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Medicine

Dr Róisín Dwyer

BSc, MSc, PhD

 
researcher
 

Biography

Dr Róisín Dwyer is Associate Professor in Translational Science and a PI in the Discipline of Surgery at NUI Galway.  Her research focuses on cell communication in the breast tumour microenvironment, with a view to harnessing this knowledge for development of novel gene therapy approaches for advanced breast cancer.
Tumours actively recruit stromal cells including Mesenchymal Stromal Cells (MSCs), and stromal-epithelial crosstalk plays a critical role in tumour development and progression. Dr Dwyer is interested in paracrine and autocrine mediators of this crosstalk, including chemokines/cytokines, microRNAs and extracellular vesicles (EVs). Understanding this environment will facilitate harnessing the potential of MSCs or their secreted EVs as vehicles for targeted delivery of therapy to breast tumours. In Vivo imaging to track MSC/EV migration is an important element of this.
Multidisciplinary collaboration is key to Dr Dwyer's work and she is a member of national and international research consortia, including Precision Oncology Ireland and the Celtic Advanced Life Science Innovation Network (CALIN). Her research has been recognised through a variety of honours including the inaugural Irish Cancer Society Researcher of the Year award. She has published >50 papers in respected journals such as Clinical Cancer Research, Molecular Therapy and Oncogene. She is a named inventor on patents, and works closely with industry collaborators to develop therapeutic EVs for a range of disease indications.
Along with a current team of 4 PhD students and one postdoctoral scientist, Dr Dwyer has supervised 10 PhD and 5MD students to completion, and mentored postdoctoral scientists and research assistants. Her team also hosts MSc students, and undergraduate research students annually. Dr Dwyer is actively involved in science outreach and routinely communicates research progress with patients, school children and the general public.

Research Interests

Róisín's current research, in collaboration with both national and international research groups, focuses on novel approaches to breast cancer therapy. Her work investigates the potential to engineer adult stem cells and secreted extracellular vesicles as vehicles for targeted delivery of therapeutic agents to breast tumours, with a specific interest in imaging modalities to track migration In Vivo. Other areas of interest include cellular interactions in the breast tumour microenvironment mediated by extracellular vesicles and microRNAs, and the potential to harness secreted factors as biomarkers of disease.

Research Projects

  Project Start Date End Date
Agreement with Omnispirant Ltd 01-JAN-20 31-MAR-21
lifETIME CENTRE FOR DOCTORAL TRAINING - ROISIN DWYER 01-AUG-19 31-JUL-27
COLLEGE OF MEDICINE WT BIOMEDICAL SUMMER VACATION SCHOLARSHIPS 2019 01-JUN-19 31-AUG-19
Róisín Dwyer - General Research Account 01-JAN-19 31-DEC-29
PILOT PRODUCTION OF GENETICALLY MODIFIED STEM CELL EXOSOMES FOR REGENERATIVE CYSTIC FIBROSIS GENE THERAPY AND; EVALUATION OF EXOSOMAL AEROSOL DELIVERY USING VIBRATING MESH TECHNOLOGY NEBULISATION. 11-SEP-18 10-SEP-20
MEDICINE HRB Summer Scholarships 2018 04-JUN-18 14-SEP-19
COLLEGE OF MEDICINE WT BIOMEDICAL SUMMER VACATION SCHOLARSHIPS 2018 01-JUN-18 31-AUG-18
IRC POSTGRADUATE SCHOLARSHIP 2016 KATIE GILLIGAN - Mesenchymal Stem Cell-mediated delivery of exosome-encapsulated microRNAs for the treatment of breast cancer 01-OCT-16 30-SEP-22
MESENCHYMAL ROISIN DWYER CRIO7DWY 01-APR-08 30-SEP-11

Peer Reviewed Journals

  Year Publication
(2021) 'Emerging Evidence of the Functional Impact of the miR379/miR656 Cluster (C14MC) in Breast Cancer'
McCarthy EC and Dwyer RM (2021) 'Emerging Evidence of the Functional Impact of the miR379/miR656 Cluster (C14MC) in Breast Cancer'. Biomedicines, 9 (7) [DOI] [Details]
(2021) 'Characterization of nanosensitive multifractality in submicron scale tissue morphology and its alteration in tumor progression'
Das N;Sergey A;Gilligan KE;Dwyer RM;Saager RB;Ghosh N;Leahy M; (2021) 'Characterization of nanosensitive multifractality in submicron scale tissue morphology and its alteration in tumor progression'. Journal Of Biomedical Optics, 26 (1) [DOI] [Details]
(2021) 'Boron clusters as breast cancer therapeutics'
Murphy N;McCarthy E;Dwyer R;Farràs P; (2021) 'Boron clusters as breast cancer therapeutics'. Journal Of Inorganic Biochemistry, 218 [DOI] [Details]
(2020) 'Targeting stromal cell Syndecan-2 reduces breast tumour growth, metastasis and limits immune evasion'
Loftus P;Watson L;Deedigan LM;Camarillo-Retamosa E;Dwyer RM;O'Flynn L;Griffin M;O'Brien T;Kerin M;Elliman SJ;Barkley LR; (2020) 'Targeting stromal cell Syndecan-2 reduces breast tumour growth, metastasis and limits immune evasion'. International Journal Of Cancer, [DOI] [Details]
(2020) 'Effect of Breast Cancer and Adjuvant Therapy on Adipose-Derived Stromal Cells: Implications for the Role of ADSCs in Regenerative Strategies for Breast Reconstruction'
Challapalli, RS,Dwyer, RM,McInerney, N,Kerin, MJ,Lowery, AJ (2020) 'Effect of Breast Cancer and Adjuvant Therapy on Adipose-Derived Stromal Cells: Implications for the Role of ADSCs in Regenerative Strategies for Breast Reconstruction'. Stem Cell Reviews And Reports, [DOI] [Details]
(2020) 'Nanoscale structure detection and monitoring of tumour growth with optical coherence tomography'
Das N, Sergey A, Zhou Y, Gilligan KE, Dwyer RM and Leahy M (2020) 'Nanoscale structure detection and monitoring of tumour growth with optical coherence tomography'. Nanoscale Advances, [Details]
(2020) 'Nanoparticle-Based Delivery of Tumor Suppressor microRNA for Cancer Therapy'
O'Neill CP;Dwyer RM; (2020) 'Nanoparticle-Based Delivery of Tumor Suppressor microRNA for Cancer Therapy'. Cells, 9 (2) [DOI] [Details]
(2020) 'Prospective Assessment of Systemic MicroRNAs as Markers of Response to Neoadjuvant Chemotherapy in Breast Cancer'
McGuire A;Casey MC;Waldron RM;Heneghan H;Kalinina O;Holian E;McDermott A;Lowery AJ;Newell J;Dwyer RM;Miller N;Keane M;Brown JAL;Kerin MJ; (2020) 'Prospective Assessment of Systemic MicroRNAs as Markers of Response to Neoadjuvant Chemotherapy in Breast Cancer'. Cancers, 12 (7) [DOI] [Details]
(2020) 'Extracellular Vesicles for Cancer Therapy: Impact of Host Immune Response'
Gilligan KE;Dwyer RM; (2020) 'Extracellular Vesicles for Cancer Therapy: Impact of Host Immune Response'. Cells, 9 (1) [DOI] [Details]
(2020) 'Investigating the Potential and Pitfalls of EV-Encapsulated MicroRNAs as Circulating Biomarkers of Breast Cancer'
Moloney BM;Gilligan KE;Joyce DP;O'Neill CP;O'Brien KP;Khan S;Glynn CL;Waldron RM;Maguire CM;Holian E;Naughton E;Elhadi M;Grealish AB;Malone C;McDermott E;Dockery P;Ritter T;Prina-Mello A;Kerin MJ;Dwyer RM; (2020) 'Investigating the Potential and Pitfalls of EV-Encapsulated MicroRNAs as Circulating Biomarkers of Breast Cancer'. Cells, 9 (1) [DOI] [Details]
(2019) 'Oncological Risk in Autologous Stem Cell Donation for Novel Tissue-Engineering Approaches to Postmastectomy Breast Regeneration'
O'Halloran, N,Khan, S,Gilligan, K,Dwyer, R,Kerin, M,Lowery, A (2019) 'Oncological Risk in Autologous Stem Cell Donation for Novel Tissue-Engineering Approaches to Postmastectomy Breast Regeneration'. Breast Cancer-Basic And Clinical Research, 13 [DOI] [Details]
(2019) 'Role of Extracellular Vesicles (EVs) in Cell Stress Response and Resistance to Cancer Therapy'
O’Neill CP, Gilligan KE and Dwyer RM (2019) 'Role of Extracellular Vesicles (EVs) in Cell Stress Response and Resistance to Cancer Therapy'. Cancers (Basel)Cancers (Basel), 11 (2) [DOI] [Details]
(2019) 'Relative and Absolute Expression Analysis of MicroRNAs Associated with Luminal A Breast Cancer- A Comparison'
Arabkari V;Clancy E;Dwyer RM;Kerin MJ;Kalinina O;Holian E;Newell J;Smith TJ; (2019) 'Relative and Absolute Expression Analysis of MicroRNAs Associated with Luminal A Breast Cancer- A Comparison'. Pathology oncology research : POR, [DOI] [Details]
(2018) 'Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy'
Logue SE, McGrath EP, Cleary P, Greene S, Mnich K, Almanza A, Chevet E, Dwyer RM, Oommen A, Legembre P, Godey F, Madden EC, Leuzzi B, Obacz J, Zeng Q, Patterson JB, Jäger R, Gorman AM, Samali A (2018) 'Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy'. Nature Communications, 9 [DOI] [Details]
(2019) 'Transcriptome Characterization of Matched Primary Breast and Brain Metastatic Tumors to Detect Novel Actionable Targets'
Varešlija D, Priedigkeit N, Fagan A, Purcell S, Cosgrove N, O'Halloran PJ, Ward E, Cocchiglia S, Hartmaier R, Castro CA, Zhu L, Tseng GC, Lucas PC, Puhalla SL, Brufsky AM, Hamilton RL, Mathew A, Leone JP, Basudan A, Hudson L, Dwyer R, Das S, O'Connor DP, Buckley PG, Farrell M, Hill ADK, Oesterreich S, Lee AV, Young LS. (2019) 'Transcriptome Characterization of Matched Primary Breast and Brain Metastatic Tumors to Detect Novel Actionable Targets'. Journal Of The National Cancer Institute, 111 (4):388-398 [DOI] [Details]
(2018) 'Employing mesenchymal stem cells to support tumor-targeted delivery of extracellular vesicle (EV)-encapsulated microRNA-379'
O'Brien, KP,Khan, S,Gilligan, KE,Zafar, H,Lalor, P,Glynn, C,O'Flatharta, C,Ingoldsby, H,Dockery, P,De Bhulbh, A,Schweber, JR,St John, K,Leahy, M,Murphy, JM,Gallagher, WM,O'Brien, T,Kerin, MJ,Dwyer, RM (2018) 'Employing mesenchymal stem cells to support tumor-targeted delivery of extracellular vesicle (EV)-encapsulated microRNA-379'. Oncogene, 37 :2137-2149 [DOI] [ARAN Link] [Details]
(2017) 'Engineering Exosomes for Cancer Therapy'
Gilligan KE, Dwyer RM. (2017) 'Engineering Exosomes for Cancer Therapy'. International Journal Of Molecular Sciences, 18 (6) [DOI] [Details]
(2017) 'Investigation of the effect of dehydration on tissue dielectric properties in ex vivo measurements'
Shahzad, A,Khan, S,Jones, M,Dwyer, RM,O'Halloran, M (2017) 'Investigation of the effect of dehydration on tissue dielectric properties in ex vivo measurements'. Biomedical Physics & Engineering Express, 3 [DOI] [Details]
(2017) 'S100 beta as a serum marker in endocrine resistant breast cancer'
Charmsaz, S;Hughes, E;Bane, FT;Tibbitts, P;McIlroy, M;Byrne, C;Cocchiglia, S;McBryan, J;Hennessy, BT;Dwyer, RM;Kerin, MJ;Hill, AD;Young, LS (2017) 'S100 beta as a serum marker in endocrine resistant breast cancer'. BMC medicine, 15 (1) [DOI] [Details]
(2017) 'Dual plasmonic gold nanostars for photoacoustic imaging and photothermal therapy'
Raghavan, V,O'Flatharta, C,Dwyer, R,Breathnach, A,Zafar, H,Dockery, P,Wheatley, A,Keogh, I,Leahy, M,Olivo, M (2017) 'Dual plasmonic gold nanostars for photoacoustic imaging and photothermal therapy'. Nanomedicine, 12 :457-471 [DOI] [Details]
(2017) 'Rapid Microarray Based Sandwich Assay for the Direct Detection of microRNAs'
Clancy E, Burke M, Arabkari V, Barry T, Kelly H, Dwyer RM, Kerin MJ. and Smith TJ (2017) 'Rapid Microarray Based Sandwich Assay for the Direct Detection of microRNAs'. Analytical And Bioanalytical Chemistry, 409 (14):3497-3505 [DOI] [Details]
(2016) 'Screening of exosomal microRNAs from colorectal cancer cells'
Clancy, C,Khan, S,Glynn, CL,Holian, E,Dockery, P,Lalor, P,Brown, JAL,Joyce, MR,Kerin, MJ,Dwyer, RM (2016) 'Screening of exosomal microRNAs from colorectal cancer cells'. Cancer Biomarkers, 17 :427-435 [DOI] [ARAN Link] [Details]
(2016) 'Exosome-encapsulated microRNAs as circulating biomarkers for breast cancer'
Joyce DP;Kerin MJ;Dwyer RM; (2016) 'Exosome-encapsulated microRNAs as circulating biomarkers for breast cancer'. International Journal Of Cancer, 139 (7):1443-1448 [DOI] [Details]
(2015) 'Cross Platform Standardisation of an Experimental Pipeline for Use in the Identification of Dysregulated Human Circulating MiRNAs'
Kelly, H,Downing, T,Tuite, NL,Smith, TJ,Kerin, MJ,Dwyer, RM,Clancy, E,Barry, T,Reddington, K (2015) 'Cross Platform Standardisation of an Experimental Pipeline for Use in the Identification of Dysregulated Human Circulating MiRNAs'. Plos One, 10 (9) [DOI] [Details]
(2015) 'MicroRNA-10a is reduced in breast cancer and regulated in part through retinoic acid'
Khan, S,Wall, D,Curran, C,Newell, J,Kerin, MJ,Dwyer, RM (2015) 'MicroRNA-10a is reduced in breast cancer and regulated in part through retinoic acid'. BMC Cancer, 15 (1) [DOI] [Details]
(2015) 'Solvent-selective routing for centrifugally automated solid-phase purification of RNA'
Dimov, N., Clancy, E., Gaughran, J., Boyle, D, McAuley, D., Glynn, M.T., Dwyer, R., Coughlan, H., Barry, T., Barrett, L.M., Smith, T.J. and Ducree, J. (2015) 'Solvent-selective routing for centrifugally automated solid-phase purification of RNA'. Microfluidics And Nanofluidics, 18 (5):859-871 [DOI] [ARAN Link] [Details]
(2014) 'Impact of Tumour Epithelial Subtype on Circulating microRNAs in Breast Cancer Patients'
Waters PS, Dwyer RM, Brougham C, Glynn CL, Wall D, Hyland P, Duignan M, McLoughlin M, Newell J, Kerin MJ (2014) 'Impact of Tumour Epithelial Subtype on Circulating microRNAs in Breast Cancer Patients'. Plos One, 9 (3) [DOI] [Details]
(2013) 'Objective assessment of image quality VI: imaging in radiation therapy'
Barrett, HH,Kupinski, MA,Mueller, S,Halpern, HJ,Morris, JC,Dwyer, R (2013) 'Objective assessment of image quality VI: imaging in radiation therapy'. Physics In Medicine And Biology, 58 :8197-8213 [DOI] [Details]
(2013) 'miR-379 Regulates Cyclin B1 Expression and Is Decreased in Breast Cancer'
Khan, S,Brougham, CL,Ryan, J,Sahrudin, A,O'Neill, G,Wall, D,Curran, C,Newell, J,Kerin, MJ,Dwyer, RM (2013) 'miR-379 Regulates Cyclin B1 Expression and Is Decreased in Breast Cancer'. Plos One, 8 (7) [DOI] [Details]
(2013) 'Design and performance of a small-animal imaging system using synthetic collimation'
Havelin RJ, Miller BW, Barrett HH, Furenlid LR, Murphy JM, Dwyer RM, Foley MJ (2013) 'Design and performance of a small-animal imaging system using synthetic collimation'. Physics In Medicine And Biology, 58 (10):3397-3412 [DOI] [ARAN Link] [Details]
(2013) 'Impact of Mesenchymal Stem Cell Secreted PAI-1 on Colon Cancer Cell Migration and Proliferation'
Hogan NM, Joyce MR, Murphy JM, Barry FP, O'Brien T, Kerin MJ, Dwyer RM (2013) 'Impact of Mesenchymal Stem Cell Secreted PAI-1 on Colon Cancer Cell Migration and Proliferation'. Biochem Biophy Res Commun, 435 :574-579 [DOI] [ARAN Link] [Details]
(2012) 'Influence of stromal-epithelial interactions on breast cancer in vitro and in vivo'
Potter, SM,Dwyer, RM,Hartmann, MC,Khan, S,Boyle, MP,Curran, CE,Kerin, MJ (2012) 'Influence of stromal-epithelial interactions on breast cancer in vitro and in vivo'. Breast Cancer Research And Treatment, 131 :401-411 [DOI] [ARAN Link] [Details]
(2012) 'Mesenchymal stem cells in the colorectal tumor microenvironment: Recent progress and implications'
Hogan, NM,Dwyer, RM,Joyce, MR,Kerin, MJ (2012) 'Mesenchymal stem cells in the colorectal tumor microenvironment: Recent progress and implications'. International Journal Of Cancer, 131 (1):1-7 [DOI] [ARAN Link] [Details]
(2012) 'Isolation of secreted microRNAs (miRNAs) from cell-conditioned media'
Glynn C, Khan S, Kerin MJ and Dwyer RM. (2012) 'Isolation of secreted microRNAs (miRNAs) from cell-conditioned media'. MicroRNA, 2 (1):14-19 [ARAN Link] [Details]
(2012) 'Relationship between Circulating and Tissue microRNAs in a Murine Model of Breast Cancer'
Waters, PS,McDermott, AM,Wall, D,Heneghan, HM,Miller, N,Newell, J,Kerin, MJ,Dwyer, RM (2012) 'Relationship between Circulating and Tissue microRNAs in a Murine Model of Breast Cancer'. Plos One, 7 (11) [DOI] [Details]
(2011) 'The Sodium Iodide Symporter (NIS) and Potential Regulators in Normal, Benign and Malignant Human Breast Tissue'
Ryan, J;Curran, CE;Hennessy, E;Newell, J;Morris, JC;Kerin, MJ;Dwyer, RM (2011) 'The Sodium Iodide Symporter (NIS) and Potential Regulators in Normal, Benign and Malignant Human Breast Tissue'. Plos One, 6 (1) [DOI] [Details]
(2011) 'Relationship between CCL5 and transforming growth factor-β1 (TGFβ1) in breast cancer'
Hartmann MC, Dwyer RM, Costello M, Potter SM, Curran C, Hennessy E, Newell J, Griffin DG, Kerin MJ (2011) 'Relationship between CCL5 and transforming growth factor-β1 (TGFβ1) in breast cancer'. European Journal Of Cancer, 47 (11):1669-1675 [DOI] [ARAN Link] [Details]
(2011) 'Mesenchymal Stem Cell-mediated delivery of the sodium iodide symporter supports radionuclide imaging and treatment of breast cancer'
Dwyer RM;Ryan J;Havelin RJ;Morris JC;Miller BW;Liu Z;Flavin R;O'Flatharta C;Foley MJ;Barrett HH;Murphy JM;Barry FP;O'Brien T;Kerin MJ; (2011) 'Mesenchymal Stem Cell-mediated delivery of the sodium iodide symporter supports radionuclide imaging and treatment of breast cancer'. Stem Cells (Dayton, Ohio), 29 (7):1149-1157 [DOI] [ARAN Link] [Details]
(2010) 'Potential role of mesenchymal stem cells (MSCs) in the breast tumour microenvironment: stimulation of epithelial to mesenchymal transition (EMT)'
Martin, FT;Dwyer, RM;Kelly, J;Khan, S;Murphy, JM;Curran, C;Miller, N;Hennessy, E;Dockery, P;Barry, FP;O'Brien, T;Kerin, MJ (2010) 'Potential role of mesenchymal stem cells (MSCs) in the breast tumour microenvironment: stimulation of epithelial to mesenchymal transition (EMT)'. Breast Cancer Research And Treatment, 124 (2):317-326 [DOI] [ARAN Link] [Details]
(2010) 'Advances in mesenchymal stem cell-mediated gene therapy for cancer'
Dwyer RM, Khan S, Barry FP, O'Brien T and Kerin MJ (2010) 'Advances in mesenchymal stem cell-mediated gene therapy for cancer'. Stem Cell Research And Therapy, 1 (3) [Details]
(2010) 'Mesenchymal Stem Cells (MSCs) and Cancer: tumour specific delivery vehicles or therapeutic targets?'
Dwyer RM Kerin MJ (2010) 'Mesenchymal Stem Cells (MSCs) and Cancer: tumour specific delivery vehicles or therapeutic targets?'. Human Gene Therapy, 21 (11):1506-1512 [ARAN Link] [Details]
(2010) 'Dysregulated miR-183 inhibits migration in breast cancer cells'
Lowery, AJ, Miller, N, Dwyer, RM, Kerin, MJ (2010) 'Dysregulated miR-183 inhibits migration in breast cancer cells'. BMC Cancer, 10 (1) [DOI] [Details]
(2009) 'Systemic chemokine levels in breast cancer patients and their relationship with circulating menstrual hormones'
Potter, SM,Dwyer, RM,Curran, CE,Hennessy, E,Harrington, KA,Griffin, DG,Kerin, MJ (2009) 'Systemic chemokine levels in breast cancer patients and their relationship with circulating menstrual hormones'. Breast Cancer Research And Treatment, 115 :279-287 [DOI] [ARAN Link] [Details]
(2009) 'Mesenchymal stem cell secretion of chemokines during differentiation into osteoblasts, and their potential role in mediating interactions with breast cancer cells'
Molloy, AP,Martin, FT,Dwyer, RM,Griffin, TP,Murphy, M,Barry, FP,O'Brien, T,Kerin, MJ (2009) 'Mesenchymal stem cell secretion of chemokines during differentiation into osteoblasts, and their potential role in mediating interactions with breast cancer cells'. International Journal Of Cancer, 124 :326-332 [DOI] [Details]
(2007) 'Monocyte Chemotactic Protein-1 (MCP-1) secreted by primary breast tumors stimulates migration of Mesenchymal Stem Cells (MSCs)'
Dwyer RM, Potter-Beirne SM, Harrington KA, Lowery AJ, Hennessy E, Murphy JM, Barry FP, O'Brien T, Kerin MJ (2007) 'Monocyte Chemotactic Protein-1 (MCP-1) secreted by primary breast tumors stimulates migration of Mesenchymal Stem Cells (MSCs)'. Clinical Cancer Research, 13 (17):5020-5027 [Details]
(2006) 'Sodium Iodide Symporter (NIS)-mediated Radioiodide Imaging and Therapy of Ovarian Tumor Xenografts in Mice'
Bergert ER, Gendler SJ, O'Connor MK and Morris JC (2006) 'Sodium Iodide Symporter (NIS)-mediated Radioiodide Imaging and Therapy of Ovarian Tumor Xenografts in Mice'. Gene Therapy, 13 (1):60-66 [Details]
(2006) 'Adenovirus-mediated and targeted expression of the sodium-iodide symporter permits in vivo radioiodide imaging and therapy of pancreatic tumors'
Bergert ER, Gendler SJ, O'Connor MK and Morris JC (2006) 'Adenovirus-mediated and targeted expression of the sodium-iodide symporter permits in vivo radioiodide imaging and therapy of pancreatic tumors'. Human Gene Therapy, 17 (6):661-668 [ARAN Link] [Details]
(2005) 'In Vivo Radioiodide Imaging and Treatment of Breast Cancer Xenografts Following MUC1-driven Expression of the Sodium Iodide Symporter (NIS)'
Bergert ER, Gendler SJ, O'Connor MK and Morris JC (2005) 'In Vivo Radioiodide Imaging and Treatment of Breast Cancer Xenografts Following MUC1-driven Expression of the Sodium Iodide Symporter (NIS)'. Cinical Cancer Research, 11 (4):1483-1489 [Details]
(2005) 'A Preclinical Large Animal Model of Adenovirus-Mediated Expression of the Sodium-Iodide Symporter for Radioiodide Imaging and Therapy of Locally Recurrent Prostate Cancer'
Schatz SM, Bergert ER, Myers RM, Harvey ME, Classic KL, Marler RJ, O'Connor MK and Morris JC (2005) 'A Preclinical Large Animal Model of Adenovirus-Mediated Expression of the Sodium-Iodide Symporter for Radioiodide Imaging and Therapy of Locally Recurrent Prostate Cancer'. Molecular Therapy, 12 (5):835-841 [Details]
(2002) 'The Sodium Iodide Symporter and Thyroid Disease'
Smyth PPA (2002) 'The Sodium Iodide Symporter and Thyroid Disease'. Clinical Endocrinology, 56 (4):427-429 [Details]
(2000) 'Tissue Iodine Content and Serum Mediated 125I Uptake Blocking Activity in Breast Cancer'
Kilbane MT, Ajjan RA, Weetman AP, Dwyer R, McDermott EWM, O'Higgins N J and Smyth PPA (2000) 'Tissue Iodine Content and Serum Mediated 125I Uptake Blocking Activity in Breast Cancer'. Journal of Clinical Endocrinology and Metabolism, 85 :1245-1250 [Details]

Book Chapters

  Year Publication
(2017) 'Circulating MicroRNAs in Cancer'
O'Brien KP, Ramphul E, Howard L, Gallagher WM, Malone C, Kerin MJ, Dwyer RM. (2017) 'Circulating MicroRNAs in Cancer' In: MicroRNA Profiling. :123-139 New York: Springer. [DOI] [ARAN Link] [Details]
(2013) 'Diagnostic and Therapeutic Mesenchymal stem cells for breast cancer treatment'
Dwyer RM (2013) 'Diagnostic and Therapeutic Mesenchymal stem cells for breast cancer treatment' In: Stem Cell based Therapeutics for Cancer. :145-158 Hoboken, NJ: John Wiley & Sons. [DOI] [ARAN Link] [Details]

Abstract

  Year Publication
(2015) Exosome-Mediated Intercellular Communication in The Breast Tumour Microenvironment.
Joyce, D,Khan, S,O'Brien, K,Kerin, MJ,Dwyer, R (2015) Exosome-Mediated Intercellular Communication in The Breast Tumour Microenvironment. Abstract [Details]
(2015) Analysis of Exosome-Encapsulated MicroRNAs Secreted by Mesenchymal Stem Cells in Vitro.
Clancy, C,Brougham, C,Joyce, MR,Dwyer, RM,Kerin, MJ (2015) Analysis of Exosome-Encapsulated MicroRNAs Secreted by Mesenchymal Stem Cells in Vitro. Abstract [Details]
(2015) Photoacoustic Imaging in Breast Cancer.
Casey, MC,Zafar, H,Ennis, R,Walsh, S,Brown, J,Malone, C,McLaughlin, R,Sweeney, K,Dwyer, R,Leahy, M,Kerin, MJ (2015) Photoacoustic Imaging in Breast Cancer. Abstract [Details]
(2015) Clinical Application of Circulating Micrornas As Biomarkers is Hindered by Lack of Standardised Protocols.
Brien, KO,Ramphul, E,Malone, C,Kerin, MJ,Dwyer, RM (2015) Clinical Application of Circulating Micrornas As Biomarkers is Hindered by Lack of Standardised Protocols. Abstract [Details]
(2014) Exosomal Transfer of Micrornas as a Potential Path for Gene Therapy.
Joyce, D,Glynn, C,Khan, S,Brown, J,Dockery, P,Kerin, M,Dwyer, R (2014) Exosomal Transfer of Micrornas as a Potential Path for Gene Therapy. Abstract [Details]
(2013) Investigation of miR-504 expression in colorectal and breast cancer.
Hogan, N,Khan, S,Huong, Q,Brogham, C,Joyce, MR,Kerin, MJ,Dwyer, RM (2013) Investigation of miR-504 expression in colorectal and breast cancer. Abstract [Details]
(2013) Exosome-Mediated Active Transport of Selected Micrornas by Breast Cancer Cells.
Glynn, C,Kerin, MJ,Dwyer, R (2013) Exosome-Mediated Active Transport of Selected Micrornas by Breast Cancer Cells. Abstract [Details]
(2012) Three-Dimensional Co-culture of Mesenchymal Stem Cells With Colorectal Cancer Cells in Vitro Has a Distinct Effect on Cytokine Secretion.
Hogan, N,Dwyer, RM,Joyce, MR,Kerin, MJ (2012) Three-Dimensional Co-culture of Mesenchymal Stem Cells With Colorectal Cancer Cells in Vitro Has a Distinct Effect on Cytokine Secretion. Abstract [Details]
(2012) Identification of a Tumour Suppressor MiRNA That Correlates With RAR beta Expression in Breast Cancer.
Khan, S,Ryan, J,Brougham, C,Wall, D,Newell, J,Kerin, MJ,Dwyer, RM (2012) Identification of a Tumour Suppressor MiRNA That Correlates With RAR beta Expression in Breast Cancer. Abstract [Details]
(2009) Correlation of Sodium Iodide Symporter (NIS) and Retinoic Acid Receptor Alpha (RARA) expression in breast cancer.
Ryan, J,Hennessy, E,Curran, C,Morris, JC,Kerin, MJ,Dwyer, RM (2009) Correlation of Sodium Iodide Symporter (NIS) and Retinoic Acid Receptor Alpha (RARA) expression in breast cancer. Abstract [Details]
(2015) Exosome-mediated trafficking of microRNAs by breast cancer cells.
Joyce, DP,Glynn, CL,Brown, J,Holian, E,Dockery, P,Kerin, MJ,Dwyer, RM (2015) Exosome-mediated trafficking of microRNAs by breast cancer cells. Abstract [Details]
(2015) Potential role of photoacoustic imaging in neoadjuvant chemotherapy response monitoring in breast cancer.
Casey, MC,Ennis, R,Walsh, S,Brown, JAL,Dwyer, RM,Leahy, MJ,Kerin, MJ (2015) Potential role of photoacoustic imaging in neoadjuvant chemotherapy response monitoring in breast cancer. Abstract [Details]
(2015) Investigation of exosome-encapsulated microRNAs as potential circulating biomarkers of breast cancer.
Joyce, DP,Higgins, M,Glynn, CL,Brown, J,Holian, E,Dockery, P,Kerin, MJ,Dwyer, RM (2015) Investigation of exosome-encapsulated microRNAs as potential circulating biomarkers of breast cancer. Abstract [Details]
(2015) Secretion of Exosome-Encapsulated MicroRNAs by Breast Cancer Cell Lines.
Joyce, D,Glynn, C,Dockery, P,Dwyer, R,Kerin, M (2015) Secretion of Exosome-Encapsulated MicroRNAs by Breast Cancer Cell Lines. Abstract [Details]
(2015) Investigating a tumour-suppressor role for miR-379 in colorectal cancer.
Clancy, C,Khan, S,Glynn, CL,Joyce, MR,Kerin, MJ,Dwyer, RM (2015) Investigating a tumour-suppressor role for miR-379 in colorectal cancer. Abstract [Details]
(2015) Exosome-mediated trafficking of microRNAs by basal breast cancer cells in vitro.
Joyce, DP,Glynn, CL,Higgins, M,Brown, J,Holian, E,Dockery, P,Kerin, MJ,Dwyer, RM (2015) Exosome-mediated trafficking of microRNAs by basal breast cancer cells in vitro. Abstract [Details]
(2014) Secretion of exosome-encapsulated oncomiRs by colorectal cancer cells in vitro.
Clancy, C,Joyce, MR,Kerin, MJ,Dwyer, RM (2014) Secretion of exosome-encapsulated oncomiRs by colorectal cancer cells in vitro. Abstract [Details]
(2014) Exosome-mediated active and selective secretion of MicroRNAs by breast cancer cells in vitro.
Rahmani, LS,Glynn, CL,Dwyer, RM,Kerin, MJ (2014) Exosome-mediated active and selective secretion of MicroRNAs by breast cancer cells in vitro. Abstract [Details]
(2014) Investigation of exosome-encapsulated microRNA secretion in breast cancer.
Glynn, C,Khan, S,Brougham, C,Clancy, C,Joyce, D,Dockery, P,Kerin, MJ,Dwyer, RM (2014) Investigation of exosome-encapsulated microRNA secretion in breast cancer. Abstract [DOI] [Details]
(2014) Exosome-Encapsulated MicroRNAs Secreted by Colorectal Cancer Cells: Mediators of Intercellular Cross-Talk in the Tumour Micro-Environment.
Clancy, C,Brown, J,Holian, E,Joyce, M,Kerin, MJ,Dwyer, RM (2014) Exosome-Encapsulated MicroRNAs Secreted by Colorectal Cancer Cells: Mediators of Intercellular Cross-Talk in the Tumour Micro-Environment. Abstract [Details]
(2014) Secretion of Exosome-Encapsulated MicroRNAs by Basal Breast Cancer Cells in Vitro.
Joyce, D,Glynn, C,Brown, J,Holian, E,Dockery, P,Kerin, MJ,Dwyer, R (2014) Secretion of Exosome-Encapsulated MicroRNAs by Basal Breast Cancer Cells in Vitro. Abstract [Details]
(2012) Identification and Validation of a MicroRNA Signature Associated with Breast Cancer Progression.
Waters, PS,Dwyer, RM,Wall, D,McDermott, AM,Newell, J,Kerin, MJ (2012) Identification and Validation of a MicroRNA Signature Associated with Breast Cancer Progression. Abstract [Details]
(2011) Mesenchymal Stem Cell (MSC) mediated delivery of the Sodium Iodide Symporter (NIS) supports radionuclide imaging and treatment of breast cancer. American Association for Cancer Research, Orlando, Florida.
Dwyer RM, Ryan J, Havelin RJ, Morris JC, O'Flatharta C, Miller BW, Liu Z, Foley MJ, Barrett HH, Murphy M, Barry FP, O'Brien T and Kerin MJ (2011) Mesenchymal Stem Cell (MSC) mediated delivery of the Sodium Iodide Symporter (NIS) supports radionuclide imaging and treatment of breast cancer. American Association for Cancer Research, Orlando, Florida. Abstract [Details]
(2010) CORRELATION BETWEEN CIRCULATING AND TUMOUR TISSUE CCL5 AND TGF beta 1 IN BREAST CANCER PATIENTS.
Hartmann, MC,Dwyer, RM,Costello, M,Kerin, MJ (2010) CORRELATION BETWEEN CIRCULATING AND TUMOUR TISSUE CCL5 AND TGF beta 1 IN BREAST CANCER PATIENTS. Abstract [Details]
(2009) EFFECT OF MONOCYTE CHEMOTACTIC PROTEIN-1(MCP-1) ON BREAST CANCER CELL PROLIFERATION AND GENE EXPRESSION.
Hartmann, MC,Dwyer, RM,Boyle, MP,Potter, SM,Kerin, MJ (2009) EFFECT OF MONOCYTE CHEMOTACTIC PROTEIN-1(MCP-1) ON BREAST CANCER CELL PROLIFERATION AND GENE EXPRESSION. Abstract [Details]
(2009) Analysis of Primary Breast Tumour Stromal Cells and Their Potential Role in Disease Progression.
Hartmann, MC,Dwyer, RM,Kerin, MJ (2009) Analysis of Primary Breast Tumour Stromal Cells and Their Potential Role in Disease Progression. Abstract [Details]
(2009) Mesenchymal Stem Cell (MSC) secretion of TGF beta and VEGF stimulates Epithelial to Mesenchymal Transition (EMT) in breast cancer cell lines.
Kelly, J,Dwyer, RM,Murphy, M,Barry, FP,O'Brien, T,Kerin, MJ (2009) Mesenchymal Stem Cell (MSC) secretion of TGF beta and VEGF stimulates Epithelial to Mesenchymal Transition (EMT) in breast cancer cell lines. Abstract [Details]
(2009) Characterization of primary tumour stromal cells and their potential role in the breast cancer microenvironment.
Hartmann, MC,Dwyer, RM,Potter, SM,Dockery, P,Kerin, MJ (2009) Characterization of primary tumour stromal cells and their potential role in the breast cancer microenvironment. Abstract [Details]
(2009) Potential promotion of metastatis of circulating breast cancer cells through interactions with mesenchymal stem cells (MSCs).
Martin, FT,Dwyer, RM,Murphy, MJ,Barry, FP,Brien, TO,Kerin, MJ (2009) Potential promotion of metastatis of circulating breast cancer cells through interactions with mesenchymal stem cells (MSCs). Abstract [Details]
(2009) Stromal-epithelial cell cross-talk in the breast tumour microenvironment elicits changes in tumour epithelial cell gene expression.
Potter, SM,Dwyer, RM,Kerin, MJ (2009) Stromal-epithelial cell cross-talk in the breast tumour microenvironment elicits changes in tumour epithelial cell gene expression. Abstract [Details]
(2008) Hormonal regulation of breast cancer associated chemokines.
Potter, S,Dwyer, RM,Hennessy, E,Griffin, DG,Kerin, MJ (2008) Hormonal regulation of breast cancer associated chemokines. Abstract [Details]
(2008) Investigation of the potential of mesenchymal stem cells (MSCs) for gene delivery to breast tumours.
Dwyer, RM,Morris, JC,Murphy, M,Barry, FP,O'Brien, T,Kenn, MJ (2008) Investigation of the potential of mesenchymal stem cells (MSCs) for gene delivery to breast tumours. Abstract [Details]
(2008) Elevated plasma sdf-1 alpha in breast cancer patients correlates with tumour grade.
Potter, S,Dwyer, R,Harrington, K,Kerin, M (2008) Elevated plasma sdf-1 alpha in breast cancer patients correlates with tumour grade. Abstract [Details]
(2008) Marrow-derived mesenchymal stem cells (MSCs) stimulate breast cancer cell secretion and expression of chemokines.
Martin, FT,Dwyer, RM,Murphy, JM,Barry, FP,O'Brien, T,Kerin, MJ (2008) Marrow-derived mesenchymal stem cells (MSCs) stimulate breast cancer cell secretion and expression of chemokines. Abstract [Details]
(2007) Myocardial Infarct-Produced Chemokine Stimulus Promotes Stem Cell Migration. Irish Society for Gene and Cell Therapy, Regenerative Medicine Institute (REMEDI), National University of Ireland, Galway, Ireland.
Kavanagh C, Sloane P, Dwyer R, Coleman CM, O'Brien T, Barry F (2007) Myocardial Infarct-Produced Chemokine Stimulus Promotes Stem Cell Migration. Irish Society for Gene and Cell Therapy, Regenerative Medicine Institute (REMEDI), National University of Ireland, Galway, Ireland. Abstract [Details]
(2007) Investigation of the potential of human mesenchymal stem cells (hMSC) as vectors for therapeutic gene delivery to breast tumours.
Dwyer, RM,Barry, FP,O'Brien, T,Kerin, MJ (2007) Investigation of the potential of human mesenchymal stem cells (hMSC) as vectors for therapeutic gene delivery to breast tumours. Abstract [Details]
(2007) The potential role of bone derived cells in the development of breast cancer metastases.
Molloy, AP,Dwyer, RM,Kerin, MJ (2007) The potential role of bone derived cells in the development of breast cancer metastases. Abstract [Details]
(2007) Myocardial Infarct-Produced Chemokine Stimulus Promotes Stem Cell Migration. Proceedings of the 5th International Society For Stem Cell Research.
Kavanagh C, Sloane P, Dwyer R, Coleman CM, O'Brien T, Barry F (2007) Myocardial Infarct-Produced Chemokine Stimulus Promotes Stem Cell Migration. Proceedings of the 5th International Society For Stem Cell Research. Cairns, Australia: Abstract [Details]
(2007) Osteoblasts and their progenitors stimulate breast cancer cell migration through chemokine secretion.
Molloy, AP,Dwyer, RM,Kerin, MJ (2007) Osteoblasts and their progenitors stimulate breast cancer cell migration through chemokine secretion. Abstract [Details]
(2007) Distinct chemokines mediate tumourigenicity of breast cancer cells.
Potter, SM,Dwyer, RM,Kerin, MJ (2007) Distinct chemokines mediate tumourigenicity of breast cancer cells. Abstract [Details]

ANET/COS

  Year Publication
(2009) European Journal of Cancer Supplements 7 (2), 89.
Kelly, J,Dwyer, RM,Murphy, M,Barry, FP,O'Brien, T,Kerin, MJ (2009) European Journal of Cancer Supplements 7 (2), 89. ANET/COS [Details]
(2009) Orthopedics.
Molloy AP, Martin FT, Dwyer RM, Griffin TP, Murphy M, Barry FP, O'Brien T, Kerin MJ. (2009) Orthopedics. ANET/COS [DOI] [Details]
(2008) European Journal of Cancer Supplements 6 (9).
Dwyer, RM,Morris, JC,Murphy, M,Barry, FP,O'Brien, T,Kerin, MJ (2008) European Journal of Cancer Supplements 6 (9). ANET/COS [Details]

Book Review

  Year Publication
(2016) An evaluation of multiple novel markers expression on breast cancer recurrence and outcome.
Cuggy, C,Elwahab, SA,Khan, S,Dwyer, RM,Sweeney, KJ,McLaughlin, R,Kerins, MJ,Malone, C (2016) An evaluation of multiple novel markers expression on breast cancer recurrence and outcome. Book Review [Details]

Conference Paper

  Year Publication
(2011) Cellular Interactions in the Primary Tumour Microenvironment. Sir Peter Freyer Surgical Symposium.
Sonja Khan, Roisin M Dwyer, Karl J Sweeney and Michael J Kerin (2011) Cellular Interactions in the Primary Tumour Microenvironment. Sir Peter Freyer Surgical Symposium. Galway, Ireland Conference Paper [Details]
(2010) Potential role for thyroid hormones in regulation of mammary Sodium Iodide Symporter expression. Sir Peter Freyer Surgical Symposium.
J. Ryan, C.C. Curran, E. Hennessy, J.C. Morris, M.J. Kerin and R.M. Dwyer (2010) Potential role for thyroid hormones in regulation of mammary Sodium Iodide Symporter expression. Sir Peter Freyer Surgical Symposium. Galway, Ireland Conference Paper [Details]
(2010) Breast Tumour Stromal-Epithelial Interactions Stimulate Increased VEGF Secretion And Angiogenesis In Vitro and In Vivo.. Sir Peter Freyer Surgical Symposium.
S Khan, RM Dwyer, SM Potter and MJ Kerin (2010) Breast Tumour Stromal-Epithelial Interactions Stimulate Increased VEGF Secretion And Angiogenesis In Vitro and In Vivo.. Sir Peter Freyer Surgical Symposium. Galway, Ireland Conference Paper [Details]
(2010) Potential of circulating chemokines as serum tumour markers in breast cancer. Society of Academic & Research Surgery (SARS).
Costello M, Hartmann MC, Dwyer RM, Kerin MJ (2010) Potential of circulating chemokines as serum tumour markers in breast cancer. Society of Academic & Research Surgery (SARS). London, UK Conference Paper [Details]
(2010) Correlation between circulating and tumour tissue CCL5 and TGFß1 in breast cancer patients. Sir Peter Freyer Surgical Symposium.
Hartmann MC, Dwyer RM, Costello M, Kerin MJ (2010) Correlation between circulating and tumour tissue CCL5 and TGFß1 in breast cancer patients. Sir Peter Freyer Surgical Symposium. Galway, Ireland Conference Paper [Details]
(2010) Investigation of potential role of CCL5 in breast cancer progression. Sylvester O Halloran Surgical Symposium.
Hartmann MC, Dwyer RM, Costello M, Kerin MJ (2010) Investigation of potential role of CCL5 in breast cancer progression. Sylvester O Halloran Surgical Symposium. Limerick, Ireland Conference Paper [Details]
(2009) Mesenchymal Stem Cells (MSCs) may promote breast cancer metastatic potential through stimulation of Epithelial-Mesenchymal Transition (EMT). Society of Academic & Research Surgery (SARS).
FT Martin, RM Dwyer, JM Murphy, N Miller, FP Barry, T O'Brien and MJ Kerin (2009) Mesenchymal Stem Cells (MSCs) may promote breast cancer metastatic potential through stimulation of Epithelial-Mesenchymal Transition (EMT). Society of Academic & Research Surgery (SARS). Bristol, UK Conference Paper [Details]
(2009) Expression of the sodium iodide symporter in breast cancer. Sir Peter Freyer Surgical Symposium.
J. Ryan, E. Hennessey, C.C. Curran, J.C. Morris, M.J. Kerin and R.M. Dwyer (2009) Expression of the sodium iodide symporter in breast cancer. Sir Peter Freyer Surgical Symposium. Galway, Ireland Conference Paper [Details]
(2009) Mesenchymal stem cells and breast cancer: therapeutic delivery vehicles or tumour promoting agents. Sir Peter Freyer Surgical Symposium.
John C Kelly, Roisin M. Dwyer, Mary Murphy, Frank P Barry, Timothy O'Brien and Michael J. Kerin (2009) Mesenchymal stem cells and breast cancer: therapeutic delivery vehicles or tumour promoting agents. Sir Peter Freyer Surgical Symposium. Galway, Ireland Conference Paper [Details]
(2009) Paracrine impact of Mesenchymal Stem Cells (MSCs) on breast cancer cell gene expression. Sylvester O Halloran Surgical Symposium.
John C Kelly, Roisin M. Dwyer, Fiachra T Martin, Mary Murphy, Frank P Barry, Timothy O'Brien and Michael J. Kerin (2009) Paracrine impact of Mesenchymal Stem Cells (MSCs) on breast cancer cell gene expression. Sylvester O Halloran Surgical Symposium. Limerick, Ireland Conference Paper [Details]
(2009) TUMOUR PROMOTING ROLE OF PRIMARY STROMAL CELLS IN THE BREAST CANCER MICROENVIRONMENT IN VIVO AND IN VITRO. Irish Association for Cancer Research (IACR).
Shirley M Potter, Roisin M Dwyer, Marie P Boyle, Marion C Hartmann, Catherine E Curran, Emer Hennessy and Michael J Kerin. (2009) TUMOUR PROMOTING ROLE OF PRIMARY STROMAL CELLS IN THE BREAST CANCER MICROENVIRONMENT IN VIVO AND IN VITRO. Irish Association for Cancer Research (IACR). Athlone, Ireland Conference Paper [Details]
(2009) Potential role of Monocyte Chemotactic Protein-1 (MCP-1) in the Breast Cancer Microenvironment. Sylvester O Halloran Surgical Symposium.
M.C. Hartmann, R.M. Dwyer, M.P. Boyle, S.M. Potter and M.J. Kerin (2009) Potential role of Monocyte Chemotactic Protein-1 (MCP-1) in the Breast Cancer Microenvironment. Sylvester O Halloran Surgical Symposium. Limerick, Ireland Conference Paper [Details]
(2009) Potential promotion of metastatis of circulating breast cancer cells through interactions with mesenchymal stem cells (MSCs). CANCER RESEARCH.
Martin, FT,Dwyer, RM,Murphy, MJ,Barry, FP,Brien, TO,Kerin, MJ (2009) Potential promotion of metastatis of circulating breast cancer cells through interactions with mesenchymal stem cells (MSCs). CANCER RESEARCH. AMER ASSOC CANCER RESEARCH 615 CHESTNUT ST, 17TH FLOOR, PHILADELPHIA, PA 19106-4404 USAAMER ASSOC CA Conference Paper [Details]
(2009) Sodium iodide symporter (NIS) mediated tracking of mesenchymal stem cell (MSC) migration to breast tumours in vivo. European Society for Gene and Cell Therapy (ESGCT).
Dwyer R, Ryan J, Havelin R, Morris J, O'Flatharta C, Duffy G, Miller B, Liu ZL, Barrett H, Murphy M, Barry F, O'Brien T, Kerin M (2009) Sodium iodide symporter (NIS) mediated tracking of mesenchymal stem cell (MSC) migration to breast tumours in vivo. European Society for Gene and Cell Therapy (ESGCT). Hannover, Germany Conference Paper [Details]
(2009) Interactions between Mesenchymal Stem Cells (MSCs) and Breast Cancer Cells support induction of Epithelial - Mesenchymal Transition (EMT). Irish Association for Cancer Research (IACR).
FT Martin, RM Dwyer, J Kelly, JM Murphy, N Miller, E Hennessy, C Curran, FP Barry, T O'Brien, MJ Kerin (2009) Interactions between Mesenchymal Stem Cells (MSCs) and Breast Cancer Cells support induction of Epithelial - Mesenchymal Transition (EMT). Irish Association for Cancer Research (IACR). Athlone, Ireland Conference Paper [Details]
(2009) Characterisation of primary tumour stromal cells and their role in the breast tumour microenvironment. Sir Peter Freyer Surgical Symposium.
M.C. Hartmann, R.M. Dwyer, S.M. Potter, M.P. Boyle and M.J. Kerin. (2009) Characterisation of primary tumour stromal cells and their role in the breast tumour microenvironment. Sir Peter Freyer Surgical Symposium. Galway, Ireland Conference Paper [Details]
(2008) Marrow-Derived Mesenchymal Stem Cells (MSCs) stimulate chemokine secretion and alter gene expression in breast cancer cells. Association of Surgeons of Great Britain and Ireland (ASGBI).
FT Martin, RM Dwyer, TP Griffin, JM Murphy, FP Barry, T O'Brien and MJ Kerin (2008) Marrow-Derived Mesenchymal Stem Cells (MSCs) stimulate chemokine secretion and alter gene expression in breast cancer cells. Association of Surgeons of Great Britain and Ireland (ASGBI). Bournemouth, UK Conference Paper [Details]
(2008) The Role of Bone-Derived Mesenchymal Stem Cells (MSCs) in Facilitating Breast Cancer Metastasis. Sylvester O Halloran Surgical Symposium.
FT Martin, RM Dwyer, TP Griffin, JM Murphy, FP Barry, T O'Brien and MJ Kerin (2008) The Role of Bone-Derived Mesenchymal Stem Cells (MSCs) in Facilitating Breast Cancer Metastasis. Sylvester O Halloran Surgical Symposium. Limerick, Ireland Conference Paper [Details]
(2007) Investigation of the Potential of Human Mesenchymal Stem Cells (hMSC) as Vectors for Therapeutic Gene Delivery to Breast Tumours. Irish Society for Gene and Cell Therapy (ISGCT).
RM Dwyer, FP Barry, T O'Brien and MJ Kerin. (2007) Investigation of the Potential of Human Mesenchymal Stem Cells (hMSC) as Vectors for Therapeutic Gene Delivery to Breast Tumours. Irish Society for Gene and Cell Therapy (ISGCT). Galway, Ireland Conference Paper [Details]
(2007) The role of Chemokine production by Primary Breast Cancer Stromal Cells in tumour progression.. Association of Surgeons of Great Britain and Ireland (ASGBI).
Shirley M Potter-Beirne, Roisin M Dwyer, Micheal J Kerin (2007) The role of Chemokine production by Primary Breast Cancer Stromal Cells in tumour progression.. Association of Surgeons of Great Britain and Ireland (ASGBI). Manchester, UK Conference Paper [Details]
(2007) Mesenchymal Stem Cells (MSCs) as Potential Vectors for Delivery of Therapeutic Agents to Breast Tumours. NBCRI/NCBES Breast Cancer Research Day.
RM Dwyer, FP Barry, T O'Brien and MJ Kerin. (2007) Mesenchymal Stem Cells (MSCs) as Potential Vectors for Delivery of Therapeutic Agents to Breast Tumours. NBCRI/NCBES Breast Cancer Research Day. Galway, Ireland Conference Paper [Details]
(2007) The potential role of bone-derived cells in development of breast cancer metastases. Sir Peter Freyer Surgical Symposium.
AP Molloy, RM Dwyer and MJ Kerin (2007) The potential role of bone-derived cells in development of breast cancer metastases. Sir Peter Freyer Surgical Symposium. Galway, Ireland Conference Paper [Details]

Conference Poster

  Year Publication
(2011) Mesenchymal Stem Cell (MSC) mediated delivery of the Sodium Iodide Symporter (NIS) supports radionuclide imaging and treatment of breast cancer. American Association for Cancer Research (AACR).
Roisin M. Dwyer, James Ryan, Ronan Havelin, John C. Morris, Cathal O'Flatharta, Brian Miller, Zhonglin Liu, Mark Foley, Harrison H. Barrett, Mary Murphy, Frank P. Barry, Timothy O'Brien and Michael J. Kerin. (2011) Mesenchymal Stem Cell (MSC) mediated delivery of the Sodium Iodide Symporter (NIS) supports radionuclide imaging and treatment of breast cancer. American Association for Cancer Research (AACR). Orlando Florida, USA Conference Poster [Details]
(2010) Potential Role of Primary Breast Cancer Stromal Cells in the Development of Endocrine Resistance. Irish Association for Cancer Research (IACR).
S Khan, RM Dwyer, MC Hartmann and MJ Kerin (2010) Potential Role of Primary Breast Cancer Stromal Cells in the Development of Endocrine Resistance. Irish Association for Cancer Research (IACR). Galway, Ireland Conference Poster [Details]
(2010) Expression of the Sodium Iodide Symporter and potential regulators in Normal, Benign and Malignant breast tissue. Irish Association for Cancer Research (IACR).
J. Ryan, C.C. Curran, E. Hennessy, J.C. Morris, M.J. Kerin and R.M. Dwyer (2010) Expression of the Sodium Iodide Symporter and potential regulators in Normal, Benign and Malignant breast tissue. Irish Association for Cancer Research (IACR). Galway, Ireland Conference Poster [Details]
(2010) Circulating and tumour tissue levels of CCL5/RANTES in breast cancer. Irish Association for Cancer Research (IACR).
Hartmann MC, Dwyer RM, Costello M, Kerin MJ (2010) Circulating and tumour tissue levels of CCL5/RANTES in breast cancer. Irish Association for Cancer Research (IACR). Galway, Ireland Conference Poster [Details]
(2010) CCL5 in Breast Cancer: Circulating systemic levels and gene expression in the primary tumour microenvironment. American Association for Cancer Research (AACR).
Hartmann MC, Dwyer RM, Costello M, Kerin MJ (2010) CCL5 in Breast Cancer: Circulating systemic levels and gene expression in the primary tumour microenvironment. American Association for Cancer Research (AACR). Washington DC, USA Conference Poster [Details]
(2009) Effect of Monocyte Chemotactic Protein-1 (MCP-1) on breast cancer cell proliferation and gene expression. Targeted AntiCancer Therapies (TAT), , 23rd-25th March 2009.
Marion C Hartmann, Roisin M Dwyer, Marie P Boyle, Shirley M Potter and Prof Michael J Kerin (2009) Effect of Monocyte Chemotactic Protein-1 (MCP-1) on breast cancer cell proliferation and gene expression. Targeted AntiCancer Therapies (TAT), , 23rd-25th March 2009. Amsterdam Conference Poster [Details]
(2009) Potential Role of Mesenchymal Stem Cells (MSCs) in the Breast Tumour Microenvironment: Stimulation of Epithelial to Mesenchymal Transition (EMT). American Association for Cancer Research (AACR).
FT Martin, RM Dwyer, JM Murphy, N Miller, FP Barry, T O'Brien and MJ Kerin (2009) Potential Role of Mesenchymal Stem Cells (MSCs) in the Breast Tumour Microenvironment: Stimulation of Epithelial to Mesenchymal Transition (EMT). American Association for Cancer Research (AACR). Denver Colorado Conference Poster [Details]
(2009) Analysis of primary breast tumour stromal cells and their potential role in disease progression. San Antonio Breast Cancer Symposium.
M.C. Hartmann, R.M. Dwyer and M.J. Kerin (2009) Analysis of primary breast tumour stromal cells and their potential role in disease progression. San Antonio Breast Cancer Symposium. San Antonio, Texas, USA Conference Poster [Details]
(2009) Role of Stromal-Epithelial interactions in the primary breast tumour microenvironment in vitro and in vivo. American Association for Cancer Research (AACR).
Shirley M Potter, Roisin M Dwyer, Marie P Boyle, Marion C Hartmann, Catherine E Curran, Emer Hennessy and Michael J Kerin. (2009) Role of Stromal-Epithelial interactions in the primary breast tumour microenvironment in vitro and in vivo. American Association for Cancer Research (AACR). Denver Colorado Conference Poster [Details]
(2009) Correlation of Sodium Iodide Symporter (NIS) and Retinoic Acid Receptor Alpha (RARA) expression in breast cancer. European Cancer Organisation (ECCO)/ESMO.
J. Ryan, E. Hennessy, C.C. Curran, J.C. Morris, M.J. Kerin and R.M. Dwyer (2009) Correlation of Sodium Iodide Symporter (NIS) and Retinoic Acid Receptor Alpha (RARA) expression in breast cancer. European Cancer Organisation (ECCO)/ESMO. Berlin, Germany Conference Poster [Details]
(2009) Mesenchymal Stem Cell (MSC) secretion of TGFb and VEGF stimulates Epithelial to Mesenchymal Transition (EMT) in breast cancer cell lines. European Cancer Organisation (ECCO)/ESMO.
John C Kelly, Roisin M. Dwyer, Mary Murphy, Frank P Barry, Timothy O'Brien and Michael J. Kerin (2009) Mesenchymal Stem Cell (MSC) secretion of TGFb and VEGF stimulates Epithelial to Mesenchymal Transition (EMT) in breast cancer cell lines. European Cancer Organisation (ECCO)/ESMO. Berlin, Germany Conference Poster [Details]
(2009) Characterization of primary tumour stromal cells and their potential role in the breast cancer microenvironment. European Cancer Organisation (ECCO)/ESMO.
M.C. Hartmann, R.M. Dwyer, S.M. Potter, P Dockery and M.J. Kerin. (2009) Characterization of primary tumour stromal cells and their potential role in the breast cancer microenvironment. European Cancer Organisation (ECCO)/ESMO. Berlin, Germany Conference Poster [Details]
(2009) DISTINCT PROPERTIES OF BREAST TUMOUR COMPARED TO NORMAL STROMAL CELLS AND THEIR INFLUENCE ON BREAST CANCER EPITHELIAL CELL GENE EXPRESSION. Society of Academic & Research Surgery (SARS).
Shirley M Potter, Marie P Boyle, Roisin M Dwyer, Nicola Miller and Micheal J Kerin. (2009) DISTINCT PROPERTIES OF BREAST TUMOUR COMPARED TO NORMAL STROMAL CELLS AND THEIR INFLUENCE ON BREAST CANCER EPITHELIAL CELL GENE EXPRESSION. Society of Academic & Research Surgery (SARS). Bristol, UK Conference Poster [Details]
(2008) Stromal-epithalial cell Cross-talk In The Breast Tumour Microenvironment Elicits Changes In Gene Expression in Breast Cancer Epithelial Cells. San Antonio Breast Cancer Symposium.
Shirley M Potter, Roisin M Dwyer, Michael J Kerin (2008) Stromal-epithalial cell Cross-talk In The Breast Tumour Microenvironment Elicits Changes In Gene Expression in Breast Cancer Epithelial Cells. San Antonio Breast Cancer Symposium. San Antonio, Texas, USA Conference Poster [Details]
(2008) Potential promotion of the metastatic potential of circulating Breast Cancer Cells through interactions with Mesenchymal Stem Cells (MSCs). San Antonio Breast Cancer Symposium.
FT Martin, RM Dwyer, JM Murphy, FP Barry, T O'Brien and MJ Kerin (2008) Potential promotion of the metastatic potential of circulating Breast Cancer Cells through interactions with Mesenchymal Stem Cells (MSCs). San Antonio Breast Cancer Symposium. San Antonio, Texas, USA Conference Poster [Details]
(2008) Hormonal regulation of breast cancer associated chemokines. European Association for Cancer Research (EACR).
Shirley M. Potter, Roisin M. Dwyer, Emer Hennessy, Damien Griffin and Michael J. Kerin. (2008) Hormonal regulation of breast cancer associated chemokines. European Association for Cancer Research (EACR). Lyon, France Conference Poster [Details]
(2008) Sodium Iodide Symporter (NIS) mediated Iodide Uptake in Mesenchymal Stem Cells following Adenoviral Transduction. American Society of Gene Therapy (ASGT).
RM Dwyer, JC Morris, JM Murphy, FP Barry, T O'Brien and MJ Kerin. (2008) Sodium Iodide Symporter (NIS) mediated Iodide Uptake in Mesenchymal Stem Cells following Adenoviral Transduction. American Society of Gene Therapy (ASGT). Boston, Massacheusetts, USA Conference Poster [Details]
(2008) Next Generation Mesenchymal Stem Cells for Regenerative Medicine Applications: Antibodies, Peptides and Lipoplexes for isolation, expansion and genetic modification of MSCs from several species. Irish Society for Gene and Cell Therapy (ISGCT).
Udo Greiser, Melissa Hoare, Tyrone Bowes, Roisin Dwyer, Daniel O'Toole, Kaveh Mashayekhi, Mary Murphy, Frank Barry and Timothy O'Brien (2008) Next Generation Mesenchymal Stem Cells for Regenerative Medicine Applications: Antibodies, Peptides and Lipoplexes for isolation, expansion and genetic modification of MSCs from several species. Irish Society for Gene and Cell Therapy (ISGCT). Cork, Ireland Conference Poster [Details]
(2008) Circulating Stromal Cell Derived Factor-1a (SDF-1a) in Premenopausal Women is Influenced by Phase of Menstrual Cycle. Association of Surgeons of Great Britain and Ireland (ASGBI).
Shirley M. Potter, Roisin M. Dwyer, Emer Hennessy, Damien Griffin and Michael J. Kerin. (2008) Circulating Stromal Cell Derived Factor-1a (SDF-1a) in Premenopausal Women is Influenced by Phase of Menstrual Cycle. Association of Surgeons of Great Britain and Ireland (ASGBI). Bournemouth, UK Conference Poster [Details]
(2008) Circulating Stromal Cell Derived Factor-1a (SDF-1a) in Premenopausal Women is Influenced by Phase of Menstrual Cycle. Sir Peter Freyer Surgical Symposium.
Shirley M. Potter, Roisin M. Dwyer, Emer Hennessy, Damian G. Griffin and Michael J. Kerin. (2008) Circulating Stromal Cell Derived Factor-1a (SDF-1a) in Premenopausal Women is Influenced by Phase of Menstrual Cycle. Sir Peter Freyer Surgical Symposium. Galway, Ireland Conference Poster [Details]
(2008) Investigation of the potential of Mesenchymal Stem Cells (MSCs) for gene delivery to breast tumours. European Association for Cancer Research (EACR).
RM Dwyer, JC Morris, JM Murphy, FP Barry, T O'Brien and MJ Kerin. (2008) Investigation of the potential of Mesenchymal Stem Cells (MSCs) for gene delivery to breast tumours. European Association for Cancer Research (EACR). Lyon, France Conference Poster [Details]
(2008) Marrow-Derived Mesenchymal Stem Cells (MSCs) stimulate chemokine secretion and gene expression in breast cancer cells. European Association for Cancer Research (EACR).
FT Martin, RM Dwyer, TP Griffin, JM Murphy, FP Barry, T O'Brien and MJ Kerin (2008) Marrow-Derived Mesenchymal Stem Cells (MSCs) stimulate chemokine secretion and gene expression in breast cancer cells. European Association for Cancer Research (EACR). Lyon, France Conference Poster [Details]
(2008) Sodium Iodide Symporter (NIS) mediated Iodide Uptake in Mesenchymal Stem Cells following Adenoviral Transduction. Irish Society for Gene and Cell Therapy (ISGCT).
RM Dwyer, JC Morris, JM Murphy, FP Barry, T O'Brien and MJ Kerin. (2008) Sodium Iodide Symporter (NIS) mediated Iodide Uptake in Mesenchymal Stem Cells following Adenoviral Transduction. Irish Society for Gene and Cell Therapy (ISGCT). Cork, Ireland Conference Poster [Details]
(2007) Role of Osteoblasts in Promoting Breast Cancer Cell Migration and Proliferation. Irish Association for Cancer Research.
AP Molloy, RM Dwyer, MJ Kerin (2007) Role of Osteoblasts in Promoting Breast Cancer Cell Migration and Proliferation. Irish Association for Cancer Research. Cork, Ireland Conference Poster [Details]
(2007) Analysis of the role of osteogenic cells in breast cancer metastasis. Association of Surgeons of Great Britain and Ireland (ASGBI).
AP Molloy, RM Dwyer, MJ Kerin (2007) Analysis of the role of osteogenic cells in breast cancer metastasis. Association of Surgeons of Great Britain and Ireland (ASGBI). Manchester, UK Conference Poster [Details]
(2007) The Role of Primary Stromal Cell-derived Chemokines in the Breast Tumour Microenvironment. European Cancer Organisation (ECCO).
Shirley M Potter-Beirne, Roisin M Dwyer and Michael J Kerin (2007) The Role of Primary Stromal Cell-derived Chemokines in the Breast Tumour Microenvironment. European Cancer Organisation (ECCO). Barcelona, Spain Conference Poster [Details]
(2007) Osteoblasts and their progenitors stimulate breast cancer cell migration through chemokine secretion. San Antonio Breast Cancer Symposium.
Molloy AP, Dwyer RM, Kerin MJ. (2007) Osteoblasts and their progenitors stimulate breast cancer cell migration through chemokine secretion. San Antonio Breast Cancer Symposium. San Antonio, Texas, USA Conference Poster [Details]
(2007) Distinct Chemokines Mediate Tumourigenicity of Breast Cancer Cells. San Antonio Breast Cancer Symposium.
Shirley Potter Beirne, Roisin Dwyer, and Michael Kerin. (2007) Distinct Chemokines Mediate Tumourigenicity of Breast Cancer Cells. San Antonio Breast Cancer Symposium. San Antonio, Texas, USA Conference Poster [Details]
(2007) The potential role of bone derived cells in the development of breast cancer metastases. European Cancer Organisation (ECCO).
AP Molloy, RM Dwyer, MJ Kerin (2007) The potential role of bone derived cells in the development of breast cancer metastases. European Cancer Organisation (ECCO). Barcelona, Spain Conference Poster [Details]
(2007) Investigation of the potential of human Mesenchymal Stem Cells (hMSC) as vectors for therapeutic gene delivery to breast tumours. European Cancer Organisation (ECCO).
R.M. Dwyer, F.P. Barry, T. O'Brien, M.J. Kerin. (2007) Investigation of the potential of human Mesenchymal Stem Cells (hMSC) as vectors for therapeutic gene delivery to breast tumours. European Cancer Organisation (ECCO). Barcelona, Spain Conference Poster [Details]
(2007) The role of Chemokine production by Primary Breast Cancer Stromal Cells in tumour progression.. Irish Association for Cancer Research.
Shirley M Potter-Beirne, Roisin M Dwyer, Micheal J Kerin (2007) The role of Chemokine production by Primary Breast Cancer Stromal Cells in tumour progression.. Irish Association for Cancer Research. Cork, Ireland Conference Poster [Details]
(2007) Bone Marrow-Derived Mesenchymal Stem Cells (MSCs) as potential interacting targets for circulating breast cancer cells. Irish Association for Cancer Research.
RM Dwyer, FP Barry, T O'Brien and MJ Kerin. (2007) Bone Marrow-Derived Mesenchymal Stem Cells (MSCs) as potential interacting targets for circulating breast cancer cells. Irish Association for Cancer Research. Cork, Ireland Conference Poster [Details]
(2007) Secretion and Expression of Monocyte Chemotactic Protein-1 (MCP-1) by Primary Breast Cancer Cell Populations.. Society of Academic & Research Surgery (SARS).
Shirley Potter Beirne, Roisin M Dwyer, Professor Micheal J Kerin (2007) Secretion and Expression of Monocyte Chemotactic Protein-1 (MCP-1) by Primary Breast Cancer Cell Populations.. Society of Academic & Research Surgery (SARS). Cambridge, UK Conference Poster [Details]
(2006) Mesenchymal stem cell–mediated stimulation of breast cancer cell migration. European Association for Cancer Research (EACR).
RM Dwyer, FP Barry, T O'Brien and MJ Kerin. (2006) Mesenchymal stem cell–mediated stimulation of breast cancer cell migration. European Association for Cancer Research (EACR). Budapest, Hungary Conference Poster [Details]

Editorial

  Year Publication
(2018) Evaluating a Novel Adipose Tissue Engineering Strategy for Breast Reconstruction Post-Mastectomy.
O' Halloran, N,Gilligan, K,Dolan, E,Khan, S,Dwyer, R,Kerin, M,Duffy, G,Lowery, A (2018) Evaluating a Novel Adipose Tissue Engineering Strategy for Breast Reconstruction Post-Mastectomy. Editorial [Details]
(2017) Autologous Adipose Derived Stem Cells: A Viable Option for Breast Reconstruction in Breast Cancer Patients.
Courtney, DG,Khan, S,Dwyer, RM,Malone, C,Sweeney, K,Barry, K,Lowery, A,Kerin, M (2017) Autologous Adipose Derived Stem Cells: A Viable Option for Breast Reconstruction in Breast Cancer Patients. Editorial [Details]

Meeting

  Year Publication
(2007) The role of primary stromal cell-derived chemokines in the breast tumour microenvironment.
Potter, SM,Dwyer, RM,Kerin, MJ (2007) The role of primary stromal cell-derived chemokines in the breast tumour microenvironment. Meeting [Details]
(2007) The role of primary stromal cell-derived chemokines in the breast tumour microenvironment.
Potter-Beirne, S,Dwyer, R,Kerin, MJ (2007) The role of primary stromal cell-derived chemokines in the breast tumour microenvironment. Meeting [Details]
(2008) Next generation mesenchymal stem cells for regenerative medicine applications: antibodies, peptides and lipoplexes for isolation, expansion and genetic modification of mscs.
Greiser, U,Hoare, M,Bowes, T,Dwyer, R,O'Toole, D,Mashayekhi, K,Murphy, M,O'Brien, T,Barry, F (2008) Next generation mesenchymal stem cells for regenerative medicine applications: antibodies, peptides and lipoplexes for isolation, expansion and genetic modification of mscs. Meeting [Details]
(2009) Sodium iodide symporter (NIS) mediated tracking of mesenchymal stem cell (MSC) migration to breast tumours in vivo.
Dwyer, R,Ryan, J,Havelin, R,Morris, J,O'Flatharta, C,Duffy, G,Miller, B,Liu, ZL,Barrett, H,Murphy, M,Barry, F,O'Brien, T,Kerin, M (2009) Sodium iodide symporter (NIS) mediated tracking of mesenchymal stem cell (MSC) migration to breast tumours in vivo. Meeting [Details]
(2010) BREAST TUMOUR STROMAL-EPITHELIAL INTERACTIONS STIMULATE INCREASED VEGF SECRETION AND ANGIOGENESIS IN VITRO AND IN VIVO.
Khan, S,Dwyer, RM,Potter, SM,Kerin, MJ (2010) BREAST TUMOUR STROMAL-EPITHELIAL INTERACTIONS STIMULATE INCREASED VEGF SECRETION AND ANGIOGENESIS IN VITRO AND IN VIVO. Meeting [Details]
(2010) DIGIT RATIO (2D:4D) AS A PREDICTOR OF BREAST CANCER PREDISPOSITION.
Devine, A,Kelly, J,Heneghan, H,Dwyer, R,Kerin, M (2010) DIGIT RATIO (2D:4D) AS A PREDICTOR OF BREAST CANCER PREDISPOSITION. Meeting [Details]
(2010) INVESTIGATION OF POTENTIAL ROLE OF CCL5 IN BREAST CANCER PROGRESSION.
Hartmann, MC,Dwyer, RM,Costello, M,Kerin, MJ (2010) INVESTIGATION OF POTENTIAL ROLE OF CCL5 IN BREAST CANCER PROGRESSION. Meeting [Details]
(2010) Potential of circulating chemokines as serum tumour markers in breast cancer.
Costello, M,Hartmann, M,Dwyer, R,Kerin, M (2010) Potential of circulating chemokines as serum tumour markers in breast cancer. Meeting [Details]
(2010) POTENTIAL ROLE FOR THYROID HORMONES IN REGULATION OF MAMMARY NIS EXPRESSION.
Ryan, J,Hennessy, E,Curran, CC,Morris, JC,Kerin, MJ,Dwyer, RM (2010) POTENTIAL ROLE FOR THYROID HORMONES IN REGULATION OF MAMMARY NIS EXPRESSION. Meeting [Details]
(2011) Cellular interactions in the primary tumour microenvironment.
Khan, S,Dwyer, RM,Sweeney, KJ,Kerin, MJ (2011) Cellular interactions in the primary tumour microenvironment. Meeting [Details]
(2011) TGF-beta 1 mediated stimulation of VEGF secretion by breast cancer cells.
Costello, M,Dwyer, RM,Ryan, J,Hartmann, M,Kerin, MJ (2011) TGF-beta 1 mediated stimulation of VEGF secretion by breast cancer cells. Meeting [Details]
(2012) Mesenchymal stem cells (MSCs) and colorectal cancer.
Hogan, NM,Dwyer, RM,Joyce, MR,Kerin, MJ (2012) Mesenchymal stem cells (MSCs) and colorectal cancer. Meeting [Details]
(2012) Plasminogen activator inhibitor-1 (PAI-1) secretion by mesenchymal stem cells and colorectal cancer cells in 3-dimensional culture.
Hogan, NM,Dwyer, RM,Joyce, MR,Kerin, MJ (2012) Plasminogen activator inhibitor-1 (PAI-1) secretion by mesenchymal stem cells and colorectal cancer cells in 3-dimensional culture. Meeting [Details]
(2012) Analysis of miR10b expression during disease progression in a murine model of breast cancer.
Waters, PS,Dwyer, RM,Kerin, MJ (2012) Analysis of miR10b expression during disease progression in a murine model of breast cancer. Meeting [Details]
(2012) Relationship Between Circulating and Tissue MiRNAs in a Murine Model of Breast Cancer.
Waters, PS,Dwyer, RM,Wall, D,McDermott, AM,Newell, J,Kerin, MJ (2012) Relationship Between Circulating and Tissue MiRNAs in a Murine Model of Breast Cancer. Meeting [Details]
(2012) Evaluation of MicroRNA Secretion From Cancer Cells in Vitro.
Glynn, CL,Dwyer, RM,Khan, SJ,Kerin, MJ (2012) Evaluation of MicroRNA Secretion From Cancer Cells in Vitro. Meeting [Details]
(2012) Active Secretion of MicroRNAs and Plasminogen Activator Inhibitor-1 (PAI-1) by Colorectal Cancer Cells and Associated Stroma In Vitro.
Hogan, NM,Dwyer, RM,Glynn, CL,Joyce, MR,Kerin, MJ (2012) Active Secretion of MicroRNAs and Plasminogen Activator Inhibitor-1 (PAI-1) by Colorectal Cancer Cells and Associated Stroma In Vitro. Meeting [Details]
(2012) Active Secretion of MicroRNAs by Breast Cancer Cells.
Glynn, CL,Dwyer, RM,Khan, S,Kerin, MJ (2012) Active Secretion of MicroRNAs by Breast Cancer Cells. Meeting [Details]
(2013) Analysis of mir-339-5p expression and function in breast cancer.
Khan, S,Brougham, C,Wall, D,Curran, C,Newel, J,Kerin, MJ,Dwyer, RM (2013) Analysis of mir-339-5p expression and function in breast cancer. Meeting [Details]
(2013) Relationship between circulating miRNAs and breast cancer epithelial subtype.
Duignan, MF,Brougham, C,Waters, PS,Dwyer, RM,Kerin, MJ (2013) Relationship between circulating miRNAs and breast cancer epithelial subtype. Meeting [Details]
(2013) Identification and validation of a microrna signature associated with breast cancer progression.
Waters, PS,Dwyer, RM,Hyland, P,Brougham, C,Wall, D,Kerin, MJ (2013) Identification and validation of a microrna signature associated with breast cancer progression. Meeting [Details]
(2013) Interactions between mesenchymal stem cells (MSCs) and colorectal cancer cells are mediated by plasminogen activator inhibitor type 1 (PAI-1).
Hogan, NM,Dwyer, RM,Joyce, MR,Kerin, MJ (2013) Interactions between mesenchymal stem cells (MSCs) and colorectal cancer cells are mediated by plasminogen activator inhibitor type 1 (PAI-1). Meeting [Details]
(2013) Relationship between MicroRNA-379 and Cyclin-B1 in breast cancer.
O'Neill, GJ,Khan, S,Sahrudin, A,Kerin, M,Dwyer, R (2013) Relationship between MicroRNA-379 and Cyclin-B1 in breast cancer. Meeting [Details]
(2013) Mesenchymal stem cell secreted PAI-1 impacts on colon cancer cell migration and proliferation.
Hogan, NM,Dwyer, RM,Joyce, MR,Kerin, MJ (2013) Mesenchymal stem cell secreted PAI-1 impacts on colon cancer cell migration and proliferation. Meeting [Details]
(2013) Impact of tumour epithelial subtype on circulating microRNAs in breast cancer.
Brougham, CL,Waters, PS,Wall, D,Kerin, MJ,Dwyer, RM (2013) Impact of tumour epithelial subtype on circulating microRNAs in breast cancer. Meeting [Details]
(2013) Relationship between Circulating Micrornas and Breast Cancer Intrinsic Subtype.
Brougham, CL,Waters, PS,Wall, D,Dwyer, RM,Kerin, MJ (2013) Relationship between Circulating Micrornas and Breast Cancer Intrinsic Subtype. Meeting [Details]
(2013) Mir-339-5p Acts as A Tumour Suppressor in Breast Cancer, Mediated at Least in Part Through Regulation of Cell Proliferation.
Khan, S,Brougham, CL,Wall, D,Newell, J,Kerin, MJ,Dwyer, RM (2013) Mir-339-5p Acts as A Tumour Suppressor in Breast Cancer, Mediated at Least in Part Through Regulation of Cell Proliferation. Meeting [Details]
(2013) Role of Mesenchymal Stem Cells in the colorectal cancer cell environment: stimulation of Epithelial-Mesenchymal Transition.
Hogan, NM,Joyce, MR,Dwyer, RM,Kerin, MJ (2013) Role of Mesenchymal Stem Cells in the colorectal cancer cell environment: stimulation of Epithelial-Mesenchymal Transition. Meeting [Details]
(2013) Circulating and Tissue Levels of miR-504 in colorectal and breast cancer.
Hogan, N,Khan, S,Huong, QTT,Brogham, C,Joyce, MR,Kerin, MJ,Dwyer, RM (2013) Circulating and Tissue Levels of miR-504 in colorectal and breast cancer. Meeting [Details]
(2013) Elevated expression of miR-106 and miR-202 in breast cancer.
McLoughlin, M,Glynn, CL,Waters, PS,Khan, S,Dwyer, RM,Kerin, MJ (2013) Elevated expression of miR-106 and miR-202 in breast cancer. Meeting [Details]

Reviews

  Year Publication
(2016) Exosome-encapsulated microRNAs as circulating biomarkers for breast cancer.
Joyce, DP;Kerin, MJ;Dwyer, RM (2016) Exosome-encapsulated microRNAs as circulating biomarkers for breast cancer. HOBOKEN: WILEY Reviews [DOI] [Details]
(2010) Advances in mesenchymal stem cell-mediated gene therapy for cancer.
Dwyer, RM;Khan, S;Barry, FP;O'Brien, T;Kerin, MJ (2010) Advances in mesenchymal stem cell-mediated gene therapy for cancer. LONDON: BIOMED CENTRAL LTD Reviews [DOI] [Details]

Workshops

  Year Publication
(2006) Breast Cancer Cells Migrate in Response to Bone Marrow-Derived Mesenchymal Stem Cells (MSCs). Sir Peter Freyer Surgical Symposium.
RM Dwyer, FP Barry, T O'Brien and MJ Kerin. (2006) Breast Cancer Cells Migrate in Response to Bone Marrow-Derived Mesenchymal Stem Cells (MSCs). Sir Peter Freyer Surgical Symposium. Galway, Ireland Workshops [Details]
(2007) Novel Chemokines Induce Migration of Breast Cancer Cells Towards Bone Marrow-Derived Mesenchymal Stem Cells. Society of Academic & Research Surgery (SARS).
RM Dwyer, FP Barry, T O'Brien and MJ Kerin. (2007) Novel Chemokines Induce Migration of Breast Cancer Cells Towards Bone Marrow-Derived Mesenchymal Stem Cells. Society of Academic & Research Surgery (SARS). Cambridge, UK Workshops [Details]
(2007) The Role Of Primarry Stromal Cell-Derived Chemokines In The Breast Tumour Microenvironment. Nottingham International Breast Cancer Conference.
Dwyer, R. (2007) The Role Of Primarry Stromal Cell-Derived Chemokines In The Breast Tumour Microenvironment. Nottingham International Breast Cancer Conference. Birmingham, UK Workshops [Details]
(2007) Distinct Chemokines Mediate Tumourigenicity Of Breast Cancer Cells. Sir Peter Freyer Surgical Symposium.
Shirley Potter, Roisin Dwyer, and Michael Kerin. (2007) Distinct Chemokines Mediate Tumourigenicity Of Breast Cancer Cells. Sir Peter Freyer Surgical Symposium. Galway, Ireland Workshops [Details]
(2008) Role of Monocyte Chemotactic Protein-1 (MCP-1) in the Primary Breast Tumour Microenvironment. Sir Peter Freyer Surgical Symposium.
Shirley M Potter, Roisin M Dwyer, Michael J Kerin (2008) Role of Monocyte Chemotactic Protein-1 (MCP-1) in the Primary Breast Tumour Microenvironment. Sir Peter Freyer Surgical Symposium. Galway, Ireland Workshops [Details]
(2008) Elevated Plasma SDF-1 alpha Correlates with Tumour Grade. Society of Academic & Research Surgery (SARS).
Shirley Potter Beirne, Roisin Dwyer, Kate Harrington and Michael Kerin. (2008) Elevated Plasma SDF-1 alpha Correlates with Tumour Grade. Society of Academic & Research Surgery (SARS). Birmingham, UK Workshops [Details]

Honours and Awards

  Year Title Awarding Body
2013 BREAST-PREDICT Collaborative Cancer Research Centre Irish Cancer society
2012 Millenium Fund NUI Galway
2012 Irish Cancer Society Researcher of the Year Award Irish Cancer Society
2008 Research Project Grant Irish Cancer Society
2007 Research Project Grant Health Research Board
2005 National University of Ireland Postdoctroal Fellowship in the Sciences NUI

Professional Associations

  Association Function From / To
European Association for Cancer Research (EACR) Member 01-MAY-08 /
European Society for Gene and Cell Therapy (ESGCT) Member 01-AUG-09 /
American Association for Cancer Research (AACR) Member 01-NOV-08 /
Matrix Biology Ireland Council Member 01-FEB-16 /
American Society of Gene and Cell Therapy (ASGCT) Member 01-AUG-03 /

Committees

  Committee Function From / To
ACREC Member 02-APR-18 /
Board of School of Medicine Member 02-JUN-17 /
School of Medicine Research Committee Current Member, previous Chairperson 01-FEB-17 /
College of Medicine Nursing and Health Sciences (CMNHS) Research Committee Committee Member 13-APR-16 /
College of Medicine Nursing and Health Sciences (CMNHS) Graduate Studies Committee Committee Member 10-MAR-16 /
School of Medicine Executive Committee Research Representative 23-FEB-16 /
School of Medicine Undergraduate Research Committee Chairperson 01-SEP-14 /

Employment

  Employer Position From / To
NUI Galway Lecturer in Translational Science 03-SEP-12 /
NUI Galway Research Fellow 01-NOV-05 / 31-AUG-12
Mayo Clinic Postdoctoral Scientist 01-APR-02 / 31-MAR-05

Education

  Year Institution Qualification Subject
1997 University College Dublin BSc (Hons) Science
2002 University College Dublin PhD Medicine
2015 NUI Galway MASTERS DEGREE (LEVEL 9) Academic Practice
1998 Dublin City University MASTERS OF SCIENCE Biological Sciences

Community Engagement

  Title Type From / To
Outreach Mini-Med School /
Outreach Youth Academy /
Outreach Pint of Science /

Recent Postgraduate Students

  Graduation Name Degree Primary Supervisor
2017 Killian O'Brien PhD Y
2017 Doireann Joyce PhD Y
2012 Shirley Potter PhD Y
2010 John Kelly Y
2014 Claire Glynn PhD Y
2014 Sonja Khan PhD Y
2014 Peadar Waters Y
2009 Alan Molloy MASTERS DEGREE (LEVEL 9) Y
2014 Marion Hartmann PhD Y
2014 James Ryan PhD Y
2014 Niamh Hogan Y
2016 Cillian Clancy Y
2011 Fiachra Martin Y

Current Postgraduate Students (Research)

  Student Degree Type Type
Yashna Chabria Doctorate - Structured Ph.D (Medicine) Supervisor
Yi-Jan Lim Doctorate - Structured Ph.D (Medicine) Co-supervisor (1)
Elan Mc Carthy Doctorate - Structured Ph.D (Medicine) Supervisor
Ritihaas Challapalli Doctorate - Structured Ph.D (Medicine) Co-supervisor (1)
Clodagh O'Neill Doctorate - Structured Ph.D (Medicine) Supervisor

Modules Taught

  Term/Year Module Title Module Code Subject / Desc
2013/14 - 2017/18 Surgical Lab Skills I MD560
2020/21 - Harnessing the Basic Biology of Cancer for Development of Novel Therapeutics MD1541
2018/19 to date Translational Research MD1550
2018/19; 2019/20 Imaging in Translational Cancer Research AN1504
2016 to date Translational Science SSM GAL021

Internal Collaborators

  Name Description of Collaboration
Professor Timothy O'Brien
Professor Peter Dockery
Dr Aideen Ryan
Professor Michael Kerin
Dr Linda Howard
Dr Mark Foley
Professor Martin Leahy

External Collaborators

  Name Organisation / Institute Country Description of Collaboration
Professor Harrison Barrett University of Arizona U.S.A.
Professor Zhonglin Liu University of Arizona U.S.A.
Professor John Morris Mayo Clinic, Rochester, Minnesota U.S.A.