenvironment: Recent progress and implications'
Hogan, NM,Dwyer, RM,Joyce, MR,Kerin, MJ (2012) 'Mesenchymal stem cells in the colorectal tumor microenvironment: Recent progress and implications'. International Journal Of Cancer, 131 (1):1-7 [DOI] [Details]
(2011) 'The sodium iodide symporter (NIS) and potential regulators in normal, benign and malignant human breast tissue'
Ryan J, Curran CE, Hennessy E, Newell J, Morris JC, Kerin MJ, Dwyer RM. (2011) 'The sodium iodide symporter (NIS) and potential regulators in normal, benign and malignant human breast tissue'. Plos One, 6 (1) [Details]
(2011) 'Relationship between CCL5 and transforming growth factor-β1 (TGFβ1) in breast cancer'
Hartmann MC, Dwyer RM, Costello M, Potter SM, Curran C, Hennessy E, Newell J, Griffin DG, Kerin MJ (2011) 'Relationship between CCL5 and transforming growth factor-β1 (TGFβ1) in breast cancer'. European Journal Of Cancer, 47 (11):1669-1675 [DOI] [Details]
(2010) 'Advances in mesenchymal stem cell-mediated gene therapy for cancer'
Dwyer RM, Khan S, Barry FP, O'Brien T and Kerin MJ (2010) 'Advances in mesenchymal stem cell-mediated gene therapy for cancer'. Stem Cell Research And Therapy, 1 (3) [Details]
(2010) 'Dysregulated miR-183 inhibits migration in breast cancer cells'
Lowery, AJ, Miller, N, Dwyer, RM, Kerin, MJ (2010) 'Dysregulated miR-183 inhibits migration in breast cancer cells'. BMC Cancer, 10 [DOI] [Details]
(2010) 'Mesenchymal Stem Cells (MSCs) and Cancer: tumour specific delivery vehicles or therapeutic targets?'
Dwyer RM Kerin MJ (2010) 'Mesenchymal Stem Cells (MSCs) and Cancer: tumour specific delivery vehicles or therapeutic targets?'. Human Gene Therapy, 21 (11):1506-1512 [Details]
(2009) 'Sodium iodide symporter (NIS) mediated tracking of mesenchymal stem cell (MSC) migration to breast tumours in vivo'
Dwyer R et al. (2009) 'Sodium iodide symporter (NIS) mediated tracking of mesenchymal stem cell (MSC) migration to breast tumours in vivo'. Human Gene Therapy, 20 (11) [Details]
(2009) 'Mesenchymal stem cell secretion of chemokines during differentiation into osteoblasts, and their potential role in mediating interactions with breast cancer cells'
Molloy, AP,Martin, FT,Dwyer, RM,Griffin, TP,Murphy, M,Barry, FP,O'Brien, T,Kerin, MJ (2009) 'Mesenchymal stem cell secretion of chemokines during differentiation into osteoblasts, and their potential role in mediating interactions with breast cancer cells'. International Journal Of Cancer, 124 :326-332 [DOI] [Details]
(2009) 'Systemic chemokine levels in breast cancer patients and their relationship with circulating menstrual hormones'
Potter, SM,Dwyer, RM,Curran, CE,Hennessy, E,Harrington, KA,Griffin, DG,Kerin, MJ (2009) 'Systemic chemokine levels in breast cancer patients and their relationship with circulating menstrual hormones'. Breast Cancer Research And Treatment, 115 :279-287 [DOI] [Details]
(2007) 'Monocyte Chemotactic Protein-1 (MCP-1) secreted by primary breast tumors stimulates migration of Mesenchymal Stem Cells (MSCs)'
Dwyer RM, Potter-Beirne SM, Harrington KA, Lowery AJ, Hennessy E, Murphy JM, Barry FP, O'Brien T, Kerin MJ (2007) 'Monocyte Chemotactic Protein-1 (MCP-1) secreted by primary breast tumors stimulates migration of Mesenchymal Stem Cells (MSCs)'. Clinical Cancer Research, 13 (17):5020-5027 [Details]
(2006) 'Sodium Iodide Symporter (NIS)-mediated Radioiodide Imaging and Therapy of Ovarian Tumor Xenografts in Mice'
Bergert ER, Gendler SJ, O'Connor MK and Morris JC (2006) 'Sodium Iodide Symporter (NIS)-mediated Radioiodide Imaging and Therapy of Ovarian Tumor Xenografts in Mice'. Gene Therapy, 13 (1):60-66 [Details]
(2006) 'Adenovirus-mediated and targeted expression of the sodium-iodide symporter permits in vivo radioiodide imaging and therapy of pancreatic tumors'
Bergert ER, Gendler SJ, O'Connor MK and Morris JC (2006) 'Adenovirus-mediated and targeted expression of the sodium-iodide symporter permits in vivo radioiodide imaging and therapy of pancreatic tumors'. Human Gene Therapy, 17 (6):661-668 [Details]
(2005) 'In Vivo Radioiodide Imaging and Treatment of Breast Cancer Xenografts Following MUC1-driven Expression of the Sodium Iodide Symporter (NIS)'
Bergert ER, Gendler SJ, O'Connor MK and Morris JC (2005) 'In Vivo Radioiodide Imaging and Treatment of Breast Cancer Xenografts Following MUC1-driven Expression of the Sodium Iodide Symporter (NIS)'. Cinical Cancer Research, 11 (4):1483-1489 [Details]
(2005) 'A Preclinical Large Animal Model of Adenovirus-Mediated Expression of the Sodium-Iodide Symporter for Radioiodide Imaging and Therapy of Locally Recurrent Prostate Cancer'
Schatz SM, Bergert ER, Myers RM, Harvey ME, Classic KL, Marler RJ, O'Connor MK and Morris JC (2005) 'A Preclinical Large Animal Model of Adenovirus-Mediated Expression of the Sodium-Iodide Symporter for Radioiodide Imaging and Therapy of Locally Recurrent Prostate Cancer'. Molecular Therapy, 12 (5):835-841 [Details]
(2002) 'The Sodium Iodide Symporter and Thyroid Disease'
Smyth PPA (2002) 'The Sodium Iodide Symporter and Thyroid Disease'. Clinical Endocrinology, 56 (4):427-429 [Details]
(2000) 'Tissue Iodine Content and Serum Mediated 125I Uptake Blocking Activity in Breast Cancer'
Kilbane MT, Ajjan RA, Weetman AP, Dwyer R, McDermott EWM, O'Higgins N J and Smyth PPA (2000) 'Tissue Iodine Content and Serum Mediated 125I Uptake Blocking Activity in Breast Cancer'. Journal of Clinical Endocrinology and Metabolism, 85 :1245-1250 [Details]

Book Chapters

  Year Publication
(2013) 'Diagnostic and Therapeutic Mesenchymal stem cells for breast cancer treatment'
Dwyer RM (2013) 'Diagnostic and Therapeutic Mesenchymal stem cells for breast cancer treatment' In: Stem Cell based Therapeutics for Cancer. Hoboken, NJ: John Wiley & Sons. [DOI] [Details]

Conference Publications

  Year Publication
(2008) European Journal of Cancer Supplements 6 (9)
Dwyer, RM,Morris, JC,Murphy, M,Barry, FP,O'Brien, T,Kerin, MJ (2008) Investigation of the potential of mesenchymal stem cells (MSCs) for gene delivery to breast tumours European Journal of Cancer Supplements 6 (9) , pp.27-28 [Details]
(2009) Orthopedics
Molloy AP, Martin FT, Dwyer RM, Griffin TP, Murphy M, Barry FP, O'Brien T, Kerin MJ. (2009) Bone Marrow Derived Mesenchymal Stem Cells Promote Angiogenic Processes in a Time and Dose Dependent Manner In Vitro Orthopedics , pp.2459-2470 [DOI] [Details]
(2009) ??
Potter, S. M.,Dwyer, R. M.,Kerin, M. J. (2009) Stromal-epithelial cell cross-talk in the breast tumour microenvironment elicits changes in tumour epithelial cell gene expression ?? [Details]
(2009) European Journal of Cancer Supplements 7 (2), 89
Kelly, J,Dwyer, RM,Murphy, M,Barry, FP,O'Brien, T,Kerin, MJ (2009) Mesenchymal Stem Cell (MSC) secretion of TGFβ and VEGF stimulates Epithelial to Mesenchymal Transition (EMT) in breast cancer cell lines European Journal of Cancer Supplements 7 (2), 89 [Details]

Abstract

  Year Publication
(2007) Investigation of the potential of human mesenchymal stem cells (hMSC) as vectors for therapeutic gene delivery to breast tumours.
Dwyer, RM,Barry, FP,O'Brien, T,Kerin, MJ (2007) Investigation of the potential of human mesenchymal stem cells (hMSC) as vectors for therapeutic gene delivery to breast tumours. Abstract [Details]
(2007) The potential role of bone derived cells in the development of breast cancer metastases.
Molloy, AP,Dwyer, RM,Kerin, MJ (2007) The potential role of bone derived cells in the development of breast cancer metastases. Abstract [Details]
(2007) Myocardial Infarct-Produced Chemokine Stimulus Promotes Stem Cell Migration. Irish Society for Gene and Cell Therapy, Regenerative Medicine Institute (REMEDI), National University of Ireland, Galway, Ireland.
Kavanagh C, Sloane P, Dwyer R, Coleman CM, O'Brien T, Barry F (2007) Myocardial Infarct-Produced Chemokine Stimulus Promotes Stem Cell Migration. Irish Society for Gene and Cell Therapy, Regenerative Medicine Institute (REMEDI), National University of Ireland, Galway, Ireland. Abstract [Details]
(2007) Myocardial Infarct-Produced Chemokine Stimulus Promotes Stem Cell Migration. Proceedings of the 5th International Society For Stem Cell Research.
Kavanagh C, Sloane P, Dwyer R, Coleman CM, O'Brien T, Barry F (2007) Myocardial Infarct-Produced Chemokine Stimulus Promotes Stem Cell Migration. Proceedings of the 5th International Society For Stem Cell Research. Cairns, Australia: Abstract [Details]
(2007) Distinct chemokines mediate tumourigenicity of breast cancer cells.
Potter, SM,Dwyer, RM,Kerin, MJ (2007) Distinct chemokines mediate tumourigenicity of breast cancer cells. Abstract [Details]
(2007) Osteoblasts and their progenitors stimulate breast cancer cell migration through chemokine secretion.
Molloy, AP,Dwyer, RM,Kerin, MJ (2007) Osteoblasts and their progenitors stimulate breast cancer cell migration through chemokine secretion. Abstract [Details]
(2008) Marrow-derived mesenchymal stem cells (MSCs) stimulate breast cancer cell secretion and expression of chemokines.
Martin, FT,Dwyer, RM,Murphy, JM,Barry, FP,O'Brien, T,Kerin, MJ (2008) Marrow-derived mesenchymal stem cells (MSCs) stimulate breast cancer cell secretion and expression of chemokines. Abstract [Details]
(2008) Investigation of the potential of mesenchymal stem cells (MSCs) for gene delivery to breast tumours.
Dwyer, RM,Morris, JC,Murphy, M,Barry, FP,O'Brien, T,Kenn, MJ (2008) Investigation of the potential of mesenchymal stem cells (MSCs) for gene delivery to breast tumours. Abstract [Details]
(2008) Elevated plasma sdf-1 alpha in breast cancer patients correlates with tumour grade.
Potter, S,Dwyer, R,Harrington, K,Kerin, M (2008) Elevated plasma sdf-1 alpha in breast cancer patients correlates with tumour grade. Abstract [Details]
(2008) Hormonal regulation of breast cancer associated chemokines.
Potter, S,Dwyer, RM,Hennessy, E,Griffin, DG,Kerin, MJ (2008) Hormonal regulation of breast cancer associated chemokines. Abstract [Details]
(2009) Characterization of primary tumour stromal cells and their potential role in the breast cancer microenvironment.
Hartmann, MC,Dwyer, RM,Potter, SM,Dockery, P,Kerin, MJ (2009) Characterization of primary tumour stromal cells and their potential role in the breast cancer microenvironment. Abstract [Details]
(2009) Mesenchymal Stem Cell (MSC) secretion of TGF beta and VEGF stimulates Epithelial to Mesenchymal Transition (EMT) in breast cancer cell lines.
Kelly, J,Dwyer, RM,Murphy, M,Barry, FP,O'Brien, T,Kerin, MJ (2009) Mesenchymal Stem Cell (MSC) secretion of TGF beta and VEGF stimulates Epithelial to Mesenchymal Transition (EMT) in breast cancer cell lines. Abstract [Details]
(2009) Analysis of Primary Breast Tumour Stromal Cells and Their Potential Role in Disease Progression.
Hartmann, MC,Dwyer, RM,Kerin, MJ (2009) Analysis of Primary Breast Tumour Stromal Cells and Their Potential Role in Disease Progression. Abstract [Details]
(2009) EFFECT OF MONOCYTE CHEMOTACTIC PROTEIN-1(MCP-1) ON BREAST CANCER CELL PROLIFERATION AND GENE EXPRESSION.
Hartmann, MC,Dwyer, RM,Boyle, MP,Potter, SM,Kerin, MJ (2009) EFFECT OF MONOCYTE CHEMOTACTIC PROTEIN-1(MCP-1) ON BREAST CANCER CELL PROLIFERATION AND GENE EXPRESSION. Abstract [Details]
(2009) Potential promotion of metastatis of circulating breast cancer cells through interactions with mesenchymal stem cells (MSCs).
Martin, FT,Dwyer, RM,Murphy, MJ,Barry, FP,Brien, TO,Kerin, MJ (2009) Potential promotion of metastatis of circulating breast cancer cells through interactions with mesenchymal stem cells (MSCs). Abstract [Details]
(2009) Stromal-epithelial cell cross-talk in the breast tumour microenvironment elicits changes in tumour epithelial cell gene expression.
Potter, SM,Dwyer, RM,Kerin, MJ (2009) Stromal-epithelial cell cross-talk in the breast tumour microenvironment elicits changes in tumour epithelial cell gene expression. Abstract [Details]
(2010) CORRELATION BETWEEN CIRCULATING AND TUMOUR TISSUE CCL5 AND TGF beta 1 IN BREAST CANCER PATIENTS.
Hartmann, MC,Dwyer, RM,Costello, M,Kerin, MJ (2010) CORRELATION BETWEEN CIRCULATING AND TUMOUR TISSUE CCL5 AND TGF beta 1 IN BREAST CANCER PATIENTS. Abstract [Details]
(2011) Mesenchymal Stem Cell (MSC) mediated delivery of the Sodium Iodide Symporter (NIS) supports radionuclide imaging and treatment of breast cancer. American Association for Cancer Research, Orlando, Florida.
Dwyer RM, Ryan J, Havelin RJ, Morris JC, O'Flatharta C, Miller BW, Liu Z, Foley MJ, Barrett HH, Murphy M, Barry FP, O'Brien T and Kerin MJ (2011) Mesenchymal Stem Cell (MSC) mediated delivery of the Sodium Iodide Symporter (NIS) supports radionuclide imaging and treatment of breast cancer. American Association for Cancer Research, Orlando, Florida. Abstract [Details]
(2012) Identification and Validation of a MicroRNA Signature Associated with Breast Cancer Progression.
Waters, PS,Dwyer, RM,Wall, D,McDermott, AM,Newell, J,Kerin, MJ (2012) Identification and Validation of a MicroRNA Signature Associated with Breast Cancer Progression. Abstract [Details]
(2014) Exosome-mediated active and selective secretion of MicroRNAs by breast cancer cells in vitro.
Rahmani, LS,Glynn, CL,Dwyer, RM,Kerin, MJ (2014) Exosome-mediated active and selective secretion of MicroRNAs by breast cancer cells in vitro. Abstract [Details]
(2014) Secretion of Exosome-Encapsulated MicroRNAs by Basal Breast Cancer Cells in Vitro.
Joyce, D,Glynn, C,Brown, J,Holian, E,Dockery, P,Kerin, MJ,Dwyer, R (2014) Secretion of Exosome-Encapsulated MicroRNAs by Basal Breast Cancer Cells in Vitro. Abstract [Details]
(2014) Exosome-Encapsulated MicroRNAs Secreted by Colorectal Cancer Cells: Mediators of Intercellular Cross-Talk in the Tumour Micro-Environment.
Clancy, C,Brown, J,Holian, E,Joyce, M,Kerin, MJ,Dwyer, RM (2014) Exosome-Encapsulated MicroRNAs Secreted by Colorectal Cancer Cells: Mediators of Intercellular Cross-Talk in the Tumour Micro-Environment. Abstract [Details]
(2014) Secretion of exosome-encapsulated oncomiRs by colorectal cancer cells in vitro.
Clancy, C,Joyce, MR,Kerin, MJ,Dwyer, RM (2014) Secretion of exosome-encapsulated oncomiRs by colorectal cancer cells in vitro. Abstract [Details]
(2014) Investigation of exosome-encapsulated microRNA secretion in breast cancer.
Glynn, C,Khan, S,Brougham, C,Clancy, C,Joyce, D,Dockery, P,Kerin, MJ,Dwyer, RM (2014) Investigation of exosome-encapsulated microRNA secretion in breast cancer. Abstract [DOI] [Details]
(2015) Exosome-mediated trafficking of microRNAs by breast cancer cells.
Joyce, DP,Glynn, CL,Brown, J,Holian, E,Dockery, P,Kerin, MJ,Dwyer, RM (2015) Exosome-mediated trafficking of microRNAs by breast cancer cells. Abstract [Details]
(2015) Exosome-mediated trafficking of microRNAs by basal breast cancer cells in vitro.
Joyce, DP,Glynn, CL,Higgins, M,Brown, J,Holian, E,Dockery, P,Kerin, MJ,Dwyer, RM (2015) Exosome-mediated trafficking of microRNAs by basal breast cancer cells in vitro. Abstract [Details]
(2015) Potential role of photoacoustic imaging in neoadjuvant chemotherapy response monitoring in breast cancer.
Casey, MC,Ennis, R,Walsh, S,Brown, JAL,Dwyer, RM,Leahy, MJ,Kerin, MJ (2015) Potential role of photoacoustic imaging in neoadjuvant chemotherapy response monitoring in breast cancer. Abstract [Details]
(2015) Investigation of exosome-encapsulated microRNAs as potential circulating biomarkers of breast cancer.
Joyce, DP,Higgins, M,Glynn, CL,Brown, J,Holian, E,Dockery, P,Kerin, MJ,Dwyer, RM (2015) Investigation of exosome-encapsulated microRNAs as potential circulating biomarkers of breast cancer. Abstract [Details]
(2015) Secretion of Exosome-Encapsulated MicroRNAs by Breast Cancer Cell Lines.
Joyce, D,Glynn, C,Dockery, P,Dwyer, R,Kerin, M (2015) Secretion of Exosome-Encapsulated MicroRNAs by Breast Cancer Cell Lines. Abstract [Details]
(2015) Investigating a tumour-suppressor role for miR-379 in colorectal cancer.
Clancy, C,Khan, S,Glynn, CL,Joyce, MR,Kerin, MJ,Dwyer, RM (2015) Investigating a tumour-suppressor role for miR-379 in colorectal cancer. Abstract [Details]
(2015) Analysis of Exosome-Encapsulated MicroRNAs Secreted by Mesenchymal Stem Cells in Vitro.
Clancy, C,Brougham, C,Joyce, MR,Dwyer, RM,Kerin, MJ (2015) Analysis of Exosome-Encapsulated MicroRNAs Secreted by Mesenchymal Stem Cells in Vitro. Abstract [Details]

Conference Paper

  Year Publication
(2007) The potential role of bone-derived cells in development of breast cancer metastases. Sir Peter Freyer Surgical Symposium.
AP Molloy, RM Dwyer and MJ Kerin (2007) The potential role of bone-derived cells in development of breast cancer metastases. Sir Peter Freyer Surgical Symposium. Conference Paper [Details]
(2007) Mesenchymal Stem Cells (MSCs) as Potential Vectors for Delivery of Therapeutic Agents to Breast Tumours. NBCRI/NCBES Breast Cancer Research Day.
RM Dwyer, FP Barry, T O'Brien and MJ Kerin. (2007) Mesenchymal Stem Cells (MSCs) as Potential Vectors for Delivery of Therapeutic Agents to Breast Tumours. NBCRI/NCBES Breast Cancer Research Day. Conference Paper [Details]
(2007) The role of Chemokine production by Primary Breast Cancer Stromal Cells in tumour progression.. Association of Surgeons of Great Britain and Ireland (ASGBI).
Shirley M Potter-Beirne, Roisin M Dwyer, Micheal J Kerin (2007) The role of Chemokine production by Primary Breast Cancer Stromal Cells in tumour progression.. Association of Surgeons of Great Britain and Ireland (ASGBI). Conference Paper [Details]
(2007) Investigation of the Potential of Human Mesenchymal Stem Cells (hMSC) as Vectors for Therapeutic Gene Delivery to Breast Tumours. Irish Society for Gene and Cell Therapy (ISGCT).
RM Dwyer, FP Barry, T O'Brien and MJ Kerin. (2007) Investigation of the Potential of Human Mesenchymal Stem Cells (hMSC) as Vectors for Therapeutic Gene Delivery to Breast Tumours. Irish Society for Gene and Cell Therapy (ISGCT). Conference Paper [Details]
(2008) The Role of Bone-Derived Mesenchymal Stem Cells (MSCs) in Facilitating Breast Cancer Metastasis. Sylvester O Halloran Surgical Symposium.
FT Martin, RM Dwyer, TP Griffin, JM Murphy, FP Barry, T O'Brien and MJ Kerin (2008) The Role of Bone-Derived Mesenchymal Stem Cells (MSCs) in Facilitating Breast Cancer Metastasis. Sylvester O Halloran Surgical Symposium. Conference Paper [Details]
(2008) Marrow-Derived Mesenchymal Stem Cells (MSCs) stimulate chemokine secretion and alter gene expression in breast cancer cells. Association of Surgeons of Great Britain and Ireland (ASGBI).
FT Martin, RM Dwyer, TP Griffin, JM Murphy, FP Barry, T O'Brien and MJ Kerin (2008) Marrow-Derived Mesenchymal Stem Cells (MSCs) stimulate chemokine secretion and alter gene expression in breast cancer cells. Association of Surgeons of Great Britain and Ireland (ASGBI). Conference Paper [Details]
(2009) Characterisation of primary tumour stromal cells and their role in the breast tumour microenvironment. Sir Peter Freyer Surgical Symposium.
M.C. Hartmann, R.M. Dwyer, S.M. Potter, M.P. Boyle and M.J. Kerin. (2009) Characterisation of primary tumour stromal cells and their role in the breast tumour microenvironment. Sir Peter Freyer Surgical Symposium. Conference Paper [Details]
(2009) Interactions between Mesenchymal Stem Cells (MSCs) and Breast Cancer Cells support induction of Epithelial - Mesenchymal Transition (EMT). Irish Association for Cancer Research (IACR).
FT Martin, RM Dwyer, J Kelly, JM Murphy, N Miller, E Hennessy, C Curran, FP Barry, T O'Brien, MJ Kerin (2009) Interactions between Mesenchymal Stem Cells (MSCs) and Breast Cancer Cells support induction of Epithelial - Mesenchymal Transition (EMT). Irish Association for Cancer Research (IACR). Conference Paper [Details]
(2009) Sodium iodide symporter (NIS) mediated tracking of mesenchymal stem cell (MSC) migration to breast tumours in vivo. European Society for Gene and Cell Therapy (ESGCT).
Dwyer R, Ryan J, Havelin R, Morris J, O'Flatharta C, Duffy G, Miller B, Liu ZL, Barrett H, Murphy M, Barry F, O'Brien T, Kerin M (2009) Sodium iodide symporter (NIS) mediated tracking of mesenchymal stem cell (MSC) migration to breast tumours in vivo. European Society for Gene and Cell Therapy (ESGCT). Conference Paper [Details]
(2009) Potential promotion of metastatis of circulating breast cancer cells through interactions with mesenchymal stem cells (MSCs). CANCER RESEARCH.
Martin, FT,Dwyer, RM,Murphy, MJ,Barry, FP,Brien, TO,Kerin, MJ (2009) Potential promotion of metastatis of circulating breast cancer cells through interactions with mesenchymal stem cells (MSCs). CANCER RESEARCH. Conference Paper [Details]
(2009) Potential role of Monocyte Chemotactic Protein-1 (MCP-1) in the Breast Cancer Microenvironment. Sylvester O Halloran Surgical Symposium.
M.C. Hartmann, R.M. Dwyer, M.P. Boyle, S.M. Potter and M.J. Kerin (2009) Potential role of Monocyte Chemotactic Protein-1 (MCP-1) in the Breast Cancer Microenvironment. Sylvester O Halloran Surgical Symposium. Conference Paper [Details]
(2009) TUMOUR PROMOTING ROLE OF PRIMARY STROMAL CELLS IN THE BREAST CANCER MICROENVIRONMENT IN VIVO AND IN VITRO. Irish Association for Cancer Research (IACR).
Shirley M Potter, Roisin M Dwyer, Marie P Boyle, Marion C Hartmann, Catherine E Curran, Emer Hennessy and Michael J Kerin. (2009) TUMOUR PROMOTING ROLE OF PRIMARY STROMAL CELLS IN THE BREAST CANCER MICROENVIRONMENT IN VIVO AND IN VITRO. Irish Association for Cancer Research (IACR). Conference Paper [Details]
(2009) Paracrine impact of Mesenchymal Stem Cells (MSCs) on breast cancer cell gene expression. Sylvester O Halloran Surgical Symposium.
John C Kelly, Roisin M. Dwyer, Fiachra T Martin, Mary Murphy, Frank P Barry, Timothy O'Brien and Michael J. Kerin (2009) Paracrine impact of Mesenchymal Stem Cells (MSCs) on breast cancer cell gene expression. Sylvester O Halloran Surgical Symposium. Conference Paper [Details]
(2009) Mesenchymal stem cells and breast cancer: therapeutic delivery vehicles or tumour promoting agents. Sir Peter Freyer Surgical Symposium.
John C Kelly, Roisin M. Dwyer, Mary Murphy, Frank P Barry, Timothy O'Brien and Michael J. Kerin (2009) Mesenchymal stem cells and breast cancer: therapeutic delivery vehicles or tumour promoting agents. Sir Peter Freyer Surgical Symposium. Conference Paper [Details]
(2009) Expression of the sodium iodide symporter in breast cancer. Sir Peter Freyer Surgical Symposium.
J. Ryan, E. Hennessey, C.C. Curran, J.C. Morris, M.J. Kerin and R.M. Dwyer (2009) Expression of the sodium iodide symporter in breast cancer. Sir Peter Freyer Surgical Symposium. Conference Paper [Details]
(2009) Mesenchymal Stem Cells (MSCs) may promote breast cancer metastatic potential through stimulation of Epithelial-Mesenchymal Transition (EMT). Society of Academic & Research Surgery (SARS).
FT Martin, RM Dwyer, JM Murphy, N Miller, FP Barry, T O'Brien and MJ Kerin (2009) Mesenchymal Stem Cells (MSCs) may promote breast cancer metastatic potential through stimulation of Epithelial-Mesenchymal Transition (EMT). Society of Academic & Research Surgery (SARS). Conference Paper [Details]
(2010) Investigation of potential role of CCL5 in breast cancer progression. Sylvester O Halloran Surgical Symposium.
Hartmann MC, Dwyer RM, Costello M, Kerin MJ (2010) Investigation of potential role of CCL5 in breast cancer progression. Sylvester O Halloran Surgical Symposium. Conference Paper [Details]
(2010) Correlation between circulating and tumour tissue CCL5 and TGFß1 in breast cancer patients. Sir Peter Freyer Surgical Symposium.
Hartmann MC, Dwyer RM, Costello M, Kerin MJ (2010) Correlation between circulating and tumour tissue CCL5 and TGFß1 in breast cancer patients. Sir Peter Freyer Surgical Symposium. Conference Paper [Details]
(2010) Potential of circulating chemokines as serum tumour markers in breast cancer. Society of Academic & Research Surgery (SARS).
Costello M, Hartmann MC, Dwyer RM, Kerin MJ (2010) Potential of circulating chemokines as serum tumour markers in breast cancer. Society of Academic & Research Surgery (SARS). Conference Paper [Details]
(2010) Breast Tumour Stromal-Epithelial Interactions Stimulate Increased VEGF Secretion And Angiogenesis In Vitro and In Vivo.. Sir Peter Freyer Surgical Symposium.
S Khan, RM Dwyer, SM Potter and MJ Kerin (2010) Breast Tumour Stromal-Epithelial Interactions Stimulate Increased VEGF Secretion And Angiogenesis In Vitro and In Vivo.. Sir Peter Freyer Surgical Symposium. Conference Paper [Details]
(2010) Potential role for thyroid hormones in regulation of mammary Sodium Iodide Symporter expression. Sir Peter Freyer Surgical Symposium.
J. Ryan, C.C. Curran, E. Hennessy, J.C. Morris, M.J. Kerin and R.M. Dwyer (2010) Potential role for thyroid hormones in regulation of mammary Sodium Iodide Symporter expression. Sir Peter Freyer Surgical Symposium. Conference Paper [Details]
(2011) Cellular Interactions in the Primary Tumour Microenvironment. Sir Peter Freyer Surgical Symposium.
Sonja Khan, Roisin M Dwyer, Karl J Sweeney and Michael J Kerin (2011) Cellular Interactions in the Primary Tumour Microenvironment. Sir Peter Freyer Surgical Symposium. Conference Paper [Details]

Conference Poster

  Year Publication
(2006) Mesenchymal stem cell-mediated stimulation of breast cancer cell migration. European Association for Cancer Research (EACR).
RM Dwyer, FP Barry, T O'Brien and MJ Kerin. (2006) Mesenchymal stem cell-mediated stimulation of breast cancer cell migration. European Association for Cancer Research (EACR). Conference Poster [Details]
(2007) Secretion and Expression of Monocyte Chemotactic Protein-1 (MCP-1) by Primary Breast Cancer Cell Populations.. Society of Academic & Research Surgery (SARS).
Shirley Potter Beirne, Roisin M Dwyer, Professor Micheal J Kerin (2007) Secretion and Expression of Monocyte Chemotactic Protein-1 (MCP-1) by Primary Breast Cancer Cell Populations.. Society of Academic & Research Surgery (SARS). Conference Poster [Details]
(2007) Bone Marrow-Derived Mesenchymal Stem Cells (MSCs) as potential interacting targets for circulating breast cancer cells. Irish Association for Cancer Research.
RM Dwyer, FP Barry, T O'Brien and MJ Kerin. (2007) Bone Marrow-Derived Mesenchymal Stem Cells (MSCs) as potential interacting targets for circulating breast cancer cells. Irish Association for Cancer Research. Conference Poster [Details]
(2007) The role of Chemokine production by Primary Breast Cancer Stromal Cells in tumour progression.. Irish Association for Cancer Research.
Shirley M Potter-Beirne, Roisin M Dwyer, Micheal J Kerin (2007) The role of Chemokine production by Primary Breast Cancer Stromal Cells in tumour progression.. Irish Association for Cancer Research. Conference Poster [Details]
(2007) Investigation of the potential of human Mesenchymal Stem Cells (hMSC) as vectors for therapeutic gene delivery to breast tumours. European Cancer Organisation (ECCO).
R.M. Dwyer, F.P. Barry, T. O'Brien, M.J. Kerin. (2007) Investigation of the potential of human Mesenchymal Stem Cells (hMSC) as vectors for therapeutic gene delivery to breast tumours. European Cancer Organisation (ECCO). Conference Poster [Details]
(2007) The potential role of bone derived cells in the development of breast cancer metastases. European Cancer Organisation (ECCO).
AP Molloy, RM Dwyer, MJ Kerin (2007) The potential role of bone derived cells in the development of breast cancer metastases. European Cancer Organisation (ECCO). Conference Poster [Details]
(2007) Distinct Chemokines Mediate Tumourigenicity of Breast Cancer Cells. San Antonio Breast Cancer Symposium.
Shirley Potter Beirne, Roisin Dwyer, and Michael Kerin. (2007) Distinct Chemokines Mediate Tumourigenicity of Breast Cancer Cells. San Antonio Breast Cancer Symposium. Conference Poster [Details]
(2007) Osteoblasts and their progenitors stimulate breast cancer cell migration through chemokine secretion. San Antonio Breast Cancer Symposium.
Molloy AP, Dwyer RM, Kerin MJ. (2007) Osteoblasts and their progenitors stimulate breast cancer cell migration through chemokine secretion. San Antonio Breast Cancer Symposium. Conference Poster [Details]
(2007) The Role of Primary Stromal Cell-derived Chemokines in the Breast Tumour Microenvironment. European Cancer Organisation (ECCO).
Shirley M Potter-Beirne, Roisin M Dwyer and Michael J Kerin (2007) The Role of Primary Stromal Cell-derived Chemokines in the Breast Tumour Microenvironment. European Cancer Organisation (ECCO). Conference Poster [Details]
(2007) Analysis of the role of osteogenic cells in breast cancer metastasis. Association of Surgeons of Great Britain and Ireland (ASGBI).
AP Molloy, RM Dwyer, MJ Kerin (2007) Analysis of the role of osteogenic cells in breast cancer metastasis. Association of Surgeons of Great Britain and Ireland (ASGBI). Conference Poster [Details]
(2007) Role of Osteoblasts in Promoting Breast Cancer Cell Migration and Proliferation. Irish Association for Cancer Research.
AP Molloy, RM Dwyer, MJ Kerin (2007) Role of Osteoblasts in Promoting Breast Cancer Cell Migration and Proliferation. Irish Association for Cancer Research. Conference Poster [Details]
(2008) Sodium Iodide Symporter (NIS) mediated Iodide Uptake in Mesenchymal Stem Cells following Adenoviral Transduction. Irish Society for Gene and Cell Therapy (ISGCT).
RM Dwyer, JC Morris, JM Murphy, FP Barry, T O'Brien and MJ Kerin. (2008) Sodium Iodide Symporter (NIS) mediated Iodide Uptake in Mesenchymal Stem Cells following Adenoviral Transduction. Irish Society for Gene and Cell Therapy (ISGCT). Conference Poster [Details]
(2008) Marrow-Derived Mesenchymal Stem Cells (MSCs) stimulate chemokine secretion and gene expression in breast cancer cells. European Association for Cancer Research (EACR).
FT Martin, RM Dwyer, TP Griffin, JM Murphy, FP Barry, T O'Brien and MJ Kerin (2008) Marrow-Derived Mesenchymal Stem Cells (MSCs) stimulate chemokine secretion and gene expression in breast cancer cells. European Association for Cancer Research (EACR). Conference Poster [Details]
(2008) Investigation of the potential of Mesenchymal Stem Cells (MSCs) for gene delivery to breast tumours. European Association for Cancer Research (EACR).
RM Dwyer, JC Morris, JM Murphy, FP Barry, T O'Brien and MJ Kerin. (2008) Investigation of the potential of Mesenchymal Stem Cells (MSCs) for gene delivery to breast tumours. European Association for Cancer Research (EACR). Conference Poster [Details]
(2008) Circulating Stromal Cell Derived Factor-1a (SDF-1a) in Premenopausal Women is Influenced by Phase of Menstrual Cycle. Sir Peter Freyer Surgical Symposium.
Shirley M. Potter, Roisin M. Dwyer, Emer Hennessy, Damian G. Griffin and Michael J. Kerin. (2008) Circulating Stromal Cell Derived Factor-1a (SDF-1a) in Premenopausal Women is Influenced by Phase of Menstrual Cycle. Sir Peter Freyer Surgical Symposium. Conference Poster [Details]
(2008) Circulating Stromal Cell Derived Factor-1a (SDF-1a) in Premenopausal Women is Influenced by Phase of Menstrual Cycle. Association of Surgeons of Great Britain and Ireland (ASGBI).
Shirley M. Potter, Roisin M. Dwyer, Emer Hennessy, Damien Griffin and Michael J. Kerin. (2008) Circulating Stromal Cell Derived Factor-1a (SDF-1a) in Premenopausal Women is Influenced by Phase of Menstrual Cycle. Association of Surgeons of Great Britain and Ireland (ASGBI). Conference Poster [Details]
(2008) Next Generation Mesenchymal Stem Cells for Regenerative Medicine Applications: Antibodies, Peptides and Lipoplexes for isolation, expansion and genetic modification of MSCs from several species. Irish Society for Gene and Cell Therapy (ISGCT).
Udo Greiser, Melissa Hoare, Tyrone Bowes, Roisin Dwyer, Daniel O'Toole, Kaveh Mashayekhi, Mary Murphy, Frank Barry and Timothy O'Brien (2008) Next Generation Mesenchymal Stem Cells for Regenerative Medicine Applications: Antibodies, Peptides and Lipoplexes for isolation, expansion and genetic modification of MSCs from several species. Irish Society for Gene and Cell Therapy (ISGCT). Conference Poster [Details]
(2008) Sodium Iodide Symporter (NIS) mediated Iodide Uptake in Mesenchymal Stem Cells following Adenoviral Transduction. American Society of Gene Therapy (ASGT).
RM Dwyer, JC Morris, JM Murphy, FP Barry, T O'Brien and MJ Kerin. (2008) Sodium Iodide Symporter (NIS) mediated Iodide Uptake in Mesenchymal Stem Cells following Adenoviral Transduction. American Society of Gene Therapy (ASGT). Conference Poster [Details]
(2008) Hormonal regulation of breast cancer associated chemokines. European Association for Cancer Research (EACR).
Shirley M. Potter, Roisin M. Dwyer, Emer Hennessy, Damien Griffin and Michael J. Kerin. (2008) Hormonal regulation of breast cancer associated chemokines. European Association for Cancer Research (EACR). Conference Poster [Details]
(2008) Potential promotion of the metastatic potential of circulating Breast Cancer Cells through interactions with Mesenchymal Stem Cells (MSCs). San Antonio Breast Cancer Symposium.
FT Martin, RM Dwyer, JM Murphy, FP Barry, T O'Brien and MJ Kerin (2008) Potential promotion of the metastatic potential of circulating Breast Cancer Cells through interactions with Mesenchymal Stem Cells (MSCs). San Antonio Breast Cancer Symposium. Conference Poster [Details]
(2008) Stromal-epithalial cell Cross-talk In The Breast Tumour Microenvironment Elicits Changes In Gene Expression in Breast Cancer Epithelial Cells. San Antonio Breast Cancer Symposium.
Shirley M Potter, Roisin M Dwyer, Michael J Kerin (2008) Stromal-epithalial cell Cross-talk In The Breast Tumour Microenvironment Elicits Changes In Gene Expression in Breast Cancer Epithelial Cells. San Antonio Breast Cancer Symposium. Conference Poster [Details]
(2009) DISTINCT PROPERTIES OF BREAST TUMOUR COMPARED TO NORMAL STROMAL CELLS AND THEIR INFLUENCE ON BREAST CANCER EPITHELIAL CELL GENE EXPRESSION. Society of Academic & Research Surgery (SARS).
Shirley M Potter, Marie P Boyle, Roisin M Dwyer, Nicola Miller and Micheal J Kerin. (2009) DISTINCT PROPERTIES OF BREAST TUMOUR COMPARED TO NORMAL STROMAL CELLS AND THEIR INFLUENCE ON BREAST CANCER EPITHELIAL CELL GENE EXPRESSION. Society of Academic & Research Surgery (SARS). Conference Poster [Details]
(2009) Characterization of primary tumour stromal cells and their potential role in the breast cancer microenvironment. European Cancer Organisation (ECCO)/ESMO.
M.C. Hartmann, R.M. Dwyer, S.M. Potter, P Dockery and M.J. Kerin. (2009) Characterization of primary tumour stromal cells and their potential role in the breast cancer microenvironment. European Cancer Organisation (ECCO)/ESMO. Conference Poster [Details]
(2009) Mesenchymal Stem Cell (MSC) secretion of TGFb and VEGF stimulates Epithelial to Mesenchymal Transition (EMT) in breast cancer cell lines. European Cancer Organisation (ECCO)/ESMO.
John C Kelly, Roisin M. Dwyer, Mary Murphy, Frank P Barry, Timothy O'Brien and Michael J. Kerin (2009) Mesenchymal Stem Cell (MSC) secretion of TGFb and VEGF stimulates Epithelial to Mesenchymal Transition (EMT) in breast cancer cell lines. European Cancer Organisation (ECCO)/ESMO. Conference Poster [Details]
(2009) Correlation of Sodium Iodide Symporter (NIS) and Retinoic Acid Receptor Alpha (RARA) expression in breast cancer. European Cancer Organisation (ECCO)/ESMO.
J. Ryan, E. Hennessy, C.C. Curran, J.C. Morris, M.J. Kerin and R.M. Dwyer (2009) Correlation of Sodium Iodide Symporter (NIS) and Retinoic Acid Receptor Alpha (RARA) expression in breast cancer. European Cancer Organisation (ECCO)/ESMO. Conference Poster [Details]
(2009) Role of Stromal-Epithelial interactions in the primary breast tumour microenvironment in vitro and in vivo. American Association for Cancer Research (AACR).
Shirley M Potter, Roisin M Dwyer, Marie P Boyle, Marion C Hartmann, Catherine E Curran, Emer Hennessy and Michael J Kerin. (2009) Role of Stromal-Epithelial interactions in the primary breast tumour microenvironment in vitro and in vivo. American Association for Cancer Research (AACR). Conference Poster [Details]
(2009) Analysis of primary breast tumour stromal cells and their potential role in disease progression. San Antonio Breast Cancer Symposium.
M.C. Hartmann, R.M. Dwyer and M.J. Kerin (2009) Analysis of primary breast tumour stromal cells and their potential role in disease progression. San Antonio Breast Cancer Symposium. Conference Poster [Details]
(2009) Potential Role of Mesenchymal Stem Cells (MSCs) in the Breast Tumour Microenvironment: Stimulation of Epithelial to Mesenchymal Transition (EMT). American Association for Cancer Research (AACR).
FT Martin, RM Dwyer, JM Murphy, N Miller, FP Barry, T O'Brien and MJ Kerin (2009) Potential Role of Mesenchymal Stem Cells (MSCs) in the Breast Tumour Microenvironment: Stimulation of Epithelial to Mesenchymal Transition (EMT). American Association for Cancer Research (AACR). Conference Poster [Details]
(2009) Effect of Monocyte Chemotactic Protein-1 (MCP-1) on breast cancer cell proliferation and gene expression. Targeted AntiCancer Therapies (TAT), , 23rd-25th March 2009.
Marion C Hartmann, Roisin M Dwyer, Marie P Boyle, Shirley M Potter and Prof Michael J Kerin (2009) Effect of Monocyte Chemotactic Protein-1 (MCP-1) on breast cancer cell proliferation and gene expression. Targeted AntiCancer Therapies (TAT), , 23rd-25th March 2009. Conference Poster [Details]
(2010) CCL5 in Breast Cancer: Circulating systemic levels and gene expression in the primary tumour microenvironment. American Association for Cancer Research (AACR).
Hartmann MC, Dwyer RM, Costello M, Kerin MJ (2010) CCL5 in Breast Cancer: Circulating systemic levels and gene expression in the primary tumour microenvironment. American Association for Cancer Research (AACR). Conference Poster [Details]
(2010) Circulating and tumour tissue levels of CCL5/RANTES in breast cancer. Irish Association for Cancer Research (IACR).
Hartmann MC, Dwyer RM, Costello M, Kerin MJ (2010) Circulating and tumour tissue levels of CCL5/RANTES in breast cancer. Irish Association for Cancer Research (IACR). Conference Poster [Details]
(2010) Expression of the Sodium Iodide Symporter and potential regulators in Normal, Benign and Malignant breast tissue. Irish Association for Cancer Research (IACR).
J. Ryan, C.C. Curran, E. Hennessy, J.C. Morris, M.J. Kerin and R.M. Dwyer (2010) Expression of the Sodium Iodide Symporter and potential regulators in Normal, Benign and Malignant breast tissue. Irish Association for Cancer Research (IACR). Conference Poster [Details]
(2010) Potential Role of Primary Breast Cancer Stromal Cells in the Development of Endocrine Resistance. Irish Association for Cancer Research (IACR).
S Khan, RM Dwyer, MC Hartmann and MJ Kerin (2010) Potential Role of Primary Breast Cancer Stromal Cells in the Development of Endocrine Resistance. Irish Association for Cancer Research (IACR). Conference Poster [Details]
(2011) Mesenchymal Stem Cell (MSC) mediated delivery of the Sodium Iodide Symporter (NIS) supports radionuclide imaging and treatment of breast cancer. American Association for Cancer Research (AACR).
Roisin M. Dwyer, James Ryan, Ronan Havelin, John C. Morris, Cathal O'Flatharta, Brian Miller, Zhonglin Liu, Mark Foley, Harrison H. Barrett, Mary Murphy, Frank P. Barry, Timothy O'Brien and Michael J. Kerin. (2011) Mesenchymal Stem Cell (MSC) mediated delivery of the Sodium Iodide Symporter (NIS) supports radionuclide imaging and treatment of breast cancer. American Association for Cancer Research (AACR). Conference Poster [Details]

Editorial

  Year Publication
(2002) The sodium iodide symporter and thyroid disease.
Smyth, PPA,Dwyer, RM (2002) The sodium iodide symporter and thyroid disease. Editorial [Details]

Meeting

  Year Publication
(2007) The role of primary stromal cell-derived chemokines in the breast tumour microenvironment.
Potter, SM,Dwyer, RM,Kerin, MJ (2007) The role of primary stromal cell-derived chemokines in the breast tumour microenvironment. Meeting [Details]
(2007) The role of primary stromal cell-derived chemokines in the breast tumour microenvironment.
Potter-Beirne, S,Dwyer, R,Kerin, MJ (2007) The role of primary stromal cell-derived chemokines in the breast tumour microenvironment. Meeting [Details]
(2008) Next generation mesenchymal stem cells for regenerative medicine applications: antibodies, peptides and lipoplexes for isolation, expansion and genetic modification of mscs.
Greiser, U,Hoare, M,Bowes, T,Dwyer, R,O'Toole, D,Mashayekhi, K,Murphy, M,O'Brien, T,Barry, F (2008) Next generation mesenchymal stem cells for regenerative medicine applications: antibodies, peptides and lipoplexes for isolation, expansion and genetic modification of mscs. Meeting [Details]
(2009) Sodium iodide symporter (NIS) mediated tracking of mesenchymal stem cell (MSC) migration to breast tumours in vivo.
Dwyer, R,Ryan, J,Havelin, R,Morris, J,O'Flatharta, C,Duffy, G,Miller, B,Liu, ZL,Barrett, H,Murphy, M,Barry, F,O'Brien, T,Kerin, M (2009) Sodium iodide symporter (NIS) mediated tracking of mesenchymal stem cell (MSC) migration to breast tumours in vivo. Meeting [Details]
(2010) BREAST TUMOUR STROMAL-EPITHELIAL INTERACTIONS STIMULATE INCREASED VEGF SECRETION AND ANGIOGENESIS IN VITRO AND IN VIVO.
Khan, S,Dwyer, RM,Potter, SM,Kerin, MJ (2010) BREAST TUMOUR STROMAL-EPITHELIAL INTERACTIONS STIMULATE INCREASED VEGF SECRETION AND ANGIOGENESIS IN VITRO AND IN VIVO. Meeting [Details]
(2010) DIGIT RATIO (2D:4D) AS A PREDICTOR OF BREAST CANCER PREDISPOSITION.
Devine, A,Kelly, J,Heneghan, H,Dwyer, R,Kerin, M (2010) DIGIT RATIO (2D:4D) AS A PREDICTOR OF BREAST CANCER PREDISPOSITION. Meeting [Details]
(2010) INVESTIGATION OF POTENTIAL ROLE OF CCL5 IN BREAST CANCER PROGRESSION.
Hartmann, MC,Dwyer, RM,Costello, M,Kerin, MJ (2010) INVESTIGATION OF POTENTIAL ROLE OF CCL5 IN BREAST CANCER PROGRESSION. Meeting [Details]
(2010) Potential of circulating chemokines as serum tumour markers in breast cancer.
Costello, M,Hartmann, M,Dwyer, R,Kerin, M (2010) Potential of circulating chemokines as serum tumour markers in breast cancer. Meeting [Details]
(2010) POTENTIAL ROLE FOR THYROID HORMONES IN REGULATION OF MAMMARY NIS EXPRESSION.
Ryan, J,Hennessy, E,Curran, CC,Morris, JC,Kerin, MJ,Dwyer, RM (2010) POTENTIAL ROLE FOR THYROID HORMONES IN REGULATION OF MAMMARY NIS EXPRESSION. Meeting [Details]
(2011) Cellular interactions in the primary tumour microenvironment.
Khan, S,Dwyer, RM,Sweeney, KJ,Kerin, MJ (2011) Cellular interactions in the primary tumour microenvironment. Meeting [Details]
(2011) TGF-beta 1 mediated stimulation of VEGF secretion by breast cancer cells.
Costello, M,Dwyer, RM,Ryan, J,Hartmann, M,Kerin, MJ (2011) TGF-beta 1 mediated stimulation of VEGF secretion by breast cancer cells. Meeting [Details]
(2012) Mesenchymal stem cells (MSCs) and colorectal cancer.
Hogan, NM,Dwyer, RM,Joyce, MR,Kerin, MJ (2012) Mesenchymal stem cells (MSCs) and colorectal cancer. Meeting [Details]
(2012) Plasminogen activator inhibitor-1 (PAI-1) secretion by mesenchymal stem cells and colorectal cancer cells in 3-dimensional culture.
Hogan, NM,Dwyer, RM,Joyce, MR,Kerin, MJ (2012) Plasminogen activator inhibitor-1 (PAI-1) secretion by mesenchymal stem cells and colorectal cancer cells in 3-dimensional culture. Meeting [Details]
(2012) Analysis of miR10b expression during disease progression in a murine model of breast cancer.
Waters, PS,Dwyer, RM,Kerin, MJ (2012) Analysis of miR10b expression during disease progression in a murine model of breast cancer. Meeting [Details]
(2012) Relationship Between Circulating and Tissue MiRNAs in a Murine Model of Breast Cancer.
Waters, PS,Dwyer, RM,Wall, D,McDermott, AM,Newell, J,Kerin, MJ (2012) Relationship Between Circulating and Tissue MiRNAs in a Murine Model of Breast Cancer. Meeting [Details]
(2012) Evaluation of MicroRNA Secretion From Cancer Cells in Vitro.
Glynn, CL,Dwyer, RM,Khan, SJ,Kerin, MJ (2012) Evaluation of MicroRNA Secretion From Cancer Cells in Vitro. Meeting [Details]
(2012) Active Secretion of MicroRNAs and Plasminogen Activator Inhibitor-1 (PAI-1) by Colorectal Cancer Cells and Associated Stroma In Vitro.
Hogan, NM,Dwyer, RM,Glynn, CL,Joyce, MR,Kerin, MJ (2012) Active Secretion of MicroRNAs and Plasminogen Activator Inhibitor-1 (PAI-1) by Colorectal Cancer Cells and Associated Stroma In Vitro. Meeting [Details]
(2012) Active Secretion of MicroRNAs by Breast Cancer Cells.
Glynn, CL,Dwyer, RM,Khan, S,Kerin, MJ (2012) Active Secretion of MicroRNAs by Breast Cancer Cells. Meeting [Details]
(2013) Analysis of mir-339-5p expression and function in breast cancer.
Khan, S,Brougham, C,Wall, D,Curran, C,Newel, J,Kerin, MJ,Dwyer, RM (2013) Analysis of mir-339-5p expression and function in breast cancer. Meeting [Details]
(2013) Relationship between circulating miRNAs and breast cancer epithelial subtype.
Duignan, MF,Brougham, C,Waters, PS,Dwyer, RM,Kerin, MJ (2013) Relationship between circulating miRNAs and breast cancer epithelial subtype. Meeting [Details]
(2013) Identification and validation of a microrna signature associated with breast cancer progression.
Waters, PS,Dwyer, RM,Hyland, P,Brougham, C,Wall, D,Kerin, MJ (2013) Identification and validation of a microrna signature associated with breast cancer progression. Meeting [Details]
(2013) Interactions between mesenchymal stem cells (MSCs) and colorectal cancer cells are mediated by plasminogen activator inhibitor type 1 (PAI-1).
Hogan, NM,Dwyer, RM,Joyce, MR,Kerin, MJ (2013) Interactions between mesenchymal stem cells (MSCs) and colorectal cancer cells are mediated by plasminogen activator inhibitor type 1 (PAI-1). Meeting [Details]
(2013) Relationship between MicroRNA-379 and Cyclin-B1 in breast cancer.
O'Neill, GJ,Khan, S,Sahrudin, A,Kerin, M,Dwyer, R (2013) Relationship between MicroRNA-379 and Cyclin-B1 in breast cancer. Meeting [Details]
(2013) Mesenchymal stem cell secreted PAI-1 impacts on colon cancer cell migration and proliferation.
Hogan, NM,Dwyer, RM,Joyce, MR,Kerin, MJ (2013) Mesenchymal stem cell secreted PAI-1 impacts on colon cancer cell migration and proliferation. Meeting [Details]
(2013) Impact of tumour epithelial subtype on circulating microRNAs in breast cancer.
Brougham, CL,Waters, PS,Wall, D,Kerin, MJ,Dwyer, RM (2013) Impact of tumour epithelial subtype on circulating microRNAs in breast cancer. Meeting [Details]
(2013) Relationship between Circulating Micrornas and Breast Cancer Intrinsic Subtype.
Brougham, CL,Waters, PS,Wall, D,Dwyer, RM,Kerin, MJ (2013) Relationship between Circulating Micrornas and Breast Cancer Intrinsic Subtype. Meeting [Details]
(2013) Mir-339-5p Acts as A Tumour Suppressor in Breast Cancer, Mediated at Least in Part Through Regulation of Cell Proliferation.
Khan, S,Brougham, CL,Wall, D,Newell, J,Kerin, MJ,Dwyer, RM (2013) Mir-339-5p Acts as A Tumour Suppressor in Breast Cancer, Mediated at Least in Part Through Regulation of Cell Proliferation. Meeting [Details]
(2013) Role of Mesenchymal Stem Cells in the colorectal cancer cell environment: stimulation of Epithelial-Mesenchymal Transition.
Hogan, NM,Joyce, MR,Dwyer, RM,Kerin, MJ (2013) Role of Mesenchymal Stem Cells in the colorectal cancer cell environment: stimulation of Epithelial-Mesenchymal Transition. Meeting [Details]
(2013) Circulating and Tissue Levels of miR-504 in colorectal and breast cancer.
Hogan, N,Khan, S,Huong, QTT,Brogham, C,Joyce, MR,Kerin, MJ,Dwyer, RM (2013) Circulating and Tissue Levels of miR-504 in colorectal and breast cancer. Meeting [Details]
(2013) Elevated expression of miR-106 and miR-202 in breast cancer.
McLoughlin, M,Glynn, CL,Waters, PS,Khan, S,Dwyer, RM,Kerin, MJ (2013) Elevated expression of miR-106 and miR-202 in breast cancer. Meeting [Details]

Reviews

  Year Publication
(2010) Advances in mesenchymal stem cell-mediated gene therapy for cancer. Stem Cell Res Ther.
Dwyer RM, Khan S, Barry FP, O'Brien T, Kerin MJ (2010) Advances in mesenchymal stem cell-mediated gene therapy for cancer. Stem Cell Res Ther. Reviews [Details]
(2010) Mesenchymal Stem Cells and Cancer: Tumor-Specific Delivery Vehicles or Therapeutic Targets?.
Dwyer, RM,Kerin, MJ (2010) Mesenchymal Stem Cells and Cancer: Tumor-Specific Delivery Vehicles or Therapeutic Targets?. Reviews [DOI] [Details]

Workshops

  Year Publication
(2006) Breast Cancer Cells Migrate in Response to Bone Marrow-Derived Mesenchymal Stem Cells (MSCs). Sir Peter Freyer Surgical Symposium.
RM Dwyer, FP Barry, T O'Brien and MJ Kerin. (2006) Breast Cancer Cells Migrate in Response to Bone Marrow-Derived Mesenchymal Stem Cells (MSCs). Sir Peter Freyer Surgical Symposium. Workshops [Details]
(2007) Novel Chemokines Induce Migration of Breast Cancer Cells Towards Bone Marrow-Derived Mesenchymal Stem Cells. Society of Academic & Research Surgery (SARS).
RM Dwyer, FP Barry, T O'Brien and MJ Kerin. (2007) Novel Chemokines Induce Migration of Breast Cancer Cells Towards Bone Marrow-Derived Mesenchymal Stem Cells. Society of Academic & Research Surgery (SARS). Workshops [Details]
(2007) The Role Of Primarry Stromal Cell-Derived Chemokines In The Breast Tumour Microenvironment. Nottingham International Breast Cancer Conference.
Dwyer, R. (2007) The Role Of Primarry Stromal Cell-Derived Chemokines In The Breast Tumour Microenvironment. Nottingham International Breast Cancer Conference. Workshops [Details]
(2007) Distinct Chemokines Mediate Tumourigenicity Of Breast Cancer Cells. Sir Peter Freyer Surgical Symposium.
Shirley Potter, Roisin Dwyer, and Michael Kerin. (2007) Distinct Chemokines Mediate Tumourigenicity Of Breast Cancer Cells. Sir Peter Freyer Surgical Symposium. Workshops [Details]
(2008) Role of Monocyte Chemotactic Protein-1 (MCP-1) in the Primary Breast Tumour Microenvironment. Sir Peter Freyer Surgical Symposium.
Shirley M Potter, Roisin M Dwyer, Michael J Kerin (2008) Role of Monocyte Chemotactic Protein-1 (MCP-1) in the Primary Breast Tumour Microenvironment. Sir Peter Freyer Surgical Symposium. Workshops [Details]
(2008) Mesenchymal Stem Cells modify chemokine secretion and gene expression in Breast Cancer Cells. Sir Peter Freyer Surgical Symposium.
FT Martin, RM Dwyer, JM Murphy, FP Barry, T O'Brien and MJ Kerin (2008) Mesenchymal Stem Cells modify chemokine secretion and gene expression in Breast Cancer Cells. Sir Peter Freyer Surgical Symposium. Workshops [Details]
(2008) Elevated Plasma SDF-1 alpha Correlates with Tumour Grade. Society of Academic & Research Surgery (SARS).
Shirley Potter Beirne, Roisin Dwyer, Kate Harrington and Michael Kerin. (2008) Elevated Plasma SDF-1 alpha Correlates with Tumour Grade. Society of Academic & Research Surgery (SARS). Workshops [Details]

Honours and Awards

  Year Title Awarding Body
2013 BREAST-PREDICT Collaborative Cancer Research Centre Irish Cancer society
2012 Irish Cancer Society Researcher of the Year Award Irish Cancer Society
2008 Research Project Grant Irish Cancer Society
2007 Research Project Grant Health Research Board
2005 National University of Ireland Postdoctroal Fellowship in the Sciences NUI

Internal Collaborators

  Name Description of Collaboration
Professor Timothy O'Brien

External Collaborators

  Name Organisation / Institute Country Description of Collaboration
Professor John Morris Mayo Clinic, Rochester, Minnesota U.S.A.