Technical Capabilities

· Clinical and preclinical neuroimaging: MRI and PET

· Clinical & experimental EEG/ERPs/EMG neurophysiology

· Quantitative sensory testing in healthy human participants and patients

· Neuropsychological and clinical assessment of cognition

· Eye-tracking and pupillometry

· Clinical and preclinical genomics: genotyping and next-generation sequencing

· Generation of human pluripotent stem cells (iPSc)

· Preclinical disease models: anxiety, autism, depression, multiple sclerosis, Parkinson’s disease, pain, spinal cord injury, stress, stroke

· Preclinical behavioural neuroscience

· In vitro and Ex vivo disease models: Huntington’s disease, neurodegeneration, neuroinflammation, Parkinson’s disease, stroke

· In vivo microdialysis

· Proteomics/lipidomics: mass spectrometry

· Microscopy (incl. electron and confocal), histology, autoradiography and neurostereology

· Cell/Enzyme based assays

· Molecular biology (e.g. Western blot, RT-qPCR)

· Electrophysiology

· Assays for trinucleotide repeat expansions

· Devlopment and validation of rapid assays for biomarkers found in a range of body fluids

· Histological and immunocytochemical characterisation

· Constraint-based modelling of metabolism