Module: Health and Disease I

Module Code: MD 201

Academic Weighting: 15 credits

Teaching Period: Year 2, Semester 2 (12 weeks).

Contributing Disciplines:Pathology, Bacteriology and Public Health & Health Promotion (PHHP) and Pharmacology

Departmental Contributions: Total: 138 teaching hours (46% lectures, and 54% non-didactic sessions)

Lectures: Pathology 47%; Bacteriology 20%; Public Health and Health Promotion 22%; Pharmacology 11%

Non-didactic sessions: Pathology 54%; Bacteriology 31%; PHHP 15% 

Module Director: Dr. Teck Wee Boo, Consultant Microbiologist/Senior Lecturer.

Module Description

The module aims to introduce to students the various disciplines, key concepts and knowledge that underpin the development, diagnosis and management of clinical conditions. The module will highlight the interplay between molecular, cellular, microbiological, pharmacological, environmental, epidemiological and social mechanisms in disease development and progression. Principles of health promotion and disease prevention at individual and population levels will also be introduced.

Learning outcomes

Discuss the interplay of molecular, cellular, microbiological, pharmacological and environmental factors in the causation of different diseases, and the clinical relevance of  such underlying mechanisms. 

Describe the mechanisms, aetiologies and responses relating to cell injury, death, growth and neoplasia, as well as the subsequent healing, repair and/or neoplastic processes. 

Explain the basic alterations of haemodynamic processes including thrombosis, ischaemia, infarction and shock. 

Explain the principles and application of biomedical statistical methods in population health and clinical settings. 

Discuss the functions of public health and health promotion, including epidemiology, healthcare needs assessment, disease prevention relating to both individual and population health services, and wider determinants of health. 

Discuss pathobiology, aetiology, diagnosis, as well as general principles in surveillance, prevention, control and management of infectious diseases.

Explain the principles and application of infection prevention/control measures and rational use of antimicrobial agents in healthcare settings. 

Describe the pathobiology, microbiology, pharmacology, surveillance and prevention of cardiovascular disorders including atherosclerosis, myocardial infarction, valvular disorders, cardiomyopathy, cardiac failure and hypertension. 

Describe the pathobiology, microbiology, surveillance and prevention of respiratory disorders including asthma and other allergic disorders, pneumonia, tuberculosis, inflammatory disorders, COPD, cystic fibrosis and neoplasia.                                   


Educational Materials


  • Robbins Basic Pathology. Kumar V., Cotran R.S, Robbins S. 7th Edition.
  • General and Systemic Pathology. Underwood J.C.E. 4th Edition.
  • Pathologic basis of disease. Robbins & Cotran. 8th Edition.
  • Wheaters Basic Pathology. Burkitt H.G., Stevens A., Lowe J.S., Young B. 3rd Edition.
  • Department of Bacteriology Handbook
  • Rang, H.P., Dale, Ritter, Flower & Henderson (2011): Pharmacology, 7th Edition. Churchill Livingstone. ISBN 978-0-7020-3471-8.
  • Golan, D.E., et al., (2011) Principles of Pharmacology 3rd edition. LWW. ISBN 9781451118056
  • Harvey, R.A., (2011) Lippincott’s Illustrated Reviews Pharmacology, 5th Edition. LWW. ISBN 9781451143201
  • Health and Disease Handbook


IT (software + version)


Website is already on the college server - CENTRAL CD’s


http:// (The virtual autopsy site)


Module Assessment:

1st sitting:  Continuous Assessment Presentations (15%) - 10% is Pathology and 5% is Bacteriology

                   End of module 2 x 2 hour computer based MCQs (85%)


2nd sitting: Continuous Assessment Presentations (15%) - 10% is Pathology and 5% is Bacteriology

                     Autumn   2 x 2 hour computer based MCQs (85%)

Attendance is monitored during all types of teaching. Students with < 70% attendance may not be permitted to take the exam.