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Medicine

Dr Róisín Dwyer

BSc, MSc, PhD

Contact Details

Lecturer In Translational Science
Surgery
Office 2.15
2nd Floor
Lambe Institute for Translational Research
NUI Galway

T: +353 (0)91 493008
F: +353 (0)91 494509
E: roisin.dwyer@nuigalway.ie
 
researcher

Biography

Róisín Dwyer is a Lecturer in Translational Science in the Discipline of Surgery at NUI Galway. Following graduation from UCD with a degree in Science, Róisín went on to complete an MSc in Biological Sciences at DCU, and then was awarded her PhD in Medicine and Therapeutics from UCD. Róisín's research background in breast cancer led to a 3 year postdoctoral research position at the Mayo Clinic, Rochester, Minnesota. Upon her return to Ireland, she was awarded a National University of Ireland (NUI) Postdoctoral Fellowship in the Sciences, and joined the research team of Professor Michael Kerin in the National Breast Cancer Research Institute (NBCRI) at NUI Galway. She received Health Research Board funding in 2007, and a subsequent Project Grant awarded by the Irish Cancer Society in 2008. She was named Irish Cancer Society "Researcher of the Year" in 2012. Róisín's current research, in collaboration with both national and international research groups, focuses on novel approaches to breast cancer therapy. Her work investigates the potential of adult stem cells as vehicles for targeted delivery of therapeutic agents to breast tumours, with a specific interest in imaging modalities to track their migration in vivo. Other areas of interest include cellular interactions in the breast tumour microenvironment mediated by cytokines and microRNAs.

Research Interests

Research Projects

  Project Start Date End Date
IRC POSTGRADUATE SCHOLARSHIP 2016 KATIE GILLIGAN - Mesenchymal Stem Cell-mediated delivery of exosome-encapsulated microRNAs for the treatment of breast cancer 01-OCT-16 30-SEP-19
MESENCHYMAL ROISIN DWYER CRIO7DWY 01-APR-08 30-SEP-11

Book Chapters

  Year Publication
(2017) 'Circulating MicroRNAs in Cancer'
O'Brien KP, Ramphul E, Howard L, Gallagher WM, Malone C, Kerin MJ, Dwyer RM. (2017) 'Circulating MicroRNAs in Cancer' In: MicroRNA Profiling. New York: Springer. [DOI] [Details]
(2013) 'Diagnostic and Therapeutic Mesenchymal stem cells for breast cancer treatment'
Dwyer RM (2013) 'Diagnostic and Therapeutic Mesenchymal stem cells for breast cancer treatment' In: Stem Cell based Therapeutics for Cancer. Hoboken, NJ: John Wiley & Sons. [DOI] [Details]

Peer Reviewed Journals

  Year Publication
(2017) 'Engineering Exosomes for Cancer Therapy'
Gilligan KE, Dwyer RM. (2017) 'Engineering Exosomes for Cancer Therapy'. International Journal Of Molecular Sciences, 18 (6) [DOI] [Details]
(2017) 'Investigation on the effect of dehydration on tissue dielectric properties in the ex-vivo measurements'
Shahzad, S; Khan,S; Jones, M; Dwyer, RM; O’Halloran, M (2017) 'Investigation on the effect of dehydration on tissue dielectric properties in the ex-vivo measurements'. Biomedical Physics & Engineering Express, [Details]
(2017) 'S100 beta as a serum marker in endocrine resistant breast cancer'
Charmsaz, S;Hughes, E;Bane, FT;Tibbitts, P;McIlroy, M;Byrne, C;Cocchiglia, S;McBryan, J;Hennessy, BT;Dwyer, RM;Kerin, MJ;Hill, AD;Young, LS (2017) 'S100 beta as a serum marker in endocrine resistant breast cancer'. BMC medicine, 15 [DOI] [Details]
(2017) 'Dual plasmonic gold nanostars for photoacoustic imaging and photothermal therapy'
Raghavan, V,O'Flatharta, C,Dwyer, R,Breathnach, A,Zafar, H,Dockery, P,Wheatley, A,Keogh, I,Leahy, M,Olivo, M (2017) 'Dual plasmonic gold nanostars for photoacoustic imaging and photothermal therapy'. Nanomedicine, 12 :457-471 [DOI] [Details]
(2017) 'Rapid Microarray Based Sandwich Assay for the Direct Detection of microRNAs'
Clancy E, Burke M, Arabkari V, Barry T, Kelly H, Dwyer RM, Kerin MJ. and Smith TJ (2017) 'Rapid Microarray Based Sandwich Assay for the Direct Detection of microRNAs'. Analytical And Bioanalytical Chemistry, [Details]
(2016) 'Screening of exosomal microRNAs from colorectal cancer cells'
Clancy, C,Khan, S,Glynn, CL,Holian, E,Dockery, P,Lalor, P,Brown, JAL,Joyce, MR,Kerin, MJ,Dwyer, RM (2016) 'Screening of exosomal microRNAs from colorectal cancer cells'. Cancer Biomarkers, 17 :427-435 [DOI] [Details]
(2016) 'Exosome-encapsulated microRNAs as circulating biomarkers for breast cancer'
Joyce DP;Kerin MJ;Dwyer RM; (2016) 'Exosome-encapsulated microRNAs as circulating biomarkers for breast cancer'. International Journal Of Cancer, 139 (7) [DOI] [Details]
(2015) 'Cross Platform Standardisation of an Experimental Pipeline for Use in the Identification of Dysregulated Human Circulating MiRNAs'
Kelly, H,Downing, T,Tuite, NL,Smith, TJ,Kerin, MJ,Dwyer, RM,Clancy, E,Barry, T,Reddington, K (2015) 'Cross Platform Standardisation of an Experimental Pipeline for Use in the Identification of Dysregulated Human Circulating MiRNAs'. Plos One, 10 [DOI] [Details]
(2015) 'MicroRNA-10a is reduced in breast cancer and regulated in part through retinoic acid'
Khan, S,Wall, D,Curran, C,Newell, J,Kerin, MJ,Dwyer, RM (2015) 'MicroRNA-10a is reduced in breast cancer and regulated in part through retinoic acid'. BMC Cancer, 15 [DOI] [Details]
(2015) 'Solvent-selective routing for centrifugally automated solid-phase purification of RNA'
Dimov, N., Clancy, E., Gaughran, J., Boyle, D, McAuley, D., Glynn, M.T., Dwyer, R., Coughlan, H., Barry, T., Barrett, L.M., Smith, T.J. and Ducree, J. (2015) 'Solvent-selective routing for centrifugally automated solid-phase purification of RNA'. Microfluidics And Nanofluidics, 18 (5):859-871 [DOI] [ARAN Link] [Details]
(2014) 'Impact of Tumour Epithelial Subtype on Circulating microRNAs in Breast Cancer Patients'
Waters PS, Dwyer RM, Brougham C, Glynn CL, Wall D, Hyland P, Duignan M, McLoughlin M, Newell J, Kerin MJ (2014) 'Impact of Tumour Epithelial Subtype on Circulating microRNAs in Breast Cancer Patients'. Plos One, 9 (3) [DOI] [Details]
(2013) 'Objective assessment of image quality VI: imaging in radiation therapy'
Barrett, HH,Kupinski, MA,Mueller, S,Halpern, HJ,Morris, JC,Dwyer, R (2013) 'Objective assessment of image quality VI: imaging in radiation therapy'. Physics In Medicine And Biology, 58 :8197-8213 [DOI] [Details]
(2013) 'miR-379 Regulates Cyclin B1 Expression and Is Decreased in Breast Cancer'
Khan, S,Brougham, CL,Ryan, J,Sahrudin, A,O'Neill, G,Wall, D,Curran, C,Newell, J,Kerin, MJ,Dwyer, RM (2013) 'miR-379 Regulates Cyclin B1 Expression and Is Decreased in Breast Cancer'. Plos One, 8 [DOI] [Details]
(2013) 'Design and performance of a small-animal imaging system using synthetic collimation'
Havelin RJ, Miller BW, Barrett HH, Furenlid LR, Murphy JM, Dwyer RM, Foley MJ (2013) 'Design and performance of a small-animal imaging system using synthetic collimation'. Physics In Medicine And Biology, 58 (10):3397-3412 [DOI] [ARAN Link] [Details]
(2013) 'Impact of Mesenchymal Stem Cell Secreted PAI-1 on Colon Cancer Cell Migration and Proliferation'
Hogan NM, Joyce MR, Murphy JM, Barry FP, O'Brien T, Kerin MJ, Dwyer RM (2013) 'Impact of Mesenchymal Stem Cell Secreted PAI-1 on Colon Cancer Cell Migration and Proliferation'. Biochem Biophy Res Commun, [DOI] [Details]
(2012) 'Influence of stromal-epithelial interactions on breast cancer in vitro and in vivo'
Potter, SM,Dwyer, RM,Hartmann, MC,Khan, S,Boyle, MP,Curran, CE,Kerin, MJ (2012) 'Influence of stromal-epithelial interactions on breast cancer in vitro and in vivo'. Breast Cancer Research And Treatment, 131 :401-411 [DOI] [Details]
(2012) 'Mesenchymal stem cells in the colorectal tumor microenvironment: Recent progress and implications'
Hogan, NM,Dwyer, RM,Joyce, MR,Kerin, MJ (2012) 'Mesenchymal stem cells in the colorectal tumor microenvironment: Recent progress and implications'. International Journal Of Cancer, 131 (1):1-7 [DOI] [Details]
(2012) 'Isolation of secreted microRNAs (miRNAs) from cell-conditioned media'
Glynn C, Khan S, Kerin MJ and Dwyer RM. (2012) 'Isolation of secreted microRNAs (miRNAs) from cell-conditioned media'. MicroRNA, [ARAN Link] [Details]
(2012) 'Relationship between Circulating and Tissue microRNAs in a Murine Model of Breast Cancer'
Waters, PS,McDermott, AM,Wall, D,Heneghan, HM,Miller, N,Newell, J,Kerin, MJ,Dwyer, RM (2012) 'Relationship between Circulating and Tissue microRNAs in a Murine Model of Breast Cancer'. Plos One, 7 [DOI] [Details]
(2011) 'Relationship between CCL5 and transforming growth factor-β1 (TGFβ1) in breast cancer'
Hartmann MC, Dwyer RM, Costello M, Potter SM, Curran C, Hennessy E, Newell J, Griffin DG, Kerin MJ (2011) 'Relationship between CCL5 and transforming growth factor-β1 (TGFβ1) in breast cancer'. European Journal Of Cancer, 47 (11):1669-1675 [DOI] [Details]
(2011) 'The sodium iodide symporter (NIS) and potential regulators in normal, benign and malignant human breast tissue'
Ryan J, Curran CE, Hennessy E, Newell J, Morris JC, Kerin MJ, Dwyer RM. (2011) 'The sodium iodide symporter (NIS) and potential regulators in normal, benign and malignant human breast tissue'. Plos One, 6 (1) [Details]
(2011) 'Mesenchymal Stem Cell-mediated delivery of the sodium iodide symporter supports radionuclide imaging and treatment of breast cancer'
Dwyer RM;Ryan J;Havelin RJ;Morris JC;Miller BW;Liu Z;Flavin R;O'Flatharta C;Foley MJ;Barrett HH;Murphy JM;Barry FP;O'Brien T;Kerin MJ; (2011) 'Mesenchymal Stem Cell-mediated delivery of the sodium iodide symporter supports radionuclide imaging and treatment of breast cancer'. Stem Cells (Dayton, Ohio), 29 (7) [DOI] [Details]
(2010) 'Advances in mesenchymal stem cell-mediated gene therapy for cancer'
Dwyer RM, Khan S, Barry FP, O'Brien T and Kerin MJ (2010) 'Advances in mesenchymal stem cell-mediated gene therapy for cancer'. Stem Cell Research And Therapy, 1 (3) [Details]
(2010) 'Potential role of mesenchymal stem cells (MSCs) in the breast tumour microenvironment: stimulation of epithelial to mesenchymal transition (EMT)'
Martin FT, Dwyer RM, Kelly J, Khan S, Murphy JM, Curran C, Miller N, Hennessy E, Dockery P, Barry FP, O'Brien T, Kerin MJ. (2010) 'Potential role of mesenchymal stem cells (MSCs) in the breast tumour microenvironment: stimulation of epithelial to mesenchymal transition (EMT)'. Breast Cancer Res Treat, 124 (2):317-26 [Details]
(2010) 'Mesenchymal Stem Cells (MSCs) and Cancer: tumour specific delivery vehicles or therapeutic targets?'
Dwyer RM Kerin MJ (2010) 'Mesenchymal Stem Cells (MSCs) and Cancer: tumour specific delivery vehicles or therapeutic targets?'. Human Gene Therapy, 21 (11):1506-1512 [Details]
(2010) 'Dysregulated miR-183 inhibits migration in breast cancer cells'
Lowery, AJ, Miller, N, Dwyer, RM, Kerin, MJ (2010) 'Dysregulated miR-183 inhibits migration in breast cancer cells'. BMC Cancer, 10 [DOI] [Details]
(2009) 'Sodium iodide symporter (NIS) mediated tracking of mesenchymal stem cell (MSC) migration to breast tumours in vivo'
Dwyer R et al. (2009) 'Sodium iodide symporter (NIS) mediated tracking of mesenchymal stem cell (MSC) migration to breast tumours in vivo'. Human Gene Therapy, 20 (11) [Details]
(2009) 'Systemic chemokine levels in breast cancer patients and their relationship with circulating menstrual hormones'
Potter, SM,Dwyer, RM,Curran, CE,Hennessy, E,Harrington, KA,Griffin, DG,Kerin, MJ (2009) 'Systemic chemokine levels in breast cancer patients and their relationship with circulating menstrual hormones'. Breast Cancer Research And Treatment, 115 :279-287 [DOI] [Details]
(2009) 'Mesenchymal stem cell secretion of chemokines during differentiation into osteoblasts, and their potential role in mediating interactions with breast cancer cells'
Molloy, AP,Martin, FT,Dwyer, RM,Griffin, TP,Murphy, M,Barry, FP,O'Brien, T,Kerin, MJ (2009) 'Mesenchymal stem cell secretion of chemokines during differentiation into osteoblasts, and their potential role in mediating interactions with breast cancer cells'. International Journal Of Cancer, 124 :326-332 [DOI] [Details]
(2007) 'Monocyte Chemotactic Protein-1 (MCP-1) secreted by primary breast tumors stimulates migration of Mesenchymal Stem Cells (MSCs)'
Dwyer RM, Potter-Beirne SM, Harrington KA, Lowery AJ, Hennessy E, Murphy JM, Barry FP, O'Brien T, Kerin MJ (2007) 'Monocyte Chemotactic Protein-1 (MCP-1) secreted by primary breast tumors stimulates migration of Mesenchymal Stem Cells (MSCs)'. Clinical Cancer Research, 13 (17):5020-5027 [Details]
(2006) 'Sodium Iodide Symporter (NIS)-mediated Radioiodide Imaging and Therapy of Ovarian Tumor Xenografts in Mice'
Bergert ER, Gendler SJ, O'Connor MK and Morris JC (2006) 'Sodium Iodide Symporter (NIS)-mediated Radioiodide Imaging and Therapy of Ovarian Tumor Xenografts in Mice'. Gene Therapy, 13 (1):60-66 [Details]
(2006) 'Adenovirus-mediated and targeted expression of the sodium-iodide symporter permits in vivo radioiodide imaging and therapy of pancreatic tumors'
Bergert ER, Gendler SJ, O'Connor MK and Morris JC (2006) 'Adenovirus-mediated and targeted expression of the sodium-iodide symporter permits in vivo radioiodide imaging and therapy of pancreatic tumors'. Human Gene Therapy, 17 (6):661-668 [Details]
(2005) 'In Vivo Radioiodide Imaging and Treatment of Breast Cancer Xenografts Following MUC1-driven Expression of the Sodium Iodide Symporter (NIS)'
Bergert ER, Gendler SJ, O'Connor MK and Morris JC (2005) 'In Vivo Radioiodide Imaging and Treatment of Breast Cancer Xenografts Following MUC1-driven Expression of the Sodium Iodide Symporter (NIS)'. Cinical Cancer Research, 11 (4):1483-1489 [Details]
(2005) 'A Preclinical Large Animal Model of Adenovirus-Mediated Expression of the Sodium-Iodide Symporter for Radioiodide Imaging and Therapy of Locally Recurrent Prostate Cancer'
Schatz SM, Bergert ER, Myers RM, Harvey ME, Classic KL, Marler RJ, O'Connor MK and Morris JC (2005) 'A Preclinical Large Animal Model of Adenovirus-Mediated Expression of the Sodium-Iodide Symporter for Radioiodide Imaging and Therapy of Locally Recurrent Prostate Cancer'. Molecular Therapy, 12 (5):835-841 [Details]
(2002) 'The Sodium Iodide Symporter and Thyroid Disease'
Smyth PPA (2002) 'The Sodium Iodide Symporter and Thyroid Disease'. Clinical Endocrinology, 56 (4):427-429 [Details]
(2000) 'Tissue Iodine Content and Serum Mediated 125I Uptake Blocking Activity in Breast Cancer'
Kilbane MT, Ajjan RA, Weetman AP, Dwyer R, McDermott EWM, O'Higgins N J and Smyth PPA (2000) 'Tissue Iodine Content and Serum Mediated 125I Uptake Blocking Activity in Breast Cancer'. Journal of Clinical Endocrinology and Metabolism, 85 :1245-1250 [Details]

Abstract

  Year Publication
(2015) Exosome-Mediated Intercellular Communication in The Breast Tumour Microenvironment.
Joyce, D,Khan, S,O'Brien, K,Kerin, MJ,Dwyer, R (2015) Exosome-Mediated Intercellular Communication in The Breast Tumour Microenvironment. Abstract [Details]
(2015) Analysis of Exosome-Encapsulated MicroRNAs Secreted by Mesenchymal Stem Cells in Vitro.
Clancy, C,Brougham, C,Joyce, MR,Dwyer, RM,Kerin, MJ (2015) Analysis of Exosome-Encapsulated MicroRNAs Secreted by Mesenchymal Stem Cells in Vitro. Abstract [Details]
(2015) Photoacoustic Imaging in Breast Cancer.
Casey, MC,Zafar, H,Ennis, R,Walsh, S,Brown, J,Malone, C,McLaughlin, R,Sweeney, K,Dwyer, R,Leahy, M,Kerin, MJ (2015) Photoacoustic Imaging in Breast Cancer. Abstract [Details]
(2015) Clinical Application of Circulating Micrornas As Biomarkers is Hindered by Lack of Standardised Protocols.
Brien, KO,Ramphul, E,Malone, C,Kerin, MJ,Dwyer, RM (2015) Clinical Application of Circulating Micrornas As Biomarkers is Hindered by Lack of Standardised Protocols. Abstract [Details]
(2014) Exosomal Transfer of Micrornas as a Potential Path for Gene Therapy.
Joyce, D,Glynn, C,Khan, S,Brown, J,Dockery, P,Kerin, M,Dwyer, R (2014) Exosomal Transfer of Micrornas as a Potential Path for Gene Therapy. Abstract [Details]
(2013) Investigation of miR-504 expression in colorectal and breast cancer.
Hogan, N,Khan, S,Huong, Q,Brogham, C,Joyce, MR,Kerin, MJ,Dwyer, RM (2013) Investigation of miR-504 expression in colorectal and breast cancer. Abstract [Details]
(2013) Exosome-Mediated Active Transport of Selected Micrornas by Breast Cancer Cells.
Glynn, C,Kerin, MJ,Dwyer, R (2013) Exosome-Mediated Active Transport of Selected Micrornas by Breast Cancer Cells. Abstract [Details]
(2012) Three-Dimensional Co-culture of Mesenchymal Stem Cells With Colorectal Cancer Cells in Vitro Has a Distinct Effect on Cytokine Secretion.
Hogan, N,Dwyer, RM,Joyce, MR,Kerin, MJ (2012) Three-Dimensional Co-culture of Mesenchymal Stem Cells With Colorectal Cancer Cells in Vitro Has a Distinct Effect on Cytokine Secretion. Abstract [Details]
(2012) Identification of a Tumour Suppressor MiRNA That Correlates With RAR beta Expression in Breast Cancer.
Khan, S,Ryan, J,Brougham, C,Wall, D,Newell, J,Kerin, MJ,Dwyer, RM (2012) Identification of a Tumour Suppressor MiRNA That Correlates With RAR beta Expression in Breast Cancer. Abstract [Details]
(2009) Correlation of Sodium Iodide Symporter (NIS) and Retinoic Acid Receptor Alpha (RARA) expression in breast cancer.
Ryan, J,Hennessy, E,Curran, C,Morris, JC,Kerin, MJ,Dwyer, RM (2009) Correlation of Sodium Iodide Symporter (NIS) and Retinoic Acid Receptor Alpha (RARA) expression in breast cancer. Abstract [Details]
(2015) Exosome-mediated trafficking of microRNAs by breast cancer cells.
Joyce, DP,Glynn, CL,Brown, J,Holian, E,Dockery, P,Kerin, MJ,Dwyer, RM (2015) Exosome-mediated trafficking of microRNAs by breast cancer cells. Abstract [Details]
(2015) Potential role of photoacoustic imaging in neoadjuvant chemotherapy response monitoring in breast cancer.
Casey, MC,Ennis, R,Walsh, S,Brown, JAL,Dwyer, RM,Leahy, MJ,Kerin, MJ (2015) Potential role of photoacoustic imaging in neoadjuvant chemotherapy response monitoring in breast cancer. Abstract [Details]
(2015) Investigation of exosome-encapsulated microRNAs as potential circulating biomarkers of breast cancer.
Joyce, DP,Higgins, M,Glynn, CL,Brown, J,Holian, E,Dockery, P,Kerin, MJ,Dwyer, RM (2015) Investigation of exosome-encapsulated microRNAs as potential circulating biomarkers of breast cancer. Abstract [Details]
(2015) Secretion of Exosome-Encapsulated MicroRNAs by Breast Cancer Cell Lines.
Joyce, D,Glynn, C,Dockery, P,Dwyer, R,Kerin, M (2015) Secretion of Exosome-Encapsulated MicroRNAs by Breast Cancer Cell Lines. Abstract [Details]
(2015) Investigating a tumour-suppressor role for miR-379 in colorectal cancer.
Clancy, C,Khan, S,Glynn, CL,Joyce, MR,Kerin, MJ,Dwyer, RM (2015) Investigating a tumour-suppressor role for miR-379 in colorectal cancer. Abstract [Details]
(2015) Exosome-mediated trafficking of microRNAs by basal breast cancer cells in vitro.
Joyce, DP,Glynn, CL,Higgins, M,Brown, J,Holian, E,Dockery, P,Kerin, MJ,Dwyer, RM (2015) Exosome-mediated trafficking of microRNAs by basal breast cancer cells in vitro. Abstract [Details]
(2014) Secretion of exosome-encapsulated oncomiRs by colorectal cancer cells in vitro.
Clancy, C,Joyce, MR,Kerin, MJ,Dwyer, RM (2014) Secretion of exosome-encapsulated oncomiRs by colorectal cancer cells in vitro. Abstract [Details]
(2014) Exosome-mediated active and selective secretion of MicroRNAs by breast cancer cells in vitro.
Rahmani, LS,Glynn, CL,Dwyer, RM,Kerin, MJ (2014) Exosome-mediated active and selective secretion of MicroRNAs by breast cancer cells in vitro. Abstract [Details]
(2014) Investigation of exosome-encapsulated microRNA secretion in breast cancer.
Glynn, C,Khan, S,Brougham, C,Clancy, C,Joyce, D,Dockery, P,Kerin, MJ,Dwyer, RM (2014) Investigation of exosome-encapsulated microRNA secretion in breast cancer. Abstract [DOI] [Details]
(2014) Exosome-Encapsulated MicroRNAs Secreted by Colorectal Cancer Cells: Mediators of Intercellular Cross-Talk in the Tumour Micro-Environment.
Clancy, C,Brown, J,Holian, E,Joyce, M,Kerin, MJ,Dwyer, RM (2014) Exosome-Encapsulated MicroRNAs Secreted by Colorectal Cancer Cells: Mediators of Intercellular Cross-Talk in the Tumour Micro-Environment. Abstract [Details]
(2014) Secretion of Exosome-Encapsulated MicroRNAs by Basal Breast Cancer Cells in Vitro.
Joyce, D,Glynn, C,Brown, J,Holian, E,Dockery, P,Kerin, MJ,Dwyer, R (2014) Secretion of Exosome-Encapsulated MicroRNAs by Basal Breast Cancer Cells in Vitro. Abstract [Details]
(2012) Identification and Validation of a MicroRNA Signature Associated with Breast Cancer Progression.
Waters, PS,Dwyer, RM,Wall, D,McDermott, AM,Newell, J,Kerin, MJ (2012) Identification and Validation of a MicroRNA Signature Associated with Breast Cancer Progression. Abstract [Details]
(2011) Mesenchymal Stem Cell (MSC) mediated delivery of the Sodium Iodide Symporter (NIS) supports radionuclide imaging and treatment of breast cancer. American Association for Cancer Research, Orlando, Florida.
Dwyer RM, Ryan J, Havelin RJ, Morris JC, O'Flatharta C, Miller BW, Liu Z, Foley MJ, Barrett HH, Murphy M, Barry FP, O'Brien T and Kerin MJ (2011) Mesenchymal Stem Cell (MSC) mediated delivery of the Sodium Iodide Symporter (NIS) supports radionuclide imaging and treatment of breast cancer. American Association for Cancer Research, Orlando, Florida. Abstract [Details]
(2010) CORRELATION BETWEEN CIRCULATING AND TUMOUR TISSUE CCL5 AND TGF beta 1 IN BREAST CANCER PATIENTS.
Hartmann, MC,Dwyer, RM,Costello, M,Kerin, MJ (2010) CORRELATION BETWEEN CIRCULATING AND TUMOUR TISSUE CCL5 AND TGF beta 1 IN BREAST CANCER PATIENTS. Abstract [Details]
(2009) EFFECT OF MONOCYTE CHEMOTACTIC PROTEIN-1(MCP-1) ON BREAST CANCER CELL PROLIFERATION AND GENE EXPRESSION.
Hartmann, MC,Dwyer, RM,Boyle, MP,Potter, SM,Kerin, MJ (2009) EFFECT OF MONOCYTE CHEMOTACTIC PROTEIN-1(MCP-1) ON BREAST CANCER CELL PROLIFERATION AND GENE EXPRESSION. Abstract [Details]
(2009) Analysis of Primary Breast Tumour Stromal Cells and Their Potential Role in Disease Progression.
Hartmann, MC,Dwyer, RM,Kerin, MJ (2009) Analysis of Primary Breast Tumour Stromal Cells and Their Potential Role in Disease Progression. Abstract [Details]
(2009) Mesenchymal Stem Cell (MSC) secretion of TGF beta and VEGF stimulates Epithelial to Mesenchymal Transition (EMT) in breast cancer cell lines.
Kelly, J,Dwyer, RM,Murphy, M,Barry, FP,O'Brien, T,Kerin, MJ (2009) Mesenchymal Stem Cell (MSC) secretion of TGF beta and VEGF stimulates Epithelial to Mesenchymal Transition (EMT) in breast cancer cell lines. Abstract [Details]
(2009) Characterization of primary tumour stromal cells and their potential role in the breast cancer microenvironment.
Hartmann, MC,Dwyer, RM,Potter, SM,Dockery, P,Kerin, MJ (2009) Characterization of primary tumour stromal cells and their potential role in the breast cancer microenvironment. Abstract [Details]
(2009) Potential promotion of metastatis of circulating breast cancer cells through interactions with mesenchymal stem cells (MSCs).
Martin, FT,Dwyer, RM,Murphy, MJ,Barry, FP,Brien, TO,Kerin, MJ (2009) Potential promotion of metastatis of circulating breast cancer cells through interactions with mesenchymal stem cells (MSCs). Abstract [Details]
(2009) Stromal-epithelial cell cross-talk in the breast tumour microenvironment elicits changes in tumour epithelial cell gene expression.
Potter, SM,Dwyer, RM,Kerin, MJ (2009) Stromal-epithelial cell cross-talk in the breast tumour microenvironment elicits changes in tumour epithelial cell gene expression. Abstract [Details]
(2008) Hormonal regulation of breast cancer associated chemokines.
Potter, S,Dwyer, RM,Hennessy, E,Griffin, DG,Kerin, MJ (2008) Hormonal regulation of breast cancer associated chemokines. Abstract [Details]
(2008) Investigation of the potential of mesenchymal stem cells (MSCs) for gene delivery to breast tumours.
Dwyer, RM,Morris, JC,Murphy, M,Barry, FP,O'Brien, T,Kenn, MJ (2008) Investigation of the potential of mesenchymal stem cells (MSCs) for gene delivery to breast tumours. Abstract [Details]
(2008) Elevated plasma sdf-1 alpha in breast cancer patients correlates with tumour grade.
Potter, S,Dwyer, R,Harrington, K,Kerin, M (2008) Elevated plasma sdf-1 alpha in breast cancer patients correlates with tumour grade. Abstract [Details]
(2008) Marrow-derived mesenchymal stem cells (MSCs) stimulate breast cancer cell secretion and expression of chemokines.
Martin, FT,Dwyer, RM,Murphy, JM,Barry, FP,O'Brien, T,Kerin, MJ (2008) Marrow-derived mesenchymal stem cells (MSCs) stimulate breast cancer cell secretion and expression of chemokines. Abstract [Details]
(2007) Myocardial Infarct-Produced Chemokine Stimulus Promotes Stem Cell Migration. Irish Society for Gene and Cell Therapy, Regenerative Medicine Institute (REMEDI), National University of Ireland, Galway, Ireland.
Kavanagh C, Sloane P, Dwyer R, Coleman CM, O'Brien T, Barry F (2007) Myocardial Infarct-Produced Chemokine Stimulus Promotes Stem Cell Migration. Irish Society for Gene and Cell Therapy, Regenerative Medicine Institute (REMEDI), National University of Ireland, Galway, Ireland. Abstract [Details]
(2007) Investigation of the potential of human mesenchymal stem cells (hMSC) as vectors for therapeutic gene delivery to breast tumours.
Dwyer, RM,Barry, FP,O'Brien, T,Kerin, MJ (2007) Investigation of the potential of human mesenchymal stem cells (hMSC) as vectors for therapeutic gene delivery to breast tumours. Abstract [Details]
(2007) The potential role of bone derived cells in the development of breast cancer metastases.
Molloy, AP,Dwyer, RM,Kerin, MJ (2007) The potential role of bone derived cells in the development of breast cancer metastases. Abstract [Details]
(2007) Myocardial Infarct-Produced Chemokine Stimulus Promotes Stem Cell Migration. Proceedings of the 5th International Society For Stem Cell Research.
Kavanagh C, Sloane P, Dwyer R, Coleman CM, O'Brien T, Barry F (2007) Myocardial Infarct-Produced Chemokine Stimulus Promotes Stem Cell Migration. Proceedings of the 5th International Society For Stem Cell Research. Cairns, Australia: Abstract [Details]
(2007) Osteoblasts and their progenitors stimulate breast cancer cell migration through chemokine secretion.
Molloy, AP,Dwyer, RM,Kerin, MJ (2007) Osteoblasts and their progenitors stimulate breast cancer cell migration through chemokine secretion. Abstract [Details]
(2007) Distinct chemokines mediate tumourigenicity of breast cancer cells.
Potter, SM,Dwyer, RM,Kerin, MJ (2007) Distinct chemokines mediate tumourigenicity of breast cancer cells. Abstract [Details]

ANET/COS

  Year Publication
(2009) European Journal of Cancer Supplements 7 (2), 89.
Kelly, J,Dwyer, RM,Murphy, M,Barry, FP,O'Brien, T,Kerin, MJ (2009) European Journal of Cancer Supplements 7 (2), 89. ANET/COS [Details]
(2009) Orthopedics.
Molloy AP, Martin FT, Dwyer RM, Griffin TP, Murphy M, Barry FP, O'Brien T, Kerin MJ. (2009) Orthopedics. ANET/COS [DOI] [Details]
(2008) European Journal of Cancer Supplements 6 (9).
Dwyer, RM,Morris, JC,Murphy, M,Barry, FP,O'Brien, T,Kerin, MJ (2008) European Journal of Cancer Supplements 6 (9). ANET/COS [Details]

Book Review

  Year Publication
(2016) An evaluation of multiple novel markers expression on breast cancer recurrence and outcome.
Cuggy, C,Elwahab, SA,Khan, S,Dwyer, RM,Sweeney, KJ,McLaughlin, R,Kerins, MJ,Malone, C (2016) An evaluation of multiple novel markers expression on breast cancer recurrence and outcome. Book Review [Details]

Conference Paper

  Year Publication
(2011) Cellular Interactions in the Primary Tumour Microenvironment. Sir Peter Freyer Surgical Symposium.
Sonja Khan, Roisin M Dwyer, Karl J Sweeney and Michael J Kerin (2011) Cellular Interactions in the Primary Tumour Microenvironment. Sir Peter Freyer Surgical Symposium. Conference Paper [Details]
(2010) Potential role for thyroid hormones in regulation of mammary Sodium Iodide Symporter expression. Sir Peter Freyer Surgical Symposium.
J. Ryan, C.C. Curran, E. Hennessy, J.C. Morris, M.J. Kerin and R.M. Dwyer (2010) Potential role for thyroid hormones in regulation of mammary Sodium Iodide Symporter expression. Sir Peter Freyer Surgical Symposium. Conference Paper [Details]
(2010) Breast Tumour Stromal-Epithelial Interactions Stimulate Increased VEGF Secretion And Angiogenesis In Vitro and In Vivo.. Sir Peter Freyer Surgical Symposium.
S Khan, RM Dwyer, SM Potter and MJ Kerin (2010) Breast Tumour Stromal-Epithelial Interactions Stimulate Increased VEGF Secretion And Angiogenesis In Vitro and In Vivo.. Sir Peter Freyer Surgical Symposium. Conference Paper [Details]
(2010) Potential of circulating chemokines as serum tumour markers in breast cancer. Society of Academic & Research Surgery (SARS).
Costello M, Hartmann MC, Dwyer RM, Kerin MJ (2010) Potential of circulating chemokines as serum tumour markers in breast cancer. Society of Academic & Research Surgery (SARS). Conference Paper [Details]
(2010) Correlation between circulating and tumour tissue CCL5 and TGFß1 in breast cancer patients. Sir Peter Freyer Surgical Symposium.
Hartmann MC, Dwyer RM, Costello M, Kerin MJ (2010) Correlation between circulating and tumour tissue CCL5 and TGFß1 in breast cancer patients. Sir Peter Freyer Surgical Symposium. Conference Paper [Details]
(2010) Investigation of potential role of CCL5 in breast cancer progression. Sylvester O Halloran Surgical Symposium.
Hartmann MC, Dwyer RM, Costello M, Kerin MJ (2010) Investigation of potential role of CCL5 in breast cancer progression. Sylvester O Halloran Surgical Symposium. Conference Paper [Details]
(2009) Mesenchymal Stem Cells (MSCs) may promote breast cancer metastatic potential through stimulation of Epithelial-Mesenchymal Transition (EMT). Society of Academic & Research Surgery (SARS).
FT Martin, RM Dwyer, JM Murphy, N Miller, FP Barry, T O'Brien and MJ Kerin (2009) Mesenchymal Stem Cells (MSCs) may promote breast cancer metastatic potential through stimulation of Epithelial-Mesenchymal Transition (EMT). Society of Academic & Research Surgery (SARS). Conference Paper [Details]
(2009) Expression of the sodium iodide symporter in breast cancer. Sir Peter Freyer Surgical Symposium.
J. Ryan, E. Hennessey, C.C. Curran, J.C. Morris, M.J. Kerin and R.M. Dwyer (2009) Expression of the sodium iodide symporter in breast cancer. Sir Peter Freyer Surgical Symposium. Conference Paper [Details]
(2009) Mesenchymal stem cells and breast cancer: therapeutic delivery vehicles or tumour promoting agents. Sir Peter Freyer Surgical Symposium.
John C Kelly, Roisin M. Dwyer, Mary Murphy, Frank P Barry, Timothy O'Brien and Michael J. Kerin (2009) Mesenchymal stem cells and breast cancer: therapeutic delivery vehicles or tumour promoting agents. Sir Peter Freyer Surgical Symposium. Conference Paper [Details]
(2009) Paracrine impact of Mesenchymal Stem Cells (MSCs) on breast cancer cell gene expression. Sylvester O Halloran Surgical Symposium.
John C Kelly, Roisin M. Dwyer, Fiachra T Martin, Mary Murphy, Frank P Barry, Timothy O'Brien and Michael J. Kerin (2009) Paracrine impact of Mesenchymal Stem Cells (MSCs) on breast cancer cell gene expression. Sylvester O Halloran Surgical Symposium. Conference Paper [Details]
(2009) TUMOUR PROMOTING ROLE OF PRIMARY STROMAL CELLS IN THE BREAST CANCER MICROENVIRONMENT IN VIVO AND IN VITRO. Irish Association for Cancer Research (IACR).
Shirley M Potter, Roisin M Dwyer, Marie P Boyle, Marion C Hartmann, Catherine E Curran, Emer Hennessy and Michael J Kerin. (2009) TUMOUR PROMOTING ROLE OF PRIMARY STROMAL CELLS IN THE BREAST CANCER MICROENVIRONMENT IN VIVO AND IN VITRO. Irish Association for Cancer Research (IACR). Conference Paper [Details]
(2009) Potential role of Monocyte Chemotactic Protein-1 (MCP-1) in the Breast Cancer Microenvironment. Sylvester O Halloran Surgical Symposium.
M.C. Hartmann, R.M. Dwyer, M.P. Boyle, S.M. Potter and M.J. Kerin (2009) Potential role of Monocyte Chemotactic Protein-1 (MCP-1) in the Breast Cancer Microenvironment. Sylvester O Halloran Surgical Symposium. Conference Paper [Details]
(2009) Potential promotion of metastatis of circulating breast cancer cells through interactions with mesenchymal stem cells (MSCs). CANCER RESEARCH.
Martin, FT,Dwyer, RM,Murphy, MJ,Barry, FP,Brien, TO,Kerin, MJ (2009) Potential promotion of metastatis of circulating breast cancer cells through interactions with mesenchymal stem cells (MSCs). CANCER RESEARCH. Conference Paper [Details]
(2009) Sodium iodide symporter (NIS) mediated tracking of mesenchymal stem cell (MSC) migration to breast tumours in vivo. European Society for Gene and Cell Therapy (ESGCT).
Dwyer R, Ryan J, Havelin R, Morris J, O'Flatharta C, Duffy G, Miller B, Liu ZL, Barrett H, Murphy M, Barry F, O'Brien T, Kerin M (2009) Sodium iodide symporter (NIS) mediated tracking of mesenchymal stem cell (MSC) migration to breast tumours in vivo. European Society for Gene and Cell Therapy (ESGCT). Conference Paper [Details]
(2009) Interactions between Mesenchymal Stem Cells (MSCs) and Breast Cancer Cells support induction of Epithelial - Mesenchymal Transition (EMT). Irish Association for Cancer Research (IACR).
FT Martin, RM Dwyer, J Kelly, JM Murphy, N Miller, E Hennessy, C Curran, FP Barry, T O'Brien, MJ Kerin (2009) Interactions between Mesenchymal Stem Cells (MSCs) and Breast Cancer Cells support induction of Epithelial - Mesenchymal Transition (EMT). Irish Association for Cancer Research (IACR). Conference Paper [Details]
(2009) Characterisation of primary tumour stromal cells and their role in the breast tumour microenvironment. Sir Peter Freyer Surgical Symposium.
M.C. Hartmann, R.M. Dwyer, S.M. Potter, M.P. Boyle and M.J. Kerin. (2009) Characterisation of primary tumour stromal cells and their role in the breast tumour microenvironment. Sir Peter Freyer Surgical Symposium. Conference Paper [Details]
(2008) Marrow-Derived Mesenchymal Stem Cells (MSCs) stimulate chemokine secretion and alter gene expression in breast cancer cells. Association of Surgeons of Great Britain and Ireland (ASGBI).
FT Martin, RM Dwyer, TP Griffin, JM Murphy, FP Barry, T O'Brien and MJ Kerin (2008) Marrow-Derived Mesenchymal Stem Cells (MSCs) stimulate chemokine secretion and alter gene expression in breast cancer cells. Association of Surgeons of Great Britain and Ireland (ASGBI). Conference Paper [Details]
(2008) The Role of Bone-Derived Mesenchymal Stem Cells (MSCs) in Facilitating Breast Cancer Metastasis. Sylvester O Halloran Surgical Symposium.
FT Martin, RM Dwyer, TP Griffin, JM Murphy, FP Barry, T O'Brien and MJ Kerin (2008) The Role of Bone-Derived Mesenchymal Stem Cells (MSCs) in Facilitating Breast Cancer Metastasis. Sylvester O Halloran Surgical Symposium. Conference Paper [Details]
(2007) Investigation of the Potential of Human Mesenchymal Stem Cells (hMSC) as Vectors for Therapeutic Gene Delivery to Breast Tumours. Irish Society for Gene and Cell Therapy (ISGCT).
RM Dwyer, FP Barry, T O'Brien and MJ Kerin. (2007) Investigation of the Potential of Human Mesenchymal Stem Cells (hMSC) as Vectors for Therapeutic Gene Delivery to Breast Tumours. Irish Society for Gene and Cell Therapy (ISGCT). Conference Paper [Details]
(2007) The role of Chemokine production by Primary Breast Cancer Stromal Cells in tumour progression.. Association of Surgeons of Great Britain and Ireland (ASGBI).
Shirley M Potter-Beirne, Roisin M Dwyer, Micheal J Kerin (2007) The role of Chemokine production by Primary Breast Cancer Stromal Cells in tumour progression.. Association of Surgeons of Great Britain and Ireland (ASGBI). Conference Paper [Details]
(2007) Mesenchymal Stem Cells (MSCs) as Potential Vectors for Delivery of Therapeutic Agents to Breast Tumours. NBCRI/NCBES Breast Cancer Research Day.
RM Dwyer, FP Barry, T O'Brien and MJ Kerin. (2007) Mesenchymal Stem Cells (MSCs) as Potential Vectors for Delivery of Therapeutic Agents to Breast Tumours. NBCRI/NCBES Breast Cancer Research Day. Conference Paper [Details]
(2007) The potential role of bone-derived cells in development of breast cancer metastases. Sir Peter Freyer Surgical Symposium.
AP Molloy, RM Dwyer and MJ Kerin (2007) The potential role of bone-derived cells in development of breast cancer metastases. Sir Peter Freyer Surgical Symposium. Conference Paper [Details]

Conference Poster

  Year Publication
(2011) Mesenchymal Stem Cell (MSC) mediated delivery of the Sodium Iodide Symporter (NIS) supports radionuclide imaging and treatment of breast cancer. American Association for Cancer Research (AACR).
Roisin M. Dwyer, James Ryan, Ronan Havelin, John C. Morris, Cathal O'Flatharta, Brian Miller, Zhonglin Liu, Mark Foley, Harrison H. Barrett, Mary Murphy, Frank P. Barry, Timothy O'Brien and Michael J. Kerin. (2011) Mesenchymal Stem Cell (MSC) mediated delivery of the Sodium Iodide Symporter (NIS) supports radionuclide imaging and treatment of breast cancer. American Association for Cancer Research (AACR). Conference Poster [Details]
(2010) Potential Role of Primary Breast Cancer Stromal Cells in the Development of Endocrine Resistance. Irish Association for Cancer Research (IACR).
S Khan, RM Dwyer, MC Hartmann and MJ Kerin (2010) Potential Role of Primary Breast Cancer Stromal Cells in the Development of Endocrine Resistance. Irish Association for Cancer Research (IACR). Conference Poster [Details]
(2010) Expression of the Sodium Iodide Symporter and potential regulators in Normal, Benign and Malignant breast tissue. Irish Association for Cancer Research (IACR).
J. Ryan, C.C. Curran, E. Hennessy, J.C. Morris, M.J. Kerin and R.M. Dwyer (2010) Expression of the Sodium Iodide Symporter and potential regulators in Normal, Benign and Malignant breast tissue. Irish Association for Cancer Research (IACR). Conference Poster [Details]
(2010) Circulating and tumour tissue levels of CCL5/RANTES in breast cancer. Irish Association for Cancer Research (IACR).
Hartmann MC, Dwyer RM, Costello M, Kerin MJ (2010) Circulating and tumour tissue levels of CCL5/RANTES in breast cancer. Irish Association for Cancer Research (IACR). Conference Poster [Details]
(2010) CCL5 in Breast Cancer: Circulating systemic levels and gene expression in the primary tumour microenvironment. American Association for Cancer Research (AACR).
Hartmann MC, Dwyer RM, Costello M, Kerin MJ (2010) CCL5 in Breast Cancer: Circulating systemic levels and gene expression in the primary tumour microenvironment. American Association for Cancer Research (AACR). Conference Poster [Details]
(2009) Effect of Monocyte Chemotactic Protein-1 (MCP-1) on breast cancer cell proliferation and gene expression. Targeted AntiCancer Therapies (TAT), , 23rd-25th March 2009.
Marion C Hartmann, Roisin M Dwyer, Marie P Boyle, Shirley M Potter and Prof Michael J Kerin (2009) Effect of Monocyte Chemotactic Protein-1 (MCP-1) on breast cancer cell proliferation and gene expression. Targeted AntiCancer Therapies (TAT), , 23rd-25th March 2009. Conference Poster [Details]
(2009) Potential Role of Mesenchymal Stem Cells (MSCs) in the Breast Tumour Microenvironment: Stimulation of Epithelial to Mesenchymal Transition (EMT). American Association for Cancer Research (AACR).
FT Martin, RM Dwyer, JM Murphy, N Miller, FP Barry, T O'Brien and MJ Kerin (2009) Potential Role of Mesenchymal Stem Cells (MSCs) in the Breast Tumour Microenvironment: Stimulation of Epithelial to Mesenchymal Transition (EMT). American Association for Cancer Research (AACR). Conference Poster [Details]
(2009) Analysis of primary breast tumour stromal cells and their potential role in disease progression. San Antonio Breast Cancer Symposium.
M.C. Hartmann, R.M. Dwyer and M.J. Kerin (2009) Analysis of primary breast tumour stromal cells and their potential role in disease progression. San Antonio Breast Cancer Symposium. Conference Poster [Details]
(2009) Role of Stromal-Epithelial interactions in the primary breast tumour microenvironment in vitro and in vivo. American Association for Cancer Research (AACR).
Shirley M Potter, Roisin M Dwyer, Marie P Boyle, Marion C Hartmann, Catherine E Curran, Emer Hennessy and Michael J Kerin. (2009) Role of Stromal-Epithelial interactions in the primary breast tumour microenvironment in vitro and in vivo. American Association for Cancer Research (AACR). Conference Poster [Details]
(2009) Correlation of Sodium Iodide Symporter (NIS) and Retinoic Acid Receptor Alpha (RARA) expression in breast cancer. European Cancer Organisation (ECCO)/ESMO.
J. Ryan, E. Hennessy, C.C. Curran, J.C. Morris, M.J. Kerin and R.M. Dwyer (2009) Correlation of Sodium Iodide Symporter (NIS) and Retinoic Acid Receptor Alpha (RARA) expression in breast cancer. European Cancer Organisation (ECCO)/ESMO. Conference Poster [Details]
(2009) Mesenchymal Stem Cell (MSC) secretion of TGFb and VEGF stimulates Epithelial to Mesenchymal Transition (EMT) in breast cancer cell lines. European Cancer Organisation (ECCO)/ESMO.
John C Kelly, Roisin M. Dwyer, Mary Murphy, Frank P Barry, Timothy O'Brien and Michael J. Kerin (2009) Mesenchymal Stem Cell (MSC) secretion of TGFb and VEGF stimulates Epithelial to Mesenchymal Transition (EMT) in breast cancer cell lines. European Cancer Organisation (ECCO)/ESMO. Conference Poster [Details]
(2009) Characterization of primary tumour stromal cells and their potential role in the breast cancer microenvironment. European Cancer Organisation (ECCO)/ESMO.
M.C. Hartmann, R.M. Dwyer, S.M. Potter, P Dockery and M.J. Kerin. (2009) Characterization of primary tumour stromal cells and their potential role in the breast cancer microenvironment. European Cancer Organisation (ECCO)/ESMO. Conference Poster [Details]
(2009) DISTINCT PROPERTIES OF BREAST TUMOUR COMPARED TO NORMAL STROMAL CELLS AND THEIR INFLUENCE ON BREAST CANCER EPITHELIAL CELL GENE EXPRESSION. Society of Academic & Research Surgery (SARS).
Shirley M Potter, Marie P Boyle, Roisin M Dwyer, Nicola Miller and Micheal J Kerin. (2009) DISTINCT PROPERTIES OF BREAST TUMOUR COMPARED TO NORMAL STROMAL CELLS AND THEIR INFLUENCE ON BREAST CANCER EPITHELIAL CELL GENE EXPRESSION. Society of Academic & Research Surgery (SARS). Conference Poster [Details]
(2008) Stromal-epithalial cell Cross-talk In The Breast Tumour Microenvironment Elicits Changes In Gene Expression in Breast Cancer Epithelial Cells. San Antonio Breast Cancer Symposium.
Shirley M Potter, Roisin M Dwyer, Michael J Kerin (2008) Stromal-epithalial cell Cross-talk In The Breast Tumour Microenvironment Elicits Changes In Gene Expression in Breast Cancer Epithelial Cells. San Antonio Breast Cancer Symposium. Conference Poster [Details]
(2008) Potential promotion of the metastatic potential of circulating Breast Cancer Cells through interactions with Mesenchymal Stem Cells (MSCs). San Antonio Breast Cancer Symposium.
FT Martin, RM Dwyer, JM Murphy, FP Barry, T O'Brien and MJ Kerin (2008) Potential promotion of the metastatic potential of circulating Breast Cancer Cells through interactions with Mesenchymal Stem Cells (MSCs). San Antonio Breast Cancer Symposium. Conference Poster [Details]
(2008) Hormonal regulation of breast cancer associated chemokines. European Association for Cancer Research (EACR).
Shirley M. Potter, Roisin M. Dwyer, Emer Hennessy, Damien Griffin and Michael J. Kerin. (2008) Hormonal regulation of breast cancer associated chemokines. European Association for Cancer Research (EACR). Conference Poster [Details]
(2008) Sodium Iodide Symporter (NIS) mediated Iodide Uptake in Mesenchymal Stem Cells following Adenoviral Transduction. American Society of Gene Therapy (ASGT).
RM Dwyer, JC Morris, JM Murphy, FP Barry, T O'Brien and MJ Kerin. (2008) Sodium Iodide Symporter (NIS) mediated Iodide Uptake in Mesenchymal Stem Cells following Adenoviral Transduction. American Society of Gene Therapy (ASGT). Conference Poster [Details]
(2008) Next Generation Mesenchymal Stem Cells for Regenerative Medicine Applications: Antibodies, Peptides and Lipoplexes for isolation, expansion and genetic modification of MSCs from several species. Irish Society for Gene and Cell Therapy (ISGCT).
Udo Greiser, Melissa Hoare, Tyrone Bowes, Roisin Dwyer, Daniel O'Toole, Kaveh Mashayekhi, Mary Murphy, Frank Barry and Timothy O'Brien (2008) Next Generation Mesenchymal Stem Cells for Regenerative Medicine Applications: Antibodies, Peptides and Lipoplexes for isolation, expansion and genetic modification of MSCs from several species. Irish Society for Gene and Cell Therapy (ISGCT). Conference Poster [Details]
(2008) Circulating Stromal Cell Derived Factor-1a (SDF-1a) in Premenopausal Women is Influenced by Phase of Menstrual Cycle. Association of Surgeons of Great Britain and Ireland (ASGBI).
Shirley M. Potter, Roisin M. Dwyer, Emer Hennessy, Damien Griffin and Michael J. Kerin. (2008) Circulating Stromal Cell Derived Factor-1a (SDF-1a) in Premenopausal Women is Influenced by Phase of Menstrual Cycle. Association of Surgeons of Great Britain and Ireland (ASGBI). Conference Poster [Details]
(2008) Circulating Stromal Cell Derived Factor-1a (SDF-1a) in Premenopausal Women is Influenced by Phase of Menstrual Cycle. Sir Peter Freyer Surgical Symposium.
Shirley M. Potter, Roisin M. Dwyer, Emer Hennessy, Damian G. Griffin and Michael J. Kerin. (2008) Circulating Stromal Cell Derived Factor-1a (SDF-1a) in Premenopausal Women is Influenced by Phase of Menstrual Cycle. Sir Peter Freyer Surgical Symposium. Conference Poster [Details]
(2008) Investigation of the potential of Mesenchymal Stem Cells (MSCs) for gene delivery to breast tumours. European Association for Cancer Research (EACR).
RM Dwyer, JC Morris, JM Murphy, FP Barry, T O'Brien and MJ Kerin. (2008) Investigation of the potential of Mesenchymal Stem Cells (MSCs) for gene delivery to breast tumours. European Association for Cancer Research (EACR). Conference Poster [Details]
(2008) Marrow-Derived Mesenchymal Stem Cells (MSCs) stimulate chemokine secretion and gene expression in breast cancer cells. European Association for Cancer Research (EACR).
FT Martin, RM Dwyer, TP Griffin, JM Murphy, FP Barry, T O'Brien and MJ Kerin (2008) Marrow-Derived Mesenchymal Stem Cells (MSCs) stimulate chemokine secretion and gene expression in breast cancer cells. European Association for Cancer Research (EACR). Conference Poster [Details]
(2008) Sodium Iodide Symporter (NIS) mediated Iodide Uptake in Mesenchymal Stem Cells following Adenoviral Transduction. Irish Society for Gene and Cell Therapy (ISGCT).
RM Dwyer, JC Morris, JM Murphy, FP Barry, T O'Brien and MJ Kerin. (2008) Sodium Iodide Symporter (NIS) mediated Iodide Uptake in Mesenchymal Stem Cells following Adenoviral Transduction. Irish Society for Gene and Cell Therapy (ISGCT). Conference Poster [Details]
(2007) Role of Osteoblasts in Promoting Breast Cancer Cell Migration and Proliferation. Irish Association for Cancer Research.
AP Molloy, RM Dwyer, MJ Kerin (2007) Role of Osteoblasts in Promoting Breast Cancer Cell Migration and Proliferation. Irish Association for Cancer Research. Conference Poster [Details]
(2007) Analysis of the role of osteogenic cells in breast cancer metastasis. Association of Surgeons of Great Britain and Ireland (ASGBI).
AP Molloy, RM Dwyer, MJ Kerin (2007) Analysis of the role of osteogenic cells in breast cancer metastasis. Association of Surgeons of Great Britain and Ireland (ASGBI). Conference Poster [Details]
(2007) The Role of Primary Stromal Cell-derived Chemokines in the Breast Tumour Microenvironment. European Cancer Organisation (ECCO).
Shirley M Potter-Beirne, Roisin M Dwyer and Michael J Kerin (2007) The Role of Primary Stromal Cell-derived Chemokines in the Breast Tumour Microenvironment. European Cancer Organisation (ECCO). Conference Poster [Details]
(2007) Osteoblasts and their progenitors stimulate breast cancer cell migration through chemokine secretion. San Antonio Breast Cancer Symposium.
Molloy AP, Dwyer RM, Kerin MJ. (2007) Osteoblasts and their progenitors stimulate breast cancer cell migration through chemokine secretion. San Antonio Breast Cancer Symposium. Conference Poster [Details]
(2007) Distinct Chemokines Mediate Tumourigenicity of Breast Cancer Cells. San Antonio Breast Cancer Symposium.
Shirley Potter Beirne, Roisin Dwyer, and Michael Kerin. (2007) Distinct Chemokines Mediate Tumourigenicity of Breast Cancer Cells. San Antonio Breast Cancer Symposium. Conference Poster [Details]
(2007) The potential role of bone derived cells in the development of breast cancer metastases. European Cancer Organisation (ECCO).
AP Molloy, RM Dwyer, MJ Kerin (2007) The potential role of bone derived cells in the development of breast cancer metastases. European Cancer Organisation (ECCO). Conference Poster [Details]
(2007) Investigation of the potential of human Mesenchymal Stem Cells (hMSC) as vectors for therapeutic gene delivery to breast tumours. European Cancer Organisation (ECCO).
R.M. Dwyer, F.P. Barry, T. O'Brien, M.J. Kerin. (2007) Investigation of the potential of human Mesenchymal Stem Cells (hMSC) as vectors for therapeutic gene delivery to breast tumours. European Cancer Organisation (ECCO). Conference Poster [Details]
(2007) The role of Chemokine production by Primary Breast Cancer Stromal Cells in tumour progression.. Irish Association for Cancer Research.
Shirley M Potter-Beirne, Roisin M Dwyer, Micheal J Kerin (2007) The role of Chemokine production by Primary Breast Cancer Stromal Cells in tumour progression.. Irish Association for Cancer Research. Conference Poster [Details]
(2007) Bone Marrow-Derived Mesenchymal Stem Cells (MSCs) as potential interacting targets for circulating breast cancer cells. Irish Association for Cancer Research.
RM Dwyer, FP Barry, T O'Brien and MJ Kerin. (2007) Bone Marrow-Derived Mesenchymal Stem Cells (MSCs) as potential interacting targets for circulating breast cancer cells. Irish Association for Cancer Research. Conference Poster [Details]
(2007) Secretion and Expression of Monocyte Chemotactic Protein-1 (MCP-1) by Primary Breast Cancer Cell Populations.. Society of Academic & Research Surgery (SARS).
Shirley Potter Beirne, Roisin M Dwyer, Professor Micheal J Kerin (2007) Secretion and Expression of Monocyte Chemotactic Protein-1 (MCP-1) by Primary Breast Cancer Cell Populations.. Society of Academic & Research Surgery (SARS). Conference Poster [Details]
(2006) Mesenchymal stem cell-mediated stimulation of breast cancer cell migration. European Association for Cancer Research (EACR).
RM Dwyer, FP Barry, T O'Brien and MJ Kerin. (2006) Mesenchymal stem cell-mediated stimulation of breast cancer cell migration. European Association for Cancer Research (EACR). Conference Poster [Details]

Meeting

  Year Publication
(2007) The role of primary stromal cell-derived chemokines in the breast tumour microenvironment.
Potter, SM,Dwyer, RM,Kerin, MJ (2007) The role of primary stromal cell-derived chemokines in the breast tumour microenvironment. Meeting [Details]
(2007) The role of primary stromal cell-derived chemokines in the breast tumour microenvironment.
Potter-Beirne, S,Dwyer, R,Kerin, MJ (2007) The role of primary stromal cell-derived chemokines in the breast tumour microenvironment. Meeting [Details]
(2008) Next generation mesenchymal stem cells for regenerative medicine applications: antibodies, peptides and lipoplexes for isolation, expansion and genetic modification of mscs.
Greiser, U,Hoare, M,Bowes, T,Dwyer, R,O'Toole, D,Mashayekhi, K,Murphy, M,O'Brien, T,Barry, F (2008) Next generation mesenchymal stem cells for regenerative medicine applications: antibodies, peptides and lipoplexes for isolation, expansion and genetic modification of mscs. Meeting [Details]
(2009) Sodium iodide symporter (NIS) mediated tracking of mesenchymal stem cell (MSC) migration to breast tumours in vivo.
Dwyer, R,Ryan, J,Havelin, R,Morris, J,O'Flatharta, C,Duffy, G,Miller, B,Liu, ZL,Barrett, H,Murphy, M,Barry, F,O'Brien, T,Kerin, M (2009) Sodium iodide symporter (NIS) mediated tracking of mesenchymal stem cell (MSC) migration to breast tumours in vivo. Meeting [Details]
(2010) BREAST TUMOUR STROMAL-EPITHELIAL INTERACTIONS STIMULATE INCREASED VEGF SECRETION AND ANGIOGENESIS IN VITRO AND IN VIVO.
Khan, S,Dwyer, RM,Potter, SM,Kerin, MJ (2010) BREAST TUMOUR STROMAL-EPITHELIAL INTERACTIONS STIMULATE INCREASED VEGF SECRETION AND ANGIOGENESIS IN VITRO AND IN VIVO. Meeting [Details]
(2010) DIGIT RATIO (2D:4D) AS A PREDICTOR OF BREAST CANCER PREDISPOSITION.
Devine, A,Kelly, J,Heneghan, H,Dwyer, R,Kerin, M (2010) DIGIT RATIO (2D:4D) AS A PREDICTOR OF BREAST CANCER PREDISPOSITION. Meeting [Details]
(2010) INVESTIGATION OF POTENTIAL ROLE OF CCL5 IN BREAST CANCER PROGRESSION.
Hartmann, MC,Dwyer, RM,Costello, M,Kerin, MJ (2010) INVESTIGATION OF POTENTIAL ROLE OF CCL5 IN BREAST CANCER PROGRESSION. Meeting [Details]
(2010) Potential of circulating chemokines as serum tumour markers in breast cancer.
Costello, M,Hartmann, M,Dwyer, R,Kerin, M (2010) Potential of circulating chemokines as serum tumour markers in breast cancer. Meeting [Details]
(2010) POTENTIAL ROLE FOR THYROID HORMONES IN REGULATION OF MAMMARY NIS EXPRESSION.
Ryan, J,Hennessy, E,Curran, CC,Morris, JC,Kerin, MJ,Dwyer, RM (2010) POTENTIAL ROLE FOR THYROID HORMONES IN REGULATION OF MAMMARY NIS EXPRESSION. Meeting [Details]
(2011) Cellular interactions in the primary tumour microenvironment.
Khan, S,Dwyer, RM,Sweeney, KJ,Kerin, MJ (2011) Cellular interactions in the primary tumour microenvironment. Meeting [Details]
(2011) TGF-beta 1 mediated stimulation of VEGF secretion by breast cancer cells.
Costello, M,Dwyer, RM,Ryan, J,Hartmann, M,Kerin, MJ (2011) TGF-beta 1 mediated stimulation of VEGF secretion by breast cancer cells. Meeting [Details]
(2012) Mesenchymal stem cells (MSCs) and colorectal cancer.
Hogan, NM,Dwyer, RM,Joyce, MR,Kerin, MJ (2012) Mesenchymal stem cells (MSCs) and colorectal cancer. Meeting [Details]
(2012) Plasminogen activator inhibitor-1 (PAI-1) secretion by mesenchymal stem cells and colorectal cancer cells in 3-dimensional culture.
Hogan, NM,Dwyer, RM,Joyce, MR,Kerin, MJ (2012) Plasminogen activator inhibitor-1 (PAI-1) secretion by mesenchymal stem cells and colorectal cancer cells in 3-dimensional culture. Meeting [Details]
(2012) Analysis of miR10b expression during disease progression in a murine model of breast cancer.
Waters, PS,Dwyer, RM,Kerin, MJ (2012) Analysis of miR10b expression during disease progression in a murine model of breast cancer. Meeting [Details]
(2012) Relationship Between Circulating and Tissue MiRNAs in a Murine Model of Breast Cancer.
Waters, PS,Dwyer, RM,Wall, D,McDermott, AM,Newell, J,Kerin, MJ (2012) Relationship Between Circulating and Tissue MiRNAs in a Murine Model of Breast Cancer. Meeting [Details]
(2012) Evaluation of MicroRNA Secretion From Cancer Cells in Vitro.
Glynn, CL,Dwyer, RM,Khan, SJ,Kerin, MJ (2012) Evaluation of MicroRNA Secretion From Cancer Cells in Vitro. Meeting [Details]
(2012) Active Secretion of MicroRNAs and Plasminogen Activator Inhibitor-1 (PAI-1) by Colorectal Cancer Cells and Associated Stroma In Vitro.
Hogan, NM,Dwyer, RM,Glynn, CL,Joyce, MR,Kerin, MJ (2012) Active Secretion of MicroRNAs and Plasminogen Activator Inhibitor-1 (PAI-1) by Colorectal Cancer Cells and Associated Stroma In Vitro. Meeting [Details]
(2012) Active Secretion of MicroRNAs by Breast Cancer Cells.
Glynn, CL,Dwyer, RM,Khan, S,Kerin, MJ (2012) Active Secretion of MicroRNAs by Breast Cancer Cells. Meeting [Details]
(2013) Analysis of mir-339-5p expression and function in breast cancer.
Khan, S,Brougham, C,Wall, D,Curran, C,Newel, J,Kerin, MJ,Dwyer, RM (2013) Analysis of mir-339-5p expression and function in breast cancer. Meeting [Details]
(2013) Relationship between circulating miRNAs and breast cancer epithelial subtype.
Duignan, MF,Brougham, C,Waters, PS,Dwyer, RM,Kerin, MJ (2013) Relationship between circulating miRNAs and breast cancer epithelial subtype. Meeting [Details]
(2013) Identification and validation of a microrna signature associated with breast cancer progression.
Waters, PS,Dwyer, RM,Hyland, P,Brougham, C,Wall, D,Kerin, MJ (2013) Identification and validation of a microrna signature associated with breast cancer progression. Meeting [Details]
(2013) Interactions between mesenchymal stem cells (MSCs) and colorectal cancer cells are mediated by plasminogen activator inhibitor type 1 (PAI-1).
Hogan, NM,Dwyer, RM,Joyce, MR,Kerin, MJ (2013) Interactions between mesenchymal stem cells (MSCs) and colorectal cancer cells are mediated by plasminogen activator inhibitor type 1 (PAI-1). Meeting [Details]
(2013) Relationship between MicroRNA-379 and Cyclin-B1 in breast cancer.
O'Neill, GJ,Khan, S,Sahrudin, A,Kerin, M,Dwyer, R (2013) Relationship between MicroRNA-379 and Cyclin-B1 in breast cancer. Meeting [Details]
(2013) Mesenchymal stem cell secreted PAI-1 impacts on colon cancer cell migration and proliferation.
Hogan, NM,Dwyer, RM,Joyce, MR,Kerin, MJ (2013) Mesenchymal stem cell secreted PAI-1 impacts on colon cancer cell migration and proliferation. Meeting [Details]
(2013) Impact of tumour epithelial subtype on circulating microRNAs in breast cancer.
Brougham, CL,Waters, PS,Wall, D,Kerin, MJ,Dwyer, RM (2013) Impact of tumour epithelial subtype on circulating microRNAs in breast cancer. Meeting [Details]
(2013) Relationship between Circulating Micrornas and Breast Cancer Intrinsic Subtype.
Brougham, CL,Waters, PS,Wall, D,Dwyer, RM,Kerin, MJ (2013) Relationship between Circulating Micrornas and Breast Cancer Intrinsic Subtype. Meeting [Details]
(2013) Mir-339-5p Acts as A Tumour Suppressor in Breast Cancer, Mediated at Least in Part Through Regulation of Cell Proliferation.
Khan, S,Brougham, CL,Wall, D,Newell, J,Kerin, MJ,Dwyer, RM (2013) Mir-339-5p Acts as A Tumour Suppressor in Breast Cancer, Mediated at Least in Part Through Regulation of Cell Proliferation. Meeting [Details]
(2013) Role of Mesenchymal Stem Cells in the colorectal cancer cell environment: stimulation of Epithelial-Mesenchymal Transition.
Hogan, NM,Joyce, MR,Dwyer, RM,Kerin, MJ (2013) Role of Mesenchymal Stem Cells in the colorectal cancer cell environment: stimulation of Epithelial-Mesenchymal Transition. Meeting [Details]
(2013) Circulating and Tissue Levels of miR-504 in colorectal and breast cancer.
Hogan, N,Khan, S,Huong, QTT,Brogham, C,Joyce, MR,Kerin, MJ,Dwyer, RM (2013) Circulating and Tissue Levels of miR-504 in colorectal and breast cancer. Meeting [Details]
(2013) Elevated expression of miR-106 and miR-202 in breast cancer.
McLoughlin, M,Glynn, CL,Waters, PS,Khan, S,Dwyer, RM,Kerin, MJ (2013) Elevated expression of miR-106 and miR-202 in breast cancer. Meeting [Details]

Workshops

  Year Publication
(2006) Breast Cancer Cells Migrate in Response to Bone Marrow-Derived Mesenchymal Stem Cells (MSCs). Sir Peter Freyer Surgical Symposium.
RM Dwyer, FP Barry, T O'Brien and MJ Kerin. (2006) Breast Cancer Cells Migrate in Response to Bone Marrow-Derived Mesenchymal Stem Cells (MSCs). Sir Peter Freyer Surgical Symposium. Workshops [Details]
(2007) Novel Chemokines Induce Migration of Breast Cancer Cells Towards Bone Marrow-Derived Mesenchymal Stem Cells. Society of Academic & Research Surgery (SARS).
RM Dwyer, FP Barry, T O'Brien and MJ Kerin. (2007) Novel Chemokines Induce Migration of Breast Cancer Cells Towards Bone Marrow-Derived Mesenchymal Stem Cells. Society of Academic & Research Surgery (SARS). Workshops [Details]
(2007) The Role Of Primarry Stromal Cell-Derived Chemokines In The Breast Tumour Microenvironment. Nottingham International Breast Cancer Conference.
Dwyer, R. (2007) The Role Of Primarry Stromal Cell-Derived Chemokines In The Breast Tumour Microenvironment. Nottingham International Breast Cancer Conference. Workshops [Details]
(2007) Distinct Chemokines Mediate Tumourigenicity Of Breast Cancer Cells. Sir Peter Freyer Surgical Symposium.
Shirley Potter, Roisin Dwyer, and Michael Kerin. (2007) Distinct Chemokines Mediate Tumourigenicity Of Breast Cancer Cells. Sir Peter Freyer Surgical Symposium. Workshops [Details]
(2008) Role of Monocyte Chemotactic Protein-1 (MCP-1) in the Primary Breast Tumour Microenvironment. Sir Peter Freyer Surgical Symposium.
Shirley M Potter, Roisin M Dwyer, Michael J Kerin (2008) Role of Monocyte Chemotactic Protein-1 (MCP-1) in the Primary Breast Tumour Microenvironment. Sir Peter Freyer Surgical Symposium. Workshops [Details]
(2008) Elevated Plasma SDF-1 alpha Correlates with Tumour Grade. Society of Academic & Research Surgery (SARS).
Shirley Potter Beirne, Roisin Dwyer, Kate Harrington and Michael Kerin. (2008) Elevated Plasma SDF-1 alpha Correlates with Tumour Grade. Society of Academic & Research Surgery (SARS). Workshops [Details]

Honours and Awards

  Year Title Awarding Body
2013 BREAST-PREDICT Collaborative Cancer Research Centre Irish Cancer society
2012 Millenium Fund NUI Galway
2012 Irish Cancer Society Researcher of the Year Award Irish Cancer Society
2008 Research Project Grant Irish Cancer Society
2007 Research Project Grant Health Research Board
2005 National University of Ireland Postdoctroal Fellowship in the Sciences NUI

Professional Associations

  Association Function From / To
European Association for Cancer Research (EACR) Member 01-MAY-08 /
European Society for Gene and Cell Therapy (ESGCT) Member 01-AUG-09 /
American Association for Cancer Research (AACR) Member 01-NOV-08 /
Matrix Biology Ireland Council Member 01-FEB-16 /
American Society of Gene and Cell Therapy (ASGCT) Member 01-AUG-03 /

Committees

  Committee Function From / To
School of Medicine Research Committee Chairperson 01-FEB-17 /
College of Medicine Nursing and Health Sciences (CMNHS) Research Committee Committee Member 13-APR-16 /
College of Medicine Nursing and Health Sciences (CMNHS) Graduate Studies Committee Committee Member 10-MAR-16 /
School of Medicine Executive Committee Research Representative 23-FEB-16 /
School of Medicine Undergraduate Research Committee Chairperson 01-SEP-14 /

Employment

  Employer Position From / To
NUI Galway Lecturer in Translational Science 03-SEP-12 /
NUI Galway Research Fellow 01-NOV-05 / 31-AUG-12
Mayo Clinic Postdoctoral Scientist 01-APR-02 / 31-MAR-05

Education

  Year Institution Qualification Subject
1997 University College Dublin BSc (Hons) Science
2002 University College Dublin PhD Medicine
2015 NUI Galway MASTERS DEGREE (LEVEL 9) Academic Practice
1998 Dublin City University MASTERS OF SCIENCE Biological Sciences

Community Engagement

  Title Type From / To
Outreach Mini-Med School /
Outreach Youth Academy /
Outreach Pint of Science /

Recent Postgraduate Students

  Graduation Name Degree Primary Supervisor
2017 Doireann Joyce PhD Y
2012 Shirley Potter PhD Y
2010 John Kelly Y
2014 Claire Glynn PhD Y
2014 Sonja Khan PhD Y
2014 Peadar Waters Y
2009 Alan Molloy MASTERS DEGREE (LEVEL 9) Y
2014 Marion Hartmann PhD Y
2014 James Ryan PhD Y
2014 Niamh Hogan Y
2016 Cillian Clancy Y
2011 Fiachra Martin Y

Current Postgraduate Students (Research)

  Student Degree Type Type
Brian Moloney Doctorate - M.D. Degree Supervisor
Mary Mc Hale Doctorate - Ph.D. Supervisor
Killian O Brien Doctorate - Structured Ph.D (Medicine) Supervisor
Doireann Joyce Doctorate - Ph.D. Supervisor
Katie Gilligan Doctorate - Structured Ph.D (Medicine) Supervisor

Modules Taught

  Term/Year Module Title Module Code Subject / Desc
2013-date Surgical Lab Skills I MD560
2017/18 Imaging in Translational Cancer Research AN1504
2016-2017 Translational Science SSM GAL021

Internal Collaborators

  Name Description of Collaboration
Professor Timothy O'Brien
Professor Michael Kerin
Dr Linda Howard
Dr Mark Foley
Professor Martin Leahy

External Collaborators

  Name Organisation / Institute Country Description of Collaboration
Professor Harrison Barrett University of Arizona U.S.A.
Professor Zhonglin Liu University of Arizona U.S.A.
Professor John Morris Mayo Clinic, Rochester, Minnesota U.S.A.